The invention discloses a radix paeoniae alba formula particle and preparation and quality control methods thereof. The formula particle is made from radix paeoniae alba decoction pieces used as raw materials, and the decoction pieces are processed by the technological processes of two times of water extraction, depressurization, concentration, spraying, drying, and the like to gain the radix paeoniae alba formula particle; and one gram of radix paeoniae alba formula particle is equivalent to 10 to 20 gram of crude medicines, and the quality of the radix paeoniae alba decoction pieces and that of the radix paeoniae alba formula particle are respectively discriminated by the infrared fingerprint spectra. The radix paeoniae alba formula particle of the invention has the advantages of integrated and advanced production process, high special and controllable quality control standard and advanced and realizable process, and a test method for the quality standard is scientific, advanced, fast and highly practical. as Proven by experiments, the ingredient of a herbal decoction prepared by the radix paeoniae alba formula particle of the invention is equivalent to the ingredient of a radix paeoniae alba contained classic formula co-decoction, the full ingredient formula particle process is achieved, and the process of the invention is proven to be reasonable; and the invention applies the infrared spectra technology to the quality control of the traditional Chinese medicine, thereby fast solving the principle problem of traditional Chinese medicine discrimination in the macroscopical quality control of the traditional Chinese medicine.