The application discloses a Raman spectrum
fluorescence baseline
correction method and device, the method comprises the following steps: collecting a
time domain signal of a sample to be measured, and obtaining an IRF function of a
sample collection system of the sample to be measured; pre-
processing the
time domain signal, and performing
deconvolution on the pre-processed
time domain signal and the IRF function to obtain a
deconvolution result; fitting the latter half data of the
deconvolution result by using a
support vector regression model to obtain a fitting curve; wherein, a
radial basis function is used as a kernel function, and the hyperparameters of the
support vector regression model are optimized by using a grid search and cross-validation method; performing difference operation on the deconvolution result and the fitting curve to obtain a Raman
decay curve; and performing windowing and averaging on the Raman
decay curve to obtain a Raman spectrum. The application does not need to preset a
fluorescence decay model and parameters thereof, utilizes the characteristics of the time domain signal data itself, processes the IRF deconvolution result by using the
support vector regression model, predicts a time domain baseline, can greatly improve the signal-to-
noise ratio of extracted Raman signals, achieves good effects, and is suitable for practical application.