33 results about "Infective diarrhoea" patented technology

The invention relates to a gene chip and an application, which belongs to the biological detection field. The invention designs a set of detection probes by aiming at 11 types of common infectious diarrheal disease pathogen microorganism in clinic, and the gene chip containing the set of the probe. The detection probes comprises a vibrio parahaemolyticus probe, a vibrio vulnificus, a vibrio cholera probe, a vibrio alginolyticus probe, a vibrio furnissii probe, a shigella probe, an escherichia coli probe, an aeromonas probe, a salmonella probe, a campylobacteria probe, and a proteusbacillus vulgaris probe; the above mentioned probe sequence is shown as SEQ ID No: 1-117. The gene chip and probe can detect 11 types of common infectious diarrheal disease pathogen, the detection flux is high, the specialty is strong, the sensitivity is high, and the detection is rapid and effective.

The invention provides a genetic chip and a detection kit related to major pathogenic microorganisms causing infectious diarrhea of human beings, which are mainly specific to 13 types of bacteria including lapactic bacillus coli/shigella, salmonella, comma bacillus, vibrio parahemolyticus, aeromona hydrophila, plesiomonas, virio hollisae, vibrio fluvialis, vibrio mimicus, Wauter's strains, vibriodamsela and vibrio furnissii. The genetic chip comprises a solid-phase carrier and an oligonucleotide probe fixed on the solid-phase carrier, wherein the oligonucleotide probe comprises DNA (Deoxyribonucleic Acid) fragments selected from genes including a gyrB gene, an ITS gene, a dnaJ gene, a toxR gene and the like with remarkable biological evolution advantages or complementary DNA fragments. By adopting the genetic chip and the detection kit provided by the invention, major pathogenic microorganisms causing infectious diarrhea of human beings can be detected. The genetic chip and the detection kit have the characteristics of easiness and convenience for operation, high flux, high accuracy, high repeatability and the like, and can be applied to clinical detection of inspection departments in hospitals.

The invention discloses an infant formula milk powder for preventing infectious diarrhea, and belongs to the technical field of infant and young children formula milk powder. Each 100 g of the infant formula milk powder contains 250 mg-425 mg of free sialic acid and 30 mg-90 mg of milk fat globule membrane proteins. The invention provides the infant formula milk powder for preventing infectious diarrhea; for solving the risk of occurrence of infant infectious diarrhea, an appropriate amount of the high-quality free sialic acid and an appropriate amount of the milk fat globule membrane proteins are added and play a synergistic effect on preventing the occurrence of infant infectious diarrhea, and the occurrence of infant infectious diarrhea can be prevented.

The invention relates to a primer combination for detecting infectious diarrhea pathogen. The primer combination comprises at least one combination of the following combinations: a rotavirus primer combination, an enteric adenovirus primer combination, a Norovirus primer combination, a salmonella primer combination, a Shigella primer combination and a campylobacter jejuni primer combination. The invention also relates to a kit containing the primer combination. The kit also comprises a primer-coating micro-fluidic chip, an isothermal amplification reaction liquid, an isothermal amplification enzyme solution, and a negative control. The invention also relates to a detection method by using the above primer combination. The detection method comprises steps as follows: coating of the primer combination, nucleic acid extraction of a sample to be detected, LAMP reaction and result interpretation. The kit provided by the invention can detect infectious diarrhea pathogen rapidly and accurately within one hour, and is also of great significance for rapid assisted guide treatment and drug use. The multi-index detection also can be used in regional epidemiological investigation and epidemic surveillance so as to study epidemic situation of infectious diarrhea in China.

The diarrhea treating Chinese medicine composition is prepared with Chinese goldthread, skullcap root, white peony root, patchouly, guava leaf and tuckahoe as material. It has the functions of clearing away heat and toxic material, moisturizing and stopping diarrhea, and can kill diarrhea causing pathogenic bacteria and viruses to cure acute infectious diarrhea in high efficiency, quickly and safely.

The application relates to synthetic compositions containing one or more human milk mono- or oligosaccharides for treating non-infectious diarrhoea.

The invention relates to a umbilical therapy device, which includes an umbilical therapy box, an electric heater and a medicinal magnetic bag lining pad, the umbilical therapy box is used for containing the electric heater and the medicinal magnetic bag lining pad, a medicinal magnetic bag is arranged on the medicinal magnetic bag lining pad, medicine is arranged in the medicinal magnetic bag, the ingredients of the medicine include pricklyash peel, haiercha, fennel fruit, pepper, hedgehog hide, Chinese magnoliavine fruit, dahurian angelica root, round cardamom fruit and magnetite, the medicine is transdermally absorbed and combined with the magnetic therapy and the thermal therapy, the medicine is directly acted on the intestine by passing through the umbilical point, all the ingredients can achieve the effects of warming spleen and stomach, relieving diarrhea with astringents, resolving food, removing expansion and relieving pain; the hot compression performs the effects of warming spleen and stomach, activating collaterals, dispelling cold, stopping pain and promoting telangiectasia; and the magnetic therapy performs the effects of dredging meridians and anti-inflammation. The combination of the three therapies increases the umbilical penetration force of the medicine, the functions of the medicine, the magnet and the heat are overlapped, thereby being applicable to the treatment of non-infectious diarrhea and indigestion of children; compared with the single therapy, the efficacy is improved, the transdermal absorption of the medicine is greatly improved and the treatment effects are improved.

A Chinese medicine for treating the infective or non-infective infantile diarrhea is prepared from 18 Chinese-medicinal materials including pepper, rhubarb, rehmannia root, cinnamon bark, etc. Its advantages are high curative effect, short course of treatment and no toxic by-effect.

The invention discloses a Chinese medicine composition as well as a preparation and application thereof, relates to the field of traditional Chinese medicines and in particularly relates to a Chinese medicine composition for treating infantile diarrhea and a preparation of the Chinese medicine composition. The invention aims at solving the problems in the prior art of limited medicines for treating the infantile diarrhea and toxic and side effects in different degrees and provides the Chinese medicine composition as well as the preparation and the application thereof. The Chinese medicine composition is prepared from the raw materials in parts by weight: 300 parts of fired yam, 150 parts of poria cocos, 100 parts of kudzu, 100 parts of rhizoma atractylodis, 100 parts of dark plum and 50 parts of mangnolia officinalis. The invention also provides the application of the Chinese medicine composition for preparing the medicines for treating non-bacterial infectious infantile diarrhea. The Chinese medicine composition and the preparation have special effects in treating viral enteritis and noninfective diarrhea in the infantile diarrhea.

A Chinese medicine for treating acute, chronic, infective or non-infective diarrhea is prepared from 6 Chinese-medicinal materials including celandine herb, tuckahoe, coix seed, white atractylodes rhizome, etc through immersing, decocting, extracting in alcohol and proportioning.

The invention discloses drug for the treatment of abdominal pain and diarrhea and belongs to the field of TCM. The drug comprises pharmaceutical effective ingredients, including Chinese granesbill, turtle shell, Eryngium foetidum herb, multibract raspberry root, cutch, birch bark, radish seed, Asiatic pennywort herb, common turczaninowia herb, Russian olive fruit, purple flower holly leaf, coastal heritiera seed, chalk, cucubalus root, Yunnan Pistache leaf, and quince. The drug has the effects of regulating qi to alleviate pain, clearing away heat and eliminating dampness, soothing the liver to dispel melancholy and tonifying the spleen to cure diarrhea, and has the significant effect of the diarrhea, watery stool, abdominal pain and poor appetite caused by damp-heat accumulation and the viral enteritis and non-infectious diarrhea caused by rotavirus. The drug has the advantages that the preparation process is simple, curative effect is good and fast, the drug is convenient to take and available for treating both symptoms and root causes, and the drug is neutral in property and has no toxic and side effects; the drug has good effects for the treatment of inappetence, nausea and vomiting, abdominal distension and diarrhea, and dyspepsia.

The invention discloses a cataplasm thermal patch. The cataplasm thermal patch comprises base cloth, wherein a paste layer is arranged on the base cloth, and drug components are arranged on the pastelayer and include the following components in parts by mass: 1-3 parts of raw rhubarb, 6-10 parts of cortex magnoliae officinalis, 6-10 parts of fructus piperis longi, 5-8 parts of fructus evodiae, 3-6 parts of radix aucklandiae, 3-5 parts of schisandra sphnanthera, 3-6 parts of rhizoma picrorhizae, 6-10 parts of rhizoma pinelliae, 3-6 parts of fructus aurantii immaturus, 6-10 parts of galangal, 6-10 parts of fructus chebulae, 3-6 parts of semen myristicae, 1-3 parts of radix sophorae flavescentis and 100-150 parts of deionized water. The cataplasm thermal patch has a specific formula and a reasonable preparation method; the cataplasm thermal patch is suitable for clearing damp, stopping diarrhea, regulating middle warmer and activating spleen and is suitable for treating treat child diarrhea (with the symptoms of diarrhea, thin sloppy or watery stool, abdominal distention, bellyache, anorexia, anabole or fever, pale tongue and white and greasy tongue coat) caused by dampness, encumbering spleen, soil as well as rotavirus enteritis and infectious diarrhea with the syndromes.

A novel K (capsular antigen) serotype of Vibrio parahaemolyticus and an application thereof are provided. A novel K (capsular antigen) serotype of Vibrio parahaemolyticus, which was deposited at the China General Microbiological Culture Collection Center (Institute of Microbiology, Chinese Academy of Sciences, No. 3, Yard 1, Beichen West Road, Chaoyang District, Beijing) on Feb. 20, 2019, with a deposit number of CGMCC No. 17249, wherein the K epitope of the Vibrio parahaemolyticus has a sequence set forth in Sequence No. 1. The novel K serum is highly specific, and can be used to conveniently and quickly detect a novel K serotype of Vibrio parahaemolyticus (O4:KUT-recAin) which has a rising infection rate in recent years. It provides important detection techniques for the pathogen diagnosis, monitoring and prevention of infectious diarrhea.

The invention discloses a patch for children. The patch for children comprises the following raw materials in parts by weight: 30-35 parts of clove, 20-25 parts of cinnamon, 12-15 parts of fructus piperis longi, 5-8 parts of radix curcumae longae, 7-12 parts of golden cypress, 3-5 parts of rheum officinale, 2-5 parts of radix angelicae and 4-8 parts of pericarpium citri reticulatae. The invention also discloses a preparation method of the patch for children. The method comprises the following steps: crushing the radix curcumae longae and the golden cypress into crude powder; filtering by a 120-140mesh sieve to obtain fine powder of the radix curcumae longae and the golden cypress; adding 8-10fold of 65-75% ethanol, heating to 60-70 DEG C, and carrying out reflux extraction for 1-3 times; filtering and merging filtrate, and then concentrating into thick paste; mashing the clove, the cinnamon, the fructus piperis longi, the radix curcumae longae and the pericarpium citri reticulatae and then grinding into powder; adding the powder to the thick paste; spraying rheum officinale juice; heating to 70-80 DEG C, so as to obtain the patch. The patch can be independently applied to treatment of noninfectious diarrhea in children caused by cold, dyspepsia and the like. The effective components in the patch, such as the clove and the cinnamon can be used for tonifying the spleen and warming the middle warmer, and dispelling cold and stopping diarrhea. Therefore, the patch is convenient to use.

The invention discloses a patch for children with acute diarrhea. The patch for children with acute diarrhea comprises the following raw materials: root of chinese barberry, coptis chinensis, golden cypress, gallnut, fresh ginger, agastache rugosus and rhizoma atractylodis. The invention discloses a method for preparing the patch for children with acute diarrhea. The method comprises the following steps: cutting the root of Chinese barberry, the coptis chinensis and the golden cypress into small segments; adding 5-8fold water, heating to 60-70 DEG C, and carrying out reflux extraction once; filtering to obtain filtrate; adding an ethanol solution to filter residues; carrying out reflux extraction once, and filtering to obtain filtrate; merging filtrate of twice for later use; putting the gallnut, the fresh ginger, the agastache rugosus and the rhizoma atractylodis into a steam box to steam, wherein the temperature achieves 95-100 DEG C, and the time is 2-3 hours; repeatedly steaming for 2-3 times; finally collecting water vapor; adding to a concentrating pot to concentrate at high temperature after merging the filtrate with water vapor to obtain the patch body. The patch can be independently applied to treatment of noninfectious diarrhea in children caused by cold and dyspepsia, the effective components in the patch, such as the coptis chinensis and the golden cypress can be used for tonifying the spleen and warming the middle warmer, and dispelling cold and stopping diarrhea, and the gallnut can be used for astringing the lung. Therefore, the patch is good in effect.

The invention belongs to the technical field of Chinese herba preparation, in particular relates to a traditional Chinese medicine composition for treating infantile diarrhea, and further discloses a preparation method thereof. The traditional Chinese medicine composition for treating infantile diarrhea provided by the invention is prepared from the following crude drugs: fructus piperis alba, poria cocos, the fruit of Chinese magnoliavine, fruit of immature citron, herba houttuyniae, fructus psoraleae, the root of kudzu vine, rhizoma corydalis, frankincense, rhizoma alismatis, honeysuckle stem, fructus citrus sarcodactylis and chastetree fruit. The crude drugs are combined to achieve the effect, so that the traditional Chinese medicine composition for treating infantile diarrhea has higher effective rate on treating infantile diarrhea, is effective in treatment of bacterial diarrhea, viral diarrhea, non-infectious diarrhea and other infantile diarrhea, does not need expensive recovery cost, and is shorter in treatment cycle and convenient to popularize clinically in large scale.

The present synergistic herbal compositions comprising herbal ingredients extracted from at least two herbal species selected from the group consisting of Ocimum basilicum, Agathosma betulina, Cinnamomum cassia, Cinnamomum verum and Apium graveolens helps maintain the electrolyte and fluid balance by exerting its inhibitory secretory activity and by increasing the absorptive capacity of the intestine to prevent dehydration during an episode of infectious and non-infectious diarrhoea and in dehydration associated with various clinical and non-clinical conditions