The invention discloses a pair of eye-moistening glasses made of a reverse osmosis membrane material. The pair of eye-moistening glasses comprises a glasses frame front body, a reverse osmosis membrane material rear body, an ultrasonic pressure pump, an ultrasonic driving circuit board, a pressure pump shell, a silica gel hose, a driving power supply and glasses legs, and further provides a manufacturing method of the pair of eye-moistening glasses made of the reverse osmosis membrane material. According to the pair of eye-moistening glasses, a method for completely manufacturing a glasses frame through plastic particle injection molding is omitted, and the glasses frame is manufactured by combining the reverse osmosis membrane material rear body and the thin glasses frame, so that the glasses frame has the characteristics of water storage, water retention, slow volatilization, no leakage, attractive appearance, no shielding of left and right sight lines and light frame body; under the cooperation of the ultrasonic vibration pump, the emission rate and concentration of water molecules can be flexibly adjusted, the wet small environment of eyes is improved, dry eyes are relieved, and remarkable effects and a certain application value are achieved; the glasses frame manufactured by the reverse osmosis membrane material rear body and the thin glasses frame can moisten eyes without shielding light and weight on two sides.