44 results about "Pregnancy induced" patented technology

A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and the method for preparing the therapeutic agents is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive / pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or other method. Further, a method of using of a biomarker, the presence of chymotrypsin in the maternal GI tract to determine the likelihood of developing preeclampsia, pregnancy induced hypertension, and eclampsia / toxemia is disclosed.

The invention provides methods of treating and preventing asthma, laryngitis, symptomatic gastroesophageal reflux disease, pregnancy-induced gastroesophageal reflux disease, noncardiac chest pains, coughing, apnea, dyspepsia, inflammatory bowel disease, irritable bowel syndrome, gastritis, stress ulcers, bleeding peptic ulcers, acute gastrointestinal bleeding, infectious enteritis, collagenous colitis, lymphocytic colitis, chronic diarrhea in immunocompromised patients, esophageal ulcers in immunocompromised patients, idiopathic gastric acid hypersecretion, gastroparesis, gastrointestinal motility disorders, Zollinger-Ellison syndrome, short bowel syndrome, emesis, regurgitation, early satiety, chronic sore throat, abdominal pain, abdominal bloating, nausea, sour stomach, diarrhea, constipation, bacterial infections, refractory ulcers, gastrointestinal disorders induced by NSAIDs, Barrett's esophagus, gastrointestinal disorders caused by steroids, gastrointestinal disorders induced by cholinergic compounds, and fungal or viral-induced ulcers in the gastrointestinal tract by administering a therapeutically effective amount of at least one proton pump to a patient in need thereof. The invention also provides on demand relief of symptoms associated with gastroesophageal reflux disease (GERD), and provides relief from symptoms caused by the consumption of excessive amounts of food and / or alcohol by administering a therapeutically effective amount of at least one proton pump inhibitor to a patient in need thereof. The invention also provides methods for treating parasitic infections, such as malaria, by administering a therapeutically effective amount of at least one proton pump inhibitor to a patient in need thereof.

A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and the method for preparing the therapeutic agents is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive / pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or other method. Further, a method of using of a biomarker, the presence of chymotrypsin in the maternal GI tract to determine the likelihood of developing preeclampsia, pregnancy induced hypertension, and eclampsia / toxemia is disclosed.

The present invention relates to the prognosis and risk assessment in pregnant women to develop pregnancy-induced hypertension and / or preeclampsia by the determination of marker levels.

A composition is provided to prevent, limit the effects of, delay the onset of, or treat one or more of the causes, symptoms or complications of gestational hypertension, preeclampsia, eclampsia and / or intrauterine growth restriction. The composition comprises a therapeutically effective amount of an antibody that reacts immunologically with or binds digoxin and has a high dose of digoxin binding capacity as the active ingredient. There is also provided a method of preventing, limiting the effects of, delaying the onset of, or treating a cause, symptom or complication of gestational hypertension, preeclampsia, eclampsia or intrauterine growth restriction, comprising the step of administering to a mammal a composition comprising a therapeutically effective amount of an antibody that reacts immunologically with or binds digoxin and has a high dose of digoxin binding capacity.

A method and kit for determining whether an animal is not pregnant, or is pregnant following a breeding. The level of expression of a pregnancy induced protein is determined in an animal for which pregnancy status information is desired and the level is compared to that of the level in animals that are not pregnant.

The present invention relates to the prognosis and risk assessment in pregnant women to develop pregnancy-induced hypertension and / or preeclampsia by the determination of marker levels.

Provided are: a method for predicting the onset of pregnancy-induced hypertension (PIH) by precisely detecting abnormalities that occur before the onset of PIH (where such abnormalities have been impossible to detect by various conventional testing methods for PIH) while imposing less of a burden on a subject; a method for evaluating a fetus and placental functions in PIH; and a method for detecting PIH, which comprises measuring the level of human lipocalin-type prostaglandin D synthase (L-PGDS) in a body fluid sample collected from a subject.

The invention relates to selenium-rich edible oil suitable for women and children. The selenium-rich edible oil is characterized by comprising the following components: 10% of olive oil, 35%-45% of Enshi selenium-rich camellia oil, 15%-25% of Enshi selenium-rich walnut oil, 20% of peanut oil, and 10% of Enshi selenium-rich perilla oil. All the raw materials are stirred and mixed evenly to prepare the selenium-rich edible oil. According to the invention, linolenic acid can be protected from being oxidized and thus the shelf life of the selenium-rich edible oil is prolonged; the selenium-rich edible oil has excellent prevention and elimination effects on pregnancy-induced hypertension and accompanying heart disease as well as skin spots of women, and is crucial for the development of intelligence, vision, brain and heart of a fetus and significant for preventing free radicals from causing peroxidation damage to a fetus and a mother.

A traditional Chinese medicine for curing pregnancy-induced hypertension syndrome belongs to a traditional Chinese medicine for curing pregnancy diseases. The components contain: 15g of viscum album, 15g of spina date seed, 20g of eucommia bark, 20g of salvia miltiorrhiza, 10g of rhizoma gastrodiae, 10g of largehead atractylodes rhizome, 10g of rhizoma atractylodis, 10g of dried orange peel, 12g of shell of areca nut, 12g of tuckahoe, 6g of cassia twig, 6g of amomum villosum and 6g of liquorice. The substances in the prescription are made from natural traditional Chinese medicine plus traditional preparing methods. The materials are easy to collect, the prescription and the preparation methods are simple, and the cost of medicine preparation is low. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from pregnancy-induced hypertension syndrome, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

Provided are: a method for predicting the onset of pregnancy-induced hypertension (PIH) by precisely detecting abnormalities that occur before the onset of PIH (where such abnormalities have been impossible to detect by various conventional testing methods for PIH) while imposing less of a burden on a subject; a method for evaluating a fetus and placental functions in PIH; and a method for detecting PIH, which comprises measuring the level of human lipocalin-type prostaglandin D synthase (L-PGDS) in a body fluid sample collected from a subject.

The invention discloses a Chinese medicinal composition for treating pregnancy-induced hypertension syndrome. The Chinese medicinal composition consists of the following Chinese herbal medicines in part by weight: 24 parts of astragalus, 18 parts of largehead atractylodes rhizome, 15 parts of tuckahoe, 15 parts of poria peel, 10 parts of plantain seed, 10 parts of rhizoma alismatis, 15 parts of Chinese wax gourd peel, 12 parts of gastrodia elata, 15 parts of corn stigma, 15 parts of medlar, 12 parts of Himalayan teasel root, 12 parts of fried eucommia ulmoides oliv, 12 parts of fish glue, 10 parts of tangerine peel and 15 parts of raw hawthorn. The invention has the advantages that: the Chinese medicinal composition is convenient to take, wide in medicinal source and low in price, does not have toxic or side effects, does not affect fetal growth, and has an obvious curative effect; and the effective rate and the cure rate of the Chinese medicinal composition for treating the pregnancy-induced hypertension syndrome are 97 percent and 95 percent respectively.

The invention discloses a new liver and kidney nourishing decoction preparation (a novel medicament delivery system) for treating hepatitis and a preparation method thereof, which belong to the field of biomedicine. The new preparation comprises six medicinal materials, namely coastal glehnia root, dwarf lilyturf tuber, Chinese angelica, rehmannia root, barbary wolfberry fruit and szechwan Chinaberry fruit, and a proper amount of extract of a coptis component serving as main raw materials, and is prepared by the following steps of: extracting and separating; properly adding medicinal auxiliary materials; and finally preparing by the conventional process of formulations such as sprays, ointments (or syrups), pills, aerosols, dispersible tablets, orally disintegrating tablets, targeting preparations, controlled release preparations and the like. Through improved technology, the curative effect of the conventional compound prescription is further improved, so the technical requirement of controllable quality of the modern Chinese traditional medicine is met, the side effect is also reduced, and the compliance of a clinical medicament is improved. The new preparation has the unique effects of treating difficult and complicated diseases such as the hepatitis, hepatocirrhosis, liver cancer, gastritis, pregnancy-induced hypertension syndrome, tubal ligation syndrome, herpes zoster, central retinitis, recurrent aphtha, other gynecological diseases and the like, so that the new preparation has unique clinical application value.

The invention discloses a drug for treating pregnancy-induced hypertension. The drug comprises the following active ingredients by weight: 20g of ganoderma lucidum, 20g of stir-baked cortex eucommia, 20g of herba taxilli, 15g of dipsacus asperoids, 15g of citrus chirocarpus, 15g of rhizoma dioscoreae, 10g of silybum marianum, 10g of radix puerariae, 10g of dogbane leaf, 10g of lotus leaf, 10g of concha haliotidis, 10g of hawthorn, 10g of stigma maydis, 5g of christina loosestrife herb, 5g of Chinese pyrola herb, 5g of radix scutellariae, 5g of radix codonopsis and 5g of radix glycyrrhizae. The traditional Chinese medicine is used for treating pregnancy-induced hypertension, so that the total efficiency can achieve 100%, and the normal growth of fetuses is not influenced.

The invention discloses a traditional Chinese medicine for treating pregnancy-induced syndromes. The traditional Chinese medicine comprises the following raw materials by weight: 30-50g of concha haliotidis, 20-30g of wolfberry, 10-20g of radix paeoniae alba, 10-20g of uncaria rhynchophylla, 10-20g of radix curcumae, 10-20g of tabasheer, 10-20g of raw dens draconis, 10-20g of poria cocos, 10-20g of pericarpium arecae, 8-15g of sunflower, 8-12g of root of three-nerved spicebush, 8-12g of pawpaws, 8-12g of herba aristolochiae, 8-12g of yam, 8-12g of akebiaquinata and 8-12g of bulb of fritillary. The raw materials are combined and have the effects of tonifying spleen and kidney, soothing liver and harmonizing stomach, strengthening foundation, nourishing blood and preventing abortion, reducing liver and gall fire, nourishing liver and gall yin blood, harmonizing liver and stomach and healing various symptoms. The traditional Chinese medicine not only can be used for treating the syndromes such as vomitus gravidarum, depression, hypertension and rage, but also can be used for preventing miscarriage and tonifying nausea, and is worthy of clinic popularization and application.

A warm palace abdominal belt, comprising a belt body with connectors at the end, and an air-permeable inner layer cloth sewn with the belt body close to the lower abdomen of a woman, the belt body and the inner layer cloth An accommodation space with a pocket is formed between them, and a moxibustion device is arranged in the accommodation space, and the moxibustion device includes a casing and a pad cloth arranged at the bottom of the casing. There is an insulating layer and a flame-proof layer, and a drawable moxa burning platform and a heating wire located above the moxa burning platform are arranged inside the casing, and the heating wire is electrically connected to a controller placed outside the belt body. The invention combines traditional Chinese medicine moxibustion with modern technology, and has reasonable structure, simple operation and convenient use. It has the advantages of warming the meridian and dispelling cold, protecting the nest and warming the palace, removing blood stasis and relieving pain, improving circulation, promoting metabolism, facilitating normal postpartum uterine contraction, and repairing muscle damage caused by pregnancy and childbirth. It can treat women's "uterine cold" without side effects. The effect is remarkable.

The invention provides a method for preparing corn stigma tea. The method comprises the following steps of: 1, selection of raw materials, namely taking 100g of fresh corn stigmas or 30g of dry corn stigmas; and 2, preparation, namely cleaning the corn stigmas and then soaking for half an hour by using clean water, then dumping into an earthenware pot together with soaking water, boiling and decocting for 20 minutes with mild fire, and removing the corn stigmas to obtain the corn stigma tea. The corn stigma tea prepared by the method has the effects of treating pregnancy-induced hypertension and edema.

A method and kit for determining whether an animal is not pregnant, or is pregnant following a breeding. The level of expression of a pregnancy induced protein is determined in an animal for which pregnancy status information is desired and the level is compared to that of the level in animals that are not pregnant.

A lentiviral vector was used to produce non-human animals that express human sFLT1 specifically in the murine placenta, to provide model animals of diseases such as pregnancy-induced hypertension syndrome that are close to the clinical conditions, methods for producing the model animals, methods of screening for candidate compounds as therapeutic agents for diseases such as pregnancy-induced hypertension syndrome by using the model animals, and therapeutic agents for diseases such as pregnancy-induced hypertension syndrome. As a result, the model animals were found to exhibit symptoms that are very close to the clinical conditions in human, which are presentation of hypertension as well as placental insufficiency, intrauterine growth retardation, glomerulosclerosis, and proteinuria during pregnancy, and improvement of those symptoms postpartum. Furthermore, when pravastatin was administered to this model animal, it was found that diseases such as pregnancy-induced hypertension syndrome were improved by the activation of placenta-derived growth factor (PIGF) which antagonizes sFLT1.

The invention discloses a traditional Chinese medicine preparation for treating dry stool during pregnancy. 30 servings of yam, white peony root, walnut kernel, black sesame, 8 servings of amomum, and 20 servings of honey; the selected medicinal materials have the effects of nourishing blood and nourishing yin, moistening intestines and laxative, promoting body fluid and quenching thirst, nourishing qi and invigorating spleen . The immune function of the body is improved through oral administration, and it has a good curative effect on the dry stool of pregnancy caused by various etiologies, and is convenient to take. It is found through clinical application that the present invention has the advantages of rapid action, obvious therapeutic effect, good tolerance, low cost and no toxic or side effects.

The invention discloses a pharmaceutical composition for treating pregnancy-induced hypertension (PIH) in order to solve the problem of the treatment of PIH. The pharmaceutical composition for treating PIH is characterized in that: the pharmaceutical composition is processed by various traditional Chinese medicines, and comprises the following components by weight ratio: 6 to 10 parts of herb of rose glorybind, 8 to 15 parts of chrysanthemum, 8 to 15 parts of lotus plumule, 6 to 10 parts of tabasheer, 6 to 10 parts of ebony, 8 to 15 parts of semen celosiae, 6 to 10 parts of towel gourd vegetable sponge, 8 to 15 parts of papaya and 3 to 6 parts of madder root. Clinical trials prove that the pharmaceutical composition for treating PIH has the characteristics of good efficacy and higher safety, and is worthy of clinical application and popularization.

The invention belongs to the field of health-care food, and discloses black sesame rice noodles. The black sesame rice noodles consist of the following raw materials in parts by weight: 5-7 parts of abone-promoting mineral composition, 0.002-0.004 part of vitamin D, 0.3-0.5 part of momordica grosvenori swingle extract particles, 4-6 parts of soybeans, 4-6 parts of black soya beans, 20-30 parts ofblack sesame and the balance of rice, and the total parts by weight of the raw materials are 100. The rice noodles are rich in nutrient substances such as calcium and zinc, not only can provide abundant and full nutrient substances for pregnant women and increase the success rate of pregnancy of the pregnant women, but also can prevent pregnancy-induced hypertension of the pregnant women and promote development of bones of a fetus.

The invention discloses a traditional Chinese medicine preparation for treating pregnancy-induced hypertension syndrome and a preparation method of the traditional Chinese medicine preparation and belongs to the field of traditional Chinese medicines. The active ingredients of the traditional Chinese medicine preparation are prepared from the following raw materials: henbit, catharanthus roseus, chufa, luisia morsei, lumbricus, eucommia ulmoides, lily of the valley, lespedesa virgata, Chinese lobelia, chinaroot greenbrier, mesona blume, Siberian cockleburs, orchis, oyster-green, wall spider egg-case and munronia henryi harms. The medicinal materials selected for the traditional Chinese medicine preparation are reasonably combined and meet the research theory of traditional Chinese medicines and modern medicines, so that the preparation has the functions of inducing diuresis to alleviate edema, promoting blood circulation to remove meridian obstruction, soothing the nerves and relieving pain and reducing blood pressure and enriching blood and is convenient to use, good in absorption effect and free of adverse reactions and toxic and side effects. Clinical verifications show that the preparation can be used for tonifying spleen and inducing dieresis, strengthening heart and tonifying spleen, invigorating lung and regulating qi and improving internal and external environments of a human body so as to treat or alleviate various symptoms of pregnancy-induced hypertension syndrome and is suitable for clinical treatment and nursing popularization and application for pregnancy-induced hypertension syndrome.

The invention relates to the technical field of traditional Chinese medicines and in particular to a traditional Chinese medicine for treating female sterility infertility. The traditional Chinese medicine is used for intravaginal administration, and is prepared from the following raw materials in parts by weight: 10-55.5 parts of radix angelicae sinensis, 13.4-50 parts of radix rehmanniae, 8.5-45.6 parts of radix sophorae flavescentis, 11-52 parts of semen cuscutae, 12.5-50 parts of radix astragali, 15.4-45.5 parts of radix cyathulae, 10-48. 5 parts of fructus foeniculi, 15-50 parts of commoncnidium fruit, and 10-50.5 parts of fructus jujubae. The traditional Chinese medicine is used for, through the coordinate application of the radix angelicae sinensis, the radix rehmanniae, the radixsophorae flavescentis, the semen cuscutae, the radix astragali, the radix cyathulae, the fructus foeniculi, the common cnidium fruit, and the fructus jujubae, conditioning uterine cold, arrested fetaldevelopment, pregnancy-induced hypertension syndrome, habitual abortion, puerperal disorder, irregular menstruation and gynecological diseases, so the traditional Chinese medicine can be used for treating the female sterility infertility.

The invention discloses a Chinese herbal medicine formula for treating pregnancy-induced hypertension and a preparation method of the Chinese herbal medicine. The Chinese herbal medicine is prepared from the following Chinese herbal medicine raw materials by weight: 30g of gastrodia elata, 30g of uncaria, 30g of concha margaritiferallsta, 20g of concha haliotidis, 15g of oyster, 15g of achyranthes roots, 20g of artemisia apiacea, 15g of pericarpium citri reticulatae, 20g of herba aristolochiae, 20g of rhizoma alismatis, 25g of chrysanthemum, 15g of silkworm larva, 25g of arabic cowry shells, 30g of polygala tenuifolia, 15g of poria cocos, 20g of fresh aloe peel, 20g of pericarpium arecae and 20g of rhizoma pinellinae praeparata. The Chinese herbal medicine has the advantages of remarkable effect, no influence on health of a fetus and no side effects.

A lentiviral vector was used to produce non-human animals that express human sFLT1 specifically in the murine placenta, to provide model animals of diseases such as pregnancy-induced hypertension syndrome that are close to the clinical conditions, methods for producing the model animals, methods of screening for candidate compounds as therapeutic agents for diseases such as pregnancy-induced hypertension syndrome by using the model animals, and therapeutic agents for diseases such as pregnancy-induced hypertension syndrome. As a result, the model animals were found to exhibit symptoms that are very close to the clinical conditions in human, which are presentation of hypertension as well as placental insufficiency, intrauterine growth retardation, glomerulosclerosis, and proteinuria during pregnancy, and improvement of those symptoms postpartum. Furthermore, when pravastatin was administered to this model animal, it was found that diseases such as pregnancy-induced hypertension syndrome were improved by the activation of placenta-derived growth factor (PIGF) which antagonizes sFLT1.