A digital frequency selection measuring system capable of resisting one hundred thousand times of interference relates to the technical field of measurement. A voltage measurement function front-end circuit of the digital frequency selection measuring system comprises a voltage measuring terminal, an automatic range switching unit, a filter circuit unit and an isolation and amplification unit, a CPU (central processing unit) transmits a signal to control the automatic range switching unit to automatically switch ranges, the automatic range switching unit is connected to the filter circuit unit, the filter circuit unit is connected to the isolation and amplification unit, and output of the isolation and amplification unit is connected to the CPU. A current signal of a current measuring terminal is inputted to an automatic range switching unit, the CPU transmits a signal to control the automatic range switching unit to automatically switch ranges, the automatic range switching unit is connected to a filter unit, the filter unit is connected to an operational amplification unit, the operational amplification unit is connected to the CPU, and the CPU carries out analytic processing. The digital frequency selection measuring system can realize frequency selection measurement with resistance to one hundred thousand times of interference on the basis of +/-1Hz, and has important application in the field of electric measurement, particularly in the field of test of electric systems under the background with high interference.