A navigation guide wire (1 ) through an anatomical apparatus, for example a vascular
system, unusually capable of being safely positioned
proximate to bifurcations, comprises: - an elongated body (19) having a proximal end (21 ), a distal end (20), and a longitudinal extension along an axis (x-x) extending at least from said proximal end to said distal end; - at least one first proximal portion (4) having a predetermined first
flexural rigidity (KfI ) capable of a first predetermined flexure in at least one plane comprising at least one portion of said longitudinal axis in order to allow a first curvature to said proximal portion when bending stressed, while ensuring a predetermined elastic return in a rectilinear position of the elongated body proximal portion when not subjected to stresses; - at least one second
distal portion (3) having a predetermined second
flexural rigidity (Kf2), the amount of which is equal to or higher than said first
flexural rigidity of said at least one first proximal portion, capable of a predetermined flexibility of said second
distal portion in order to obtain a second curvature when bending stressed in at least one plane comprising at least one portion of said longitudinal axis, while ensuring an elastic return to a rectilinear position of said
distal portion of said elongated body when not subjected to stress; - at least one intermediate length (6), arranged between said first proximal portion and said second distal portion, having a third flexural rigidity (Kf3) essentially lower than said first flexural rigidity (KfI ) and said second flexural rigidity (Kf2), which allows a predetermined flexibility capable of a third curvature substantially more pronounced compared to said first curvature and second curvature, so as to allow a considerable direction change between said first proximal portion (4) and said second distal portion (3).