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326 results about "Volunteer activity" patented technology

Volunteering is generally considered an altruistic activity where an individual or group provides services for no financial or social gain "to benefit another person, group or organization". Volunteering is also renowned for skill development and is often intended to promote goodness or to improve human quality of life.

Methods and reagents to detect and characterize norwalk and related viruses

Double-stranded cDNA was synthesized from nucleic acid extracted from Norwalk virus purified from stool specimens of volunteers. One clone was isolated from a cDNA library constructed in a pUC-13 vector after amplification of the cDNA. The specificity of this cDNA (pUCNV-953) was shown by hybridization assays. The cDNA reacted with post (but not pre-) infection stool samples from Norwalk volunteers and with highly purified Norwalk virus, but not with other common enteric viruses such as hepatitis A virus and rotavirus. Finally, the probe detected virus in the same fractions of CsCl gradients in which viral antigen was detected using a specific Norwalk virus radioimmunoassay, and particles were detected by immune electron microscopy. Single-stranded RNA probes derived from the DNA clone after subcloning into an in vitro transcription vector were also used to show that the Norwalk virus contains a ssRNA genome of about 8 kb in size. The original clone was also used to detect additional cDNAs which represent at least 7 kb of nucleic acid of the Norwalk genome. The availability of a Norwalk-specific cDNA and the first partial genome sequence information allow rapid cloning of the entire genome and of establishment of sensitive diagnostic assays. Such assays can be based on detection of Norwalk virus nucleic acid or Norwalk viral antigen using polyclonal or monoclonal antibodies to proteins expressed from the cDNA or to synthetic peptides made based on the knowledge of the genome sequence. Assays using proteins deduced from the Norwlk virus genome and produced in expression systmes can measure antibody responses. Vaccines made by recombinant DNA technology are now feasible.
Owner:BAYLOR COLLEGE OF MEDICINE

Microcrystalline zeaxanthin with high bioavailability in oily carrier formulations

Zeaxanthin (ZX) or other medically or commercially important carotenoids can be prepared in microcrystalline form, in an oily carrier liquid, to increase their bioavailability following oral ingestion. Initial processing is carried out to prepare a “rough” or “coarse-grained” carotenoid preparation containing relatively large particles of the ZX or other carotenoid, in a suitable form such as a lyophilized stable powder. The coarse-grain preparation is dissolved in a suitable solvent such as tetrahydrofuran, and mixed with a carrier liquid comprising a digestible oil (such as a vegetable oil) and an emulsifying agent. The resulting oil-and-solvent mixture is injected, along with inert gas such as nitrogen, into a vacuum chamber, where a suitable vacuum and temperature combination is used to remove the solvent in a rapid “flash” manner which does not give the carotenoid crystals time to grow larger through accretion or aggregation. This generates a microcrystalline suspension containing very small particles of the ZX or other cartenoid, in the oily liquid carrier. This product can be further processed if desired, or it can be loaded directly into watertight capsules for oral ingestion. Tests on human volunteers have confirmed that the bioavailability of this microcrystalline form is substantially higher than prior art preparations having larger particles of the carotenoid.
Owner:ZEAVISION LLC

Method for classifying long-distance travel transportation types based on data of mobile phones

ActiveCN106448173AMake up for the lack of high costHigh precisionDetection of traffic movementComputer scienceMobile phone
The invention discloses a method for classifying long-distance travel transportation types based on data of mobile phones. The method comprises the following steps of 1, determining a common class I travel transportation type between a city A and a city B, and obtaining travel information of a volunteer and signaling data of the mobile phone; 2, obtaining a complete track point set T(i) and travel time t(i) of each type of travel path in the class I travel transportation type; 3, extracting a traveler set C between the two cities; 4, obtaining a track point set E(j) of each traveler in the set C; (5) obtaining a travel user set D between the city A and the city B; 6, judging the relationship between the track point set E(j) of each traveler in the set D and the set T(i); under the conditions of formula shown in the attached figure, and unique i value, judging that the j-th traveler adopts the class i transportation type; 7, under the conditions of formula shown in the attached figure, and non-unique i value, calculating the travel time s(j) of the j-th traveler, selecting the travel time, which is most approximate to the travel time s(j), of the corresponding transportation type from the possible value of i value, and using as the transportation type of the j-th traveler. The method has the advantage that the transportation type of the traveler crossing the cities can be accurately identified.
Owner:SOUTHEAST UNIV
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