The invention relates to an electric control and hydraulic integrated type multi-cylinder braking caliper. The electric control and hydraulic integrated type multi-cylinder braking caliper is characterized by comprising a braking caliper body, pistons, a thread sleeve, a screw, an internal braking block assembly, an external braking block assembly, a support, a guiding pin and a bolt. The electriccontrol and hydraulic integrated type multi-cylinder braking caliper belongs to a disc brake, can provide larger braking force, can be applied to a commercial vehicle, and is good in heat dissipationproperty and good in braking efficiency water stability and heat stability; the electric control and hydraulic integrated type multi-cylinder braking caliper has the traveling braking function and the parking braking function simultaneously, can be controlled through an electronic transmission device and a hydraulic transmission device, has the emergency braking function and is reliable and stable in working, compact in structure and easy to arrange; the parking function is electronically controlled so that braking force of the vehicle on different slopes can be automatically adjusted, and the automatic parking function can be achieved; and the adopted thread sleeve is of an integrated double-pressing-head structure, each braking block assembly is provided with two force bearing parts, thus the force bearing area is increased, force bearing is uniform, braking blocks are not liable to tilt, good contact of the braking blocks and a braking disc is ensured, abrasion is balanced, and thus the service life of a brake is prolonged.