89 results about "Electromagnetic stimulation" patented technology

An electromagnetic stimulation device which is comprised of a plurality of overlapping coils which are able to be independently energized in a predetermined sequence such that each coil will generate its own independent electromagnetic field and significantly increase the adjacent field. The coils are co-planar and are disposed in an ergonomic body wrap, which is properly marked to permit an unskilled patient to locate the body wrap, on a particular part of the body, of the patient so that the stimulation coils will maximize the electromagnetic stimulation on the selected nerves, muscles, and / or body tissues near the treated area. The device can be used to treat medical conditions including: muscular atrophy, neuropathic bladder and bowel, musculoskeletal pain, arthritis, as well as possible future applications in the prevention of deep vein thrombosis and weight reduction.

An electromagnet coil comprising Litz wire windings and power leads without break or interruption is cooled by a perfluorinated liquid by sensible and phase change heat transfer in a closed system. The electromagnet coil may be housed in a pentagonal or hexagonal pressure vessel to allow high packing densities in an array or helmet configuration. The helmet is then lowered over a human cranium for transcranial electromagnetic stimulation. The Litz wire windings reduce the power and voltages required for operation, yet allow production of over 2 T of accurately directed magnetic pulses for direct nerve or neuron stimulation. The perfluorinated liquid maintains the temperature of the helmet to less than 35-40° C., ensuring a comfortable temperature device for a human test subject. A utility cable connects the helmet to an external cooling unit and an external power supply.

An electromagnetic stimulation device which is comprised of a plurality of overlapping coils which are able to be independently energized in a predetermined sequence such that each coil will generate its own independent electromagnetic field and significantly increase the adjacent field. The coils are co-planar and are disposed in an ergonomic body wrap, which is properly marked to permit an unskilled patient to locate the body wrap, on a particular part of the body, of the patient so that the stimulation coils will maximize the electromagnetic stimulation on the selected nerves, muscles, and / or body tissues near the treated area. The device can be used to treat medical conditions including: muscular atrophy, neuropathic bladder and bowel, musculoskeletal pain, arthritis, as well as possible future applications in the prevention of deep vein thrombosis and weight reduction.

Methods, devices and systems for Transcranial Magnetic Stimulation (TMS) are provided for synchronous, asynchronous, or independent triggering the firing multiple of electromagnets from either a single power source or multiple energy sources. These methods are particularly useful for stimulation of deep (e.g., sub-cortical) brain regions, or for stimulation of multiple brain regions, since controlled magnetic pulses reaching the deep target location may combine to form a patterned pulse train that activates the desired volume of target tissue. Furthermore, the methods, devices and systems described herein may be used to control the rate of firing of action potentials in one or more brain regions, such as slow or fast rate rTMS. For example, described herein are multiple electromagnetic stimulation sources, each of which are activated independently to create a cumulative effect at the intersections of the electromagnetic stimulation trajectories, typically by means of a computerized calculation.

The present invention relates to a novel method and device for electromagnetic stimulation of the skin for the purpose of modifying a physiological condition or performing treatment of a given pathology, and also to an electronic device enabling said method to be implemented. The device is characterized in that it comprises electronic elements imparting oscillatory behavior thereto at at least one resonant frequency, said resonance being induced by electromagnetic induction external to the device. A particular embodiment of the device is a passive electronic circuit that does not include any source of energy, characterized in that it comprises in series a self-inductor (1), a capacitor (2), and a resistor (3).

Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and / or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and / or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and / or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and / or electrophereis can also be used with the disrupting agents.

Current treatment options for Overactive Bladder and Urinary Incontinence include exercise and behavioral modifications, pharmacological therapies, surgical intervention, and neuromodulation. Although each of these treatments is used in the treatment of individuals with these conditions, each has severe limitations. Building on the limitations of existing therapies, and with the distillation of lessons learned from the field of pulsed electric stimulation, the present invention employs Low Frequency Induction Therapy for the delivery of an effective, cost efficient, noninvasive alternative to available treatment options. The device of the present application allows for consistent, user-friendly modulation of the pudendal nerve and the sacral plexus, via pulsed electromagnetic stimulation of the posterior tibial nerve, on an outpatient basis. The device has two primary components: a programmable Logic Controller (LC), which generates the required current, and a Conductive Wrap (CW), through which the current is channeled in generating the pulsed electromagnetic fields.

A body orifice remodeling device includes a cylindrical handpiece having a defined length which is adapted to be inserted into the body orifice and an elongated monopolar electrode mounted outside on the circumference of the cylindrical handpiece and extending substantially along the length of the handpiece. A source of radio frequency (RF) energy in the handpiece is configured to generate RF energy to the elongated monopolar electrode; and a source of electromagnetic stimulation energy (EMagS) in the handpiece is configured to generate (EMagS) energy.

A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.

A method for differentiating mesenchymal stem cells (MSCs) towards osteoblasts and other connective tissue using nanoparticles and electromagnetic stimulation Osteoinductive materials produced using said method may be useful for bone regeneration and reconstruction in treatment of bone trauma and bone related diseases, and to correct birth defects.

Methods of enhancing cell proliferation in tissue cultures and at the site of tissue defects in human or other animal subjects, comprising the steps of: (a) culturing a living tissue in a medium to form a tissue culture; (b) subjecting said tissue culture to an electromagnetic field; (c) extracting said medium from said tissue culture; and (d) administering said medium to the site of said tissue defect. Preferably, the tissue culture comprises endothelial cells. The present invention also provides compositions for the treatment of tissue defects in a human or other animal subject, comprising a safe and effective amount of a medium produced by electromagnetic stimulation of a tissue culture. Preferably, the compositions comprise a pharmaceutically acceptable carrier, such as hyaluronic acid, gelatin, collagen, cellulose ether, and osteoconductive carriers.

A system for controlling and modulating a mammalian's body temperature and thermoregulation system includes: a. a display monitor; b. a pulse generator; c. at least one channel of electrical or electromagnetic stimuli connected to the pulse generator, and adapted for cutaneous application on the body's spinal cord; d. a control panel, and e. at least one Measurement Analysis and Command (MAC) unit. The control panel and the MAC units are adapted to implement the optimal stimulating procedure for blocking the afferent neural pathways, evoking the afferent neural pathways, attenuating the afferent neural pathways, blocking and evoking the efferent neural pathways, blocking and attenuating the efferent neural pathways, attenuating and evoking, or blocking, attenuating, and evoking the efferent neural pathways, involved in the thermoregulation system, thereby controlling and modulating the body's temperature and thermoregulation system.

A modular, multi-modal energy therapy system for electrical and electromagnetic stimulation includes signal generating, conditioning, and control electronics, stimulation monitoring electronics, signal conduits, and wearable energy emitter modules configured for coupling energy emitters to surfaces of the human ear for transcutaneous energy delivery to nerves in the auricular nerve field. Electrical emitter modules configured with electrodes deliver electrical stimulation; electromagnetic emitter modules configured with light emitting diodes deliver electromagnetic stimulation. A computer controls signal generating electronics and provides internet connectivity with a remote server. Application software includes stimulation programming and parameter selection, and databases containing user data, records of stimulation sessions, user responses to symptom assessment instruments, and biofeedback sensor input enable local and remote monitoring of a user's health status by therapists.

The electromagnetic stimulation device contains at least a positive electrode and at least a negative electrode. An insulating gap having width of a first distance is maintained between the positive and negative electrodes. The positive and negative electrodes are at least at a second distance away from a nerve to be stimulated. A preset voltage is applied to the positive and negative electrodes so that a low-power, low-temperature, high-frequency electromagnetic field covering and stimulating the nerve is produced between the positive and negative electrodes. By the stimulation of the low-power, low-temperature, high-frequency electromagnetic field, the nerve's threshold is increased, the nerve's transmission capability is reduced, and therefore the nerve pain is effectively eased.

Disclosed are devices, methods, and systems for helping to prevent (or preventing) or treat brain and / or body disorders. Embodiments of the invention have utility for enhancing cognitive function during aging. The invention utilizes electromagnetic stimulation (EMS) that can provide a range of EMS parameters and modalities. The EMS may be utilized in conjunction with physiologic sensors that can provide feedback for possible EMS modifications.

Plasmonics-active metal nanostars are provided that can be used for treating and detecting cells in a subject. The modes of treatment include a photo-activated drug, which is activated by the photo-response of the nanostar to electromagnetic stimulation; a thermally-activated drug, which is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which may directly or indirectly cause the death of an undesirable cell. Uptake of nanostars by undesirable cells may also aid in detection, by enhancing contrast or otherwise transforming electromagnetic stimulation during imaging.

The invention provides a finished automobile electromagnetic stimulation reverse modeling method. The method includes the following steps that views in various directions are obtained according to shot pictures of an automobile body, modeling software is imported, a curved surface partitioning technology is utilized to divide the finished automobile body into curved surface blocks with continuous curvatures , and all the curved surface blocks are spliced and sewn to form a finished automobile model; the finished automobile model is simplified; mesh generation is conducted on the simplified model; the generated finished automobile mesh model is imported into the electromagnetic stimulation software for conducting stimulation analysis on finished automobile electromagnetic performance. According to the finished automobile electromagnetic stimulation reverse modeling method, the finished automobile electromagnetic stimulation model is established under the condition that a sample automobile is possessed, so that automobile electromagnetic performance stimulation analysis operation does not need to depend on finished automobile original automobile data any longer; when the finished automobile original automobile data are not available, expensive three-coordinate scanning does not need to be conducted on the sample automobile, the pictures obtained by simple and feasible shooting are used as data sources for conducting reverse modeling, on the premise that accuracy of the model is guaranteed, cost of finished automobile reverse modeling is greatly reduced, the modeling workload is effectively reduced, and time needed for modeling is effectively shortened.

The invention relates to a preparation method of the intelligent self-lubricating composite material containing the electromagnetic trigger microcapsules. The intelligent self-lubricating composite material comprises a conductive polymer matrix and the electromagnetic trigger microcapsules. According to the invention, the release of core-material active substances by the microcapsules are remotelyregulated and controlled through external electromagnetic stimulation, and self-repairing of lubrication and corrosion resistance of the conductive polymer composite material is realized. Compared with existing self-lubricating composite materials, the composite material provided by the invention has continuously variable electric current and magnetic field intensity which are triggered by electromagnetic stimulation, so that tunable stimulation response is realized. The intelligent composite material system and a self-repairing / self lubricating strategy thereof provided by the invention havelarge application potential and market value in the fields of self-lubricating bearings, anti-corrosion coatings, battery electrode materials and the like.

Device for applying an electromagnetic field for stimulation of a process within a living organism when applied to at least part of a body, comprising a driver for generating a time varying drive signal and a transducer responsive to said drive signal for generating a time varying electromagnetic field signal B(t). The signal B(t) comprises a superposition of two or more periodic base signals bi(t) (i=1, 2, 3, . . . ). The signal bi(t) is defined as: bi(t)=ai*(2exp(−ωit)−(1+exp(−ωiTi / 2)) for 0≦t≦Ti / 2 and bi(t)=−bi(t−Ti / 2) for Ti / 2≦t≦Ti, wherein Ti is the period of bi(t), ai is an amplitude of bi(t) and wi is a characteristic frequency determining the shape of the signal bi(t).

A method of determining a pore characteristic, a method of preparing a sample unit, and a sample unit are provided. In the method of determining, a sample is subjected to an external magnetic field, the sample including a porous substance and a medium including a confined portion confined into the pores of the porous substance and a bulk portion surrounding at least a portion of the porous substance, the sample further including probe gas soluble to the medium and inert to the medium and to the porous substance and having a nuclear magnetic response to electromagnetic stimulation, the nuclear magnetic response depending on the magnetic environment of the probe gas, at least a portion of the probe gas being confined to the pores and being transferred into the pores as dissolved in the confined portion, the medium being selected to generate a magnetic environment for the probe gas confined to the pores that differs from the magnetic environment of the probe gas dissolved in the bulk portion; electromagnetic stimulation is applied to the sample, the electromagnetic stimulation being selected to induce at least one response signal in the probe gas; the at least one response signal is recorded; and the pore characteristic is determined from the at least one response signal.

The invention discloses a brain function rehabilitation assisting device based on bioelectrical feedback, comprising a brain wave monitoring module, a transcranial stimulation module and a data exchange module, wherein the brain wave monitoring module is arranged to collecting brain wave signals of a user, extract features of the signals, and monitor whether the signals are normal, the transcranial stimulation module is arranged to generate electromagnetic stimulation signals according to abnormal brain wave signals, the data exchange module is arranged to realize data exchange between the brain wave monitoring module and the transcranial stimulation module, the transcranial stimulation module comprises an electrotherapeutic / magnetotherapeutic unit, a PCM (Pulse Code Modulation) encoder, a PCM decoder and a digital-to-analog converter, the electrotherapeutic / magnetotherapeutic unit comprises at least two electrodes and at least one magnetic pole, the PCM encoder is arranged to encode waveforms outputted from each electrode to obtain a PCM-encoded waveform file, the PCM decoder is arranged to decode waveform data and true values of the respective electrodes, and the digital-to-analog converter is arranged to convert the true values into control signals, switch polarities of the electrodes, and convert the waveform data into current signals which are outputted through the electrodes. The brain function rehabilitation assisting device based on the bioelectrical feedback disclosed by the invention realizes the programmed real-time control on polarities of the electrodes for transcranial stimulation, and has a very good prospect for remote applications.

The invention relates to the dental restoration field, especially to an electromagnetic stimulation dental implantation device, which includes an implant and a healing abutment movably connected to the implant. The healing abutment is an annular hollow shell, the healing abutment cavity is internally provided with an electromagnetic generator, which can generate an electromagnetic field stimulating the growth and healing of bone tissue around the implant under a power-up state. The electromagnetic generator in the healing abutment provided by the invention can generate a low frequency electromagnetic field under a power-up state, can effectively promote increment, differentiation and calcium salt absorption of damaged bone tissue osteoblasts around the implant, thus speeding up the growth and healing of the injured bone tissue, shortening the healing period, and alleviating the pain of patients.

The invention relates to a probe for deep brain electromagnetic coupling stimulation and electric signal detection, and belongs to the technical field of infrared / terahertz. The probe comprises a probe tubular structure and a probe end seal. The probe tubular structure is sequentially composed of a probe shell, a polycarbonate insulating sleeve layer, a brass sleeve layer, a polycarbonate base layer, a silver film and a silver iodide film from the outer side to the inner side. The brass sleeve layer extends out of the probe tubular structure to form a probe tip; an optical fiber lens is embedded in the probe tip; and the tip of the probe tip is sealed with cycloolefin resin. The probe provided by the invention not only can couple a high-frequency electromagnetic signal into a specific target in the brain of a higher animal, but also can cling to nerve cells of the target to carry out real-time electric signal detection on the stimulation effect. The deep brain electromagnetic stimulation probe can provide an efficient, minimally invasive and high-targeting stimulation mode and can accurately detect the action potential of a functional area to finally achieve more effective deep brain electromagnetic stimulation and detection.

The present invention provides methods to modify the genetic regulation of mammalian tissue, bone, cells or any combination thereof by preferential activation, up-regulation and / or down-regulation. The method comprises steps of tuning the predetermined profiles of one or more time-varying stimulation fields by manipulating the B-Field magnitude, rising slew rate, rise time, falling slew rate, fall time, frequency, wavelength, and duty cycle, and exposing mammalian cells or tissues to one or more tuned time-varying stimulation fields with predetermined profiles. Examples of mammalian cells or tissues are chondrocytes, osteoblasts, osteocytes, osteoclasts, nucleus pulposus, associated tissue, or any combination. The resulted modification on gene regulation of these cells, tissues or bones may promote the retention, repair of and reduction of compromised mammalian cartilage, bone, and associated tissue.

A distributed electromagnetic coil structure for applying a time varying electromagnetic field to a population of living organisms is described. The coil structure comprises at least a substantially planar first coil sub-structure. The first coil sub-structure comprises at least a first wire of a predetermined shape and a least a second wire of a predetermined shape, wherein said first and second wire are shaped to define one or more of first cells. An electromagnetic field is generated by said first cells when a current runs through said first coil sub-structure.