The invention discloses a cefamandole nafate compound for injection. The cefamandole nafate compound is a crystal compound; and in X-ray powder diffraction, main peaks are shown at diffraction angles of 5.9+ / -0.01 degrees, 6.02+ / -0.01 degrees, 11.3+ / -0.01 degrees, 16.9+ / -0.01 degrees, 17.9+ / -0.01 degrees, 18.0+ / -0.01 degrees, 21.1+ / -0.01 degrees, 22.0+ / -0.01 degrees, 22.1+ / -0.01 degrees, and 23.5+ / -0.01 degrees. The invention also discloses a medicine composite containing the cefamandole nafate compound. The cefamandole nafate crystal is good in stability and high in fluidity; when a cefamandole nafate sterile powder injection is prepared, the sub-package amount of active medicine components is accurate and the operation is facilitated; and besides, the sterile powder injection is not easily adhered to bottles, and is very convenient regardless of being used independently or mixed with other medicine powder. The cefamandole nafate compound does not degrade fundamentally and can be placed for a long time, thereby having a great advantage in medicine preparation.