The invention discloses a fluffy fiber cotton roll packaging machine, and belongs to the technical field of non-textile machinery. The fluffy fiber cotton roll packaging machine comprises a rack, an actuating mechanism, a screw shaft and a group of pressure claw bars, wherein a group of first pressure claw bar guide rails and a group of second pressure claw bar guide rails are fixed on the rack, a front bearing seat is arranged at the joint center of the group of the first pressure claw bar guide rails, a rear bearing seat is arranged at the joint center of the group of second pressure claw bar guide rails, the actuating mechanism is arranged on the rack, one end of the screw shaft is supported on the front bearing seat, the middle of the screw shaft is supported on the rear bearing seat, the other end of the screw shaft is connected with the actuating mechanism, a connecting rod nut is arranged on the screw shaft in a matched mode, one end of each pressure claw bar is matched with the first pressure claw bar guide rails and further connected with the second pressure claw bar guide rails, the other end of each pressure claw bar extends towards the direction deviated from the rack, each pressure claw bar is connected with one end of each connecting rod in a hinged mode, and the other end of each connecting rod is connected with the connecting rod nut in a hinged mode. The fluffy fiber cotton roll packaging machine has the advantages of being capable of being convenient to transport, saving storage space, relieving operating intensity of workers and ensuring process requirements for follow-up processes such as acupuncture or spunlace.