21 results about "Phenothiazine derivative" patented technology

The invention provides a diaphragm and a secondary battery, and belongs to the technical field of secondary batteries, and the diaphragm comprises a base membrane and a coating. Wherein the coating is arranged on one surface, facing the positive pole piece, of the base film, and the coating comprises an electroactive material and a binder; the electroactive material comprises at least one of a quinone derivative, a phenazine derivative, an imide derivative and a phenothiazine derivative. The electroactive material in the diaphragm coating can be dissolved in the electrolyte after the environment temperature reaches the thermal safety critical temperature, and reacts with the positive and negative active materials, so that the charge state of the battery is quickly reduced, and the thermal runaway of the battery is inhibited or even avoided.

The invention belongs to the technical field of pesticides and plant disease control, and provides an antifungal phenothiazine derivative which can inhibit various fungal diseases on rice and tobacco. The derivative can also be compounded with triazole or fluazinam to prevent and treat fungal diseases of rice and tobacco, and has a good development prospect.

The invention discloses a method for constructing a self-assembled monomolecular layer based on phenothiazine heterocyclic compounds and preparing a perovskite solar cell, and belongs to the technical field of perovskite solar cells. According to the method, phenothiazine derivatives are used between a hole transport layer and a perovskite layer, so that the phenothiazine derivatives have the functions of promoting charge transport, improving the hole extraction rate, modifying a buried interface and promoting perovskite growth. The modified perovskite buried layer is obtained by spin-coating a phenothiazine derivative solution on the surface of nickel oxide. The phenothiazine derivative can optimize the energy level arrangement, improve the coverage uniformity, promote the subsequent crystallization and growth of perovskite, and contribute to the generation of a high-quality perovskite thin film. Meanwhile, the method can effectively reduce the cell efficiency loss caused by perovskite defects, and finally obtains an efficient and stable perovskite solar cell device.

The application relates to a synthesis method of a phenothiazine derivative, and belongs to the technical field of synthesis in organic chemistry. A diaryl iodonium salt and N-(2-mercapto phenyl)-4-methyl benzene sulfonamide are used as starting materials, and chlorpromazine and perphenazine are obtained through a plurality of steps of substitution reaction, reduction reaction, addition reaction and deprotection reaction. In the application, the reaction raw materials are easy to obtain, the yield is high, and chlorpromazine and perphenazine can be successfully obtained.

A phenothiazine derivative compound represented by general formula [I] is used as an antioxidant. The problems of poor appearance caused by surface migration of the antioxidant, pollution of other parts in contact with a formed part, volatilization or dissolution of the antioxidant to the external environment, extraction caused by liquid media such as grease or organic solvents and the like can be prevented; therefore, safe utilization and long service life of the rubber molded part in various use environments are possible. In general formula [I], R1 is a monovalent aliphatic hydrocarbon group having 1-10 carbon atoms, R2 is a divalent aliphatic hydrocarbon group having 1-5 carbon atoms, and n is 0 or an integer of 1-6.

A kind of boron-nitrogen phenothiazine piezochromic material and preparation method thereof, relate to the technical field of color-changing material, with substituted phenothiazine derivative and dimethyl boron fluoride as raw material, boron-nitrogen phenothiazine structure piezochromic material is obtained by reaction.The beneficial effects of the present application are that the material provided by the present application has high contrast color change under the action of external force, the maximum spectrum can be moved by 106nm, can be applied to information storage, reversible writing medium, sensing and anti-counterfeiting and other fields, and can also be applied to fluoride ion detection.

The invention discloses a polymer-based long-afterglow luminescent material as well as a preparation method and application thereof, and belongs to the field of organic luminescent materials. The polymer-based long-afterglow luminescent material is a host-guest doped material of an organic small molecule guest based on a benzo [b] phenothiazine derivative and a host of polymethyl methacrylate. The macroscopic afterglow time of the obtained long-afterglow luminescent material can reach the hour level. The obtained material has excellent machinability, transparency and flexibility, and can be used in the fields of environment-friendly illumination, advanced anti-counterfeiting, information encryption, 3D printing, biological imaging and the like.

According to the invention, structural characteristics and characteristic functions of imino polyphosphonic acid, phenoxazine or phenothiazine are combined, phenoxazine or phenothiazine, p-halonitrobenzene and vinyl phosphonate are taken as main raw materials, and a diphosphonic acid phenoxazine derivative or a diphosphonic acid phenothiazine derivative is created. The bisphosphonated phenoxazine derivative or the bisphosphonated phenothiazine derivative has the property of absorbing ultraviolet rays and the function of converting the ultraviolet rays, has good solubility in an aqueous solution and a small molecular alcohol solvent, and is suitable for a photo-electromagnetic stimulation-response hydrogel material and an organic small molecular SAM hole transport material of a perovskite solar cell.

The application belongs to the field of electrochromic materials, and relates to a preparation method of a colorless-orange red reversible switching electrochromic material based on phenothiazine. The method comprises the following steps: functionalization of a phenothiazine small molecule, introduction of a polymerizable functional group on the phenothiazine structure, ring-opening polymerization of a phenothiazine derivative, dehydration of a cyclization polymerization intermediate, and preparation of an electrochromic material. The conjugated electron-rich structure of phenothiazine makes it have an advantage as an electroactive group of an electrochromic material. In addition, the multiple active sites provide advantages for the synthesis of polymer structure regulation. The application introduces a non-coplanar propeller configuration and a polymerization monomer into the phenothiazine skeleton through a synthesis reaction, and the electrochromic film prepared after polymerization has electrochromic characteristics such as colorless-orange red reversible switching and good stability, and has great application potential in the fields of smart windows, camouflage materials and the like.

The invention belongs to the technical field of medicines, and particularly relates to an alpha-lipoic acid phenothiazine derivative as well as a preparation method and application thereof. The structural formula of the alpha-lipoic acid phenothiazine derivative is as shown in formula 1. The invention provides an alpha-lipoic acid phenothiazine derivative, and research finds that the alpha-lipoic acid phenothiazine derivative shows good anti-inflammatory activity which is slightly superior to that of alpha-lipoic acid. Moreover, the effect of the pharmaceutical composition is better than that of a positive drug edaravone clinically used in cerebral arterial thrombosis at present, and the pharmaceutical composition can be further developed into a treatment drug applied to ferroptosis related diseases. .

The invention provides a boron-nitrogen compound and an organic electroluminescent device using the same, and relates to the technical field of organic electroluminescence. The boron-nitrogen compound provided by the invention has high color purity and high reverse intersystem crossing rate. A rigid group is introduced to a central benzene ring, so that the molecular vibration relaxation is reduced, the FWHM is reduced, and the color purity is improved; meanwhile, derivative donors containing heteroatom phenoxazine or phenothiazine and the like are introduced, spin-orbit coupling is promoted by utilizing a heavy atom effect, so that the reverse intersystem crossing rate of excitons from a triplet state to a singlet state is increased, and the triplet state exciton extinguishing process is weakened. In addition, a large-volume peripheral substituent group is introduced to inhibit aggregation among molecules, so that a mutual quenching phenomenon among the molecules is weakened, and the luminous efficiency is improved. Therefore, when the compound is applied to the organic electroluminescent device, the color purity and luminous efficiency of the organic electroluminescent device can be improved.

The invention provides a preparation method of an organic-inorganic hybrid perovskite solar cell based on phenothiazine derivative molecules and organic phosphoric acid small molecules. The preparation method comprises the following steps: S1, preparing an inorganic hole transport layer; s2, spin-coating the hole transport layer with an isopropanol solution of first organic phosphonic acid micromolecules, and annealing to form an intermediate layer; s3, mixing an isopropanol solution of phenothiazine derivative molecules and an isopropanol solution of second organic phosphoric acid small molecules, spin-coating the intermediate layer, and annealing to form a self-assembled monomolecular layer; s4, spin-coating the perovskite precursor solution on the self-assembled monomolecular layer, and annealing to form a perovskite active layer; s5, preparing an electron transport layer; and S6, preparing the organic-inorganic hybrid perovskite solar cell. According to the perovskite solar cell, phenothiazine derivative molecules and organic phosphoric acid small molecules are synergistically mixed to prepare the hole transport layer, energy level matching between the ITO electrode and the perovskite active layer is effectively regulated and controlled, and the photoelectric conversion efficiency and long-term stability of the perovskite solar cell are improved.

The application discloses a kind of phenthiazine-based two-dimensional covalent organic framework materials constructed by supramolecular inclusion complex and application thereof, belong to the field of biological medicine.The phenthiazine-based two-dimensional covalent organic framework material takes 4,4',4'',4'''-(anthracene-9,10-diylbis(10H-phenthiazine-10,3,7-triyl)) tetrakisbenzaldehyde and beta-CD dithylamine inclusion complex as structural unit, and is obtained by solvothermal reaction two-dimensional crystalline porous copolymer.The application utilizes supramolecular inclusion complex and copolymerization of phenthiazine derivative and beta-CD dithylamine to obtain PTz-CD-COF with negligible biological toxicity, the material can also realize the synergistic effect of photodynamic therapy and photothermal therapy simultaneously, and cyclodextrin forms "PDT-PTT-cyclodextrin mediated synergistic" multi-component synergistic treatment system through its unique molecular recognition and inclusion effect.

Provided is a method for using a phenothiazine derivative compound, in which, in a synthetic polymer material produced by addition polymerization of a polymerizable unsaturated monomer, the polymerizable unsaturated monomer constituting the material is copolymerized with a phenothiazine derivative compound represented by general formula [I] in order to prevent oxidative degradation of the synthetic polymer material. The compound can be copolymerized with various polymerizable unsaturated monomers because the specific polymerization inhibition effect of the phenothiazine compound is reduced. In the general formula [I], R1 is a monovalent aliphatic hydrocarbon group having 1-10 carbon atoms, and R2 is a hydrogen atom or a methyl group.

A phenothiazine derivative represented by the general formula:(wherein R1 is a monovalent aliphatic hydrocarbon group having 1 to 20 carbon atoms or an aralkyl group having 7 to 20 carbon atoms, and R2·Ar is an aralkyl group, wherein R2 is a divalent aliphatic hydrocarbon group having 1 to 10 carbon atoms, and Ar is a monovalent aromatic hydrocarbon group having 6 to 10 carbon atoms), anda carboxyl group-containing acrylic rubber composition comprising, based on 100 parts by weight of carboxyl group-containing acrylic rubber:(A) 0.1 to 5 parts by weight of the phenothiazine derivative represented by the formula [I];(B) 0.1 to 3 parts by weight of a crosslinking agent for carboxyl group-containing acrylic rubber; and(C) 0.1 to 5 parts by weight of a crosslinking accelerator for carboxyl group-containing acrylic rubber.

The invention belongs to the technical field of preparation of high-sensitivity fluorescent probes, and provides a preparation method of a cucurbit [7] urea-phenothiazine derivative fluorescent probe and application of the cucurbit [7] urea-phenothiazine derivative fluorescent probe in hypochlorite detection, and the preparation method comprises the following steps: mixing a cucurbit [7] urea solution, a phenothiazine derivative solution and water to obtain a fluorescent probe solution, namely the fluorescent probe. Compared with traditional instrumental analysis and detection methods such as high performance liquid chromatography and gas chromatography, the method has the advantages that sample treatment is simple, detection is convenient, real-time detection can be achieved, and the detection cost is greatly reduced. The probe can detect hypochlorite in a solution, the detection limit can reach 8.5 * 10 <-8 > mol / L, highly selective detection of hypochlorite by a single probe can be achieved, and the beneficial effects of rapid determination and real-time detection can be achieved.

The invention discloses a fluorescent probe compound taking a phenothiazine derivative modified by polyarylimidazole as a core structure as well as a preparation method and application of the fluorescent probe compound, and belongs to the technical field of fluorescent probes. The invention aims to solve the problem that the existing HClO / ClO-detection method generally has higher detection limit and complicated procedures. The preparation method comprises the following steps: taking 10-butyl-10H-phenothiazine-3-formaldehyde, 4, 4 '-dibromobenzene, ammonium acetate and aniline as raw materials, carrying out cyclization reaction to synthesize an intermediate PI-Br, and then carrying out Suzuki coupling reaction on the intermediate PI-Br and arylboronic acid containing electron donating or electron withdrawing substituent groups to obtain target probe compounds PI-Ph, PI-Ph-OCH3, PI-Ph-CH3, PI-Ph-CN and PI-Ph-CHO. As a fluorescent probe compound, the compound has the characteristics of high selectivity, low detection limit, capability of identifying color change by naked eyes and the like on HClO / ClO-, can sensitively and intuitively detect HClO / ClO-through optical signal change, and is particularly suitable for detection requirements of a complex water sample system. According to the invention, the probe compound PI-Ph-CN is prepared into a fluorescent test strip, a convenient field detection device is constructed, and real-time nondestructive determination of HClO / ClO-in a water sample is realized.

The present invention relates to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathies, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to the use of novel classes of compounds, i.e. inhibitors of RSK (p90S6K); inhibitors of p70S6K; and inhibitors of rps6, to treat ribosomal disorders and ribosomopathies. In some embodiments, the invention relates to the use of specific Chk2 inhibitors and to the use of specific phenothiazine derivatives to treat ribosomal disorders and ribosomopathies, e.g. DBA.

The invention discloses a positive electrode electrolyte and a flow battery, the positive electrode electrolyte comprises a positive electrode electrolyte, and the positive electrode electrolyte is selected from at least one of phenothiazine derivatives. The phenothiazine derivative disclosed by the invention has excellent redox reversibility, electrochemical stability and high solubility, shows excellent cycle stability when being applied to aqueous organic flow batteries, and is a very promising positive active molecule.

The invention discloses a phenothiazinyl two-dimensional covalent organic framework material constructed by utilizing supramolecular inclusion complexation and application of the phenothiazinyl two-dimensional covalent organic framework material, and belongs to the technical field of biological medicines. According to the phenothiazinyl two-dimensional covalent organic framework material, 4, 4 ', 4', 4 ''-(anthracene-9, 10-diyl bis (10H-phenothiazin-10, 3, 7-triyl)) tetrabenzaldehyde and a beta-CD benzidine inclusion compound are used as structural units, and a two-dimensional crystalline porous copolymer is obtained through a solvothermal reaction. According to the invention, phenothiazine derivatives and beta-CD benzidine are copolymerized by utilizing supramolecular inclusion complexation to obtain PTz-CD-COF with negligible biotoxicity, and the material can synchronously realize the synergistic effect of photodynamic therapy and photothermal therapy; and a PDT-PTT-cyclodextrin mediated synergistic multi-element synergistic treatment system is formed.

By using a phenothiazine-based derivative compound represented by a general formula (R1 is a monovalent aliphatic hydrocarbon group having 1-10 carbon atoms, R2 is a divalent aliphatic hydrocarbon group having 1-5 carbon atoms, and n is 0 or an integer between 1 and 6) as an antioxidant, it is possible to prevent problems such as appearance defects caused by migration of the antioxidant to a surface, contamination of other members that come into contact with a molding member, volatilization or elution of the antioxidant into an external environment, and extraction by liquid media such as oils / fats and organic solvents, and enable safe use and a longer working life of rubber molded members in a variety of usage environments.