The invention provides a large-span grid structure multidirectional bearing and anti-seismic spherical hinge support joint, comprising an upper support, a lower support and a flexible steel bar group.An upper support base is located at the lower end of the upper support, and a lower support supporting seat is located at the upper end of the lower support. The spherical convex face of the upper support base and the spherical concave face of the lower support supporting seat are connected in an embedded fit mode. The upper support and the lower support are connected through the flexible steel bar group. Micro vertical, horizontal and rotary displacements can be allowed, the stability of the structure out of the plane is limited, and the load effects of bearing vertical pressure, stirring force, horizontal force, bending moment, earthquake force, temperature stress and the like are achieved. The structure is used for absorbing and consuming loads caused by earthquakes, the form of support nodes is simplified, good anti-seismic and damping effects on the upper grid structure are achieved, the influence of complex loads on deformation of the lower structure is reduced, and the overallanti-seismic performance of the structure is improved. The manufacturing is simple, the development of an assembly type space structure is promoted, and engineering popularization and application arefacilitated.