The invention provides a nuclear power plant area security method. The method comprises steps: a drone conducts inspection on the nuclear power plant area, peripheral person and surrounding environment images of the nuclear power plant area are photographed, own position coordinates are also acquired, and the images and the own position coordinates are transmitted to a command center; the commandcenter performs person image comparison, after the person is determined to be an outside person, comparison among the surrounding environment image photographed by the drone, the drone position coordinates, a warning area boundary identification line position and an environment image is carried out, the current intrusion behavior and the previous intrusion record of the outside person are determined, and in preset warning levels and corresponding security strategies, the warning level triggered by the outside person currently is obtained, the corresponding security strategy is started and executed to stop intentional invasion or destruction of the outside person. When the method and the system are executed, on the basis of not increasing manpower input, multi-dimensional, low-blind area and high-efficiency novel security is formed, the nuclear power plant warning efficiency can be effectively enhanced, and the possibility of deliberate intrusion or destruction by persons can be reduced.