Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

32 results about "Electromagnetic stimulation" patented technology

Electromagnetic Therapy produces gentle, low induction impulses which help to stimulate and rejuvenate the cells in the body. This can lead to improved health and well-being. The treatment stimulates the production of nitrogen monoxide within the body which leads to better blood supply and circulation.

Multi-mode physiotherapy system integrating ion release and electromagnetic stimulation

The invention relates to the technical field of physiotherapy, in particular to a multi-mode physiotherapy system integrating ion release and electromagnetic stimulation. The system comprises a biological feedback sensing module, an intelligent control module, a space-time cooperative control module, a multi-channel ion release module, a multi-band electromagnetic generation module and a self-adaptive optimization module. Firstly, skin impedance, blood flow and temperature parameters are collected by the system, and a collaborative strategy is generated through multi-parameter analysis of an intelligent control module; the time-space cooperative control module synchronously adjusts the ion release and electromagnetic field excitation time sequence; the multi-channel ion release module realizes quantitative release of multiple types of ions by utilizing microfluidics; the multi-band electromagnetic generation module outputs low-frequency, medium-frequency and high-frequency programmable electromagnetic fields; the adaptive optimization module dynamically corrects treatment parameters based on the electrophysiological feedback. According to the system, multi-modal fusion of iontophoresis and electromagnetic stimulation is realized, and the accuracy and individualization level of treatment are improved.
Owner:归益堂中医健康科技(深圳)有限公司

Electromagnetic personalized treatment parameter generation method and system

The invention belongs to the technical field of electromagnetic stimulation treatment, and discloses an electromagnetic personalized treatment parameter generation method and system, and the method comprises the steps: obtaining a multi-source physiological signal of a patient in an electromagnetic stimulation treatment process, obtaining the personal information and medical history information of the patient, carrying out the preprocessing of the multi-source physiological signal, and carrying out the processing of the multi-source physiological signal; extracting time-domain features, frequency-domain features and nonlinear features, combining the time-domain features, the frequency-domain features and the nonlinear features with personal information and medical history information of the patient to form a physiological response feature vector, inputting the physiological response feature vector into a preset physiological response evaluation model, and calculating to obtain a current physiological state evaluation result of the patient. Inputting the current physiological state evaluation result and the current treatment stage information of the patient into a preset parameter adjustment model to generate an electromagnetic parameter adjustment scheme; through the treatment strategy chain selected based on the data information of the to-be-migrated data and the treatment demand information, data treatment is carried out while data migration is carried out on the to-be-migrated data, and the treatment efficiency during data migration is improved.
Owner:SANQIAOHUI (FOSHAN) NEW MATERIAL CO LTD

Galvanic and electromagnetic stimulator miniaturized by microfabrication

The invention relates to a stimulation module combining galvanic and electromagnetic stimulation, consisting of a housing having: • two electrodes positioned to come into contact with the mastoids of the user and connected to a source of electric current, one of the electrodes being active, the other of the electrodes being passive • at least one electromagnetic coil for generating electromagnetic stimulation without contact, formed on an electrically insulating substrate, the substrate being associated with a heat sink • two separate compartments for housing, on the one hand, the electrical stimulation circuit connected to the electrodes and, on the other hand, the electromagnetic stimulation circuit supplying the coil • an electronic control circuit for controlling the sequences of electrical and electromagnetic stimulation, including a Bluetooth module for receiving remote control signals of the stimulation parameters.
Owner:NEURAL BALANCE INNOVATION

Sensing and stimulation device

A sensing and stimulation device arranged on an ear of a subject is disclosed. The device includes a coil structure, a setting structure combined with the coil structure, and a control module coupled to the coil structure. The setting structure is configured to position the coil structure on the ear. The control module is configured to drive the coil structure for an eddy current induction measurement to an ear measurement area, and to drive the coil structure for an electromagnetic stimulation to an ear stimulation area. The control module controls at least one parameter of the electromagnetic stimulation based on at least one measurement result of the eddy current induction measurement.
Owner:NATIONAL TSING HUA UNIVERSITY

Electromagnetic stimulation rehabilitation physiotherapy equipment and use method thereof

The invention relates to the technical field of electromagnetic physical therapy equipment, and discloses electromagnetic stimulation rehabilitation physical therapy equipment, which comprises a fixing frame assembly and a rehabilitation physical therapy device, the fixing frame assembly is characterized in that symmetrical splicing bodies are connected through a middle hinge shaft, positioning bolt holes are formed in the bottoms of the symmetrical splicing bodies, position adjusting grooves with scale marks are formed in the front ends of the symmetrical splicing bodies, and adsorption magnets are arranged at the rear ends of the symmetrical splicing bodies; the detachable connecting mechanism comprises a cross-shaped positioning base which is embedded in the position adjusting groove in a sliding manner through a cross-shaped positioning mechanism; when the mechanical exercise structure provides resistance training, the phototherapy, electromagnetic pulse and mechanical vibration energy are synchronously released by the phototherapy and electromagnetic combined treatment cylinder, and in the movement process, the phototherapy, electromagnetic pulse and mechanical vibration energy form the immediate synergistic effect of movement, repair and activation at the limb contact end. Rehabilitation training is upgraded from pure muscle strength training to comprehensive intervention for promoting tissue regeneration, and the rehabilitation period is remarkably shortened.
Owner:重庆市渝北区人民医院 +1

Gradient tuning type exciting coil structure and system for biological electromagnetic stimulation

The invention discloses a gradient tuning type excitation coil structure and system for biological electromagnetic stimulation, and relates to the technical field of biological electromagnetic stimulation. The coil structure comprises a plurality of layers of 8-shaped stimulation coils which are horizontally placed above a biological electromagnetic stimulation target area, the inner diameter of each layer of 8-shaped stimulation coil is gradually increased layer by layer from bottom to top, and two coil units in each layer of 8-shaped stimulation coil are bilaterally symmetrical. The multi-layer 8-shaped stimulation coil is used for accessing excitation current through the discharge circuit so as to play a biological electromagnetic stimulation role on a target area, so that the focusing performance of the target area can be remarkably improved on the premise of not losing much induced electric field intensity through gradually increasing the inner diameters of the coils from bottom to top layer by layer, and the focusing performance of the target area is improved. Parts of hidden dangers caused by too large focusing area are eliminated, high electric field intensity is generated at the cerebral cortex, effectiveness of brain stimulation is guaranteed, and practical application and popularization are facilitated.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY

System and method for stimulating and activating stem cells using electromagnetic fields for the treatment of neurodegenerative diseases

The invention relates to a system and method for treating neurodegenerative diseases through the activation and stimulation of stem cells using electromagnetic fields. The activated stem cells are then delivered via nasal administration to cross the blood-brain barrier and migrate to the brain, where further electromagnetic stimulation enhances the cells' effectiveness in regenerating and repairing damaged areas of the central nervous system.
Owner:PERISO

Waterproof and oil-proof portable automatic heating laparoscopic enema and electromagnetic stimulator for preventing constipation

The invention relates to a constipation-preventing waterproof and oil-proof portable automatic-heating laparoscopic enema and electromagnetic stimulator, which comprises a grip and an expansion component mounted at the top, a mounting cavity is formed in the grip, a driving motor is arranged in the mounting cavity, a hollow shaft is connected to the tail end of an output shaft of the driving motor, and the hollow shaft is connected to the tail end of the output shaft of the driving motor. According to the dilatation device, the dilatation assembly is arranged, a driving motor of the dilatation assembly drives the hollow shaft to rotate, and the rotating disc connected with the tail end of the hollow shaft synchronously starts to rotate, so that the position of a strip-shaped sliding groove in the surface of the rotating disc is driven to change; then a limiting sliding block sliding on the surface of a strip-shaped sliding groove is driven to move outwards, so that a connecting support is pushed to synchronously move outwards, the connecting support slides on a connecting base, the connecting base and an expansion plate are pushed to start to rotate around a rotating center, the expansion plate is driven to start to rotate and expand, and the anus of a user is expanded through the expansion plate; medical staff can conveniently treat the anus of the patient.
Owner:高美惠

An overlapping stimulation coil assembly and system for bioelectromagnetic stimulation

The present invention discloses an overlapping stimulation coil assembly and system for bioelectromagnetic stimulation, which relates to the field of bioelectromagnetic stimulation technology. The assembly includes a lower stimulation coil and an upper stimulation coil for vertical placement above a bioelectromagnetic stimulation target area, wherein the upper and lower stimulation coils have the same and similar geometric structure of a semicircular coil structure, the upper and lower stimulation coils are arranged overlappingly, and the arc portion of the lower stimulation coil, the arc portion of the upper stimulation coil, the straight long axis portion of the lower stimulation coil, and the straight long axis portion of the upper stimulation coil are arranged in sequence from bottom to top, and the upper and lower stimulation coils are used to respectively access excitation currents through different discharge circuits to jointly exert bioelectromagnetic stimulation on the target area. In this way, while ensuring that the stimulation intensity reaches the stimulation threshold, the focusing of the stimulation coil is improved, the stimulation depth within the skull is enhanced, the adverse effects on non-target areas are effectively reduced, and the safety of transcranial electromagnetic stimulation treatment is ensured.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY

body of the stimulating coil

1. The name of the design product: the main body of stimulating coil. 2. The use of the design product: the product is used in the field of medical devices, and the overall use is to regulate the target of the subject during the electromagnetic stimulation of the subject. 3. The design points of the design product: in the solid line drawing part. 4. The picture or photo that best indicates the design points: perspective view 1. 5. Other circumstances that need to be explained: the dotted line part in the picture does not constitute a part of the appearance design claimed.
Owner:BEIJING GALAXY CIRCUMFERENCE TECH CO LTD

Electromagnetic stimulation equipment and multi-stage boosting device thereof

The invention discloses electromagnetic stimulation equipment and a multi-stage boosting device thereof, the multi-stage boosting device is formed by connecting a plurality of basic voltage multipliers, and a plurality of first current direction limiting elements, a plurality of second current direction limiting elements, a first energy storage element and a second energy storage element are used for storing energy to generate direct-current high-voltage electricity for electromagnetic stimulation. Furthermore, the first current direction limiting element and the first energy storage element are electrically connected in series with an external power supply, the first current direction limiting element is connected in parallel with a second current direction limiting element which is opposite to the current limiting direction of the first current direction limiting element, and the second current direction limiting element is connected in series with the second energy storage element; the first current direction limiting element and the second current direction limiting element are conducted or not conducted along with the polarity of the input voltage and are used for switching the current direction so that the external power supply can charge the first energy storage element and the second energy storage element in different periods respectively, the external power supply and the first energy storage element provide charging in the charging process of the second energy storage element, and the cross voltage is two times that of the first energy storage element. And the second energy storage elements are mutually connected in series for output application.
Owner:ADDON TECH LTD

Ultrasonic electromagnetic stimulation therapeutic instrument

1. The name of the design product: ultrasonic electromagnetic stimulation therapeutic instrument. 2. The use of the design product: for the auxiliary treatment of cardiovascular and cerebrovascular diseases, soft tissue contusion, and nervous system disease rehabilitation. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view 1.
Owner:GUANGDONG YINQUE MEDICAL TECH CO LTD

Peripheral stimulation parameter prediction method and system based on multi-modal feedback

The invention discloses a peripheral stimulation parameter prediction method and system based on multi-modal feedback. The method comprises the steps of obtaining corresponding multi-modal feedback data when electromagnetic stimulation is applied to a target muscle group; determining physiological response intensity corresponding to the target muscle group based on the multi-modal feedback data; based on a machine learning regression algorithm, establishing a treatment parameter prediction model corresponding to the target muscle group according to suitable stimulation parameters corresponding to the electromagnetic stimulation and the physiological response intensity; and when the target muscle group is treated, predicting ideal treatment parameters corresponding to the target muscle group according to the real-time physiological response intensity corresponding to the target muscle group and the treatment parameter prediction model. Therefore, accurate prediction of the muscle peripheral treatment parameters based on multi-modal feedback can be realized, and the pertinence and the treatment effect of muscle group peripheral electromagnetic treatment are improved.
Owner:NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV +1

Portable acupuncture and massage electromagnetic head therapeutic apparatus

The invention relates to the technical field of medical instruments, in particular to a portable acupuncture and massage electromagnetic head therapeutic apparatus, and aims to solve the problem that an existing portable acupuncture and massage electromagnetic head therapeutic apparatus cannot automatically adapt to patients with different head circumferences. The portable acupuncture and massage electromagnetic head therapeutic apparatus provided by the invention comprises a therapeutic head cover, and further comprises a self-adaptive wearing assembly which is arranged in the therapeutic head cover and performs self-adaptive adjustment according to the size of the head of a patient; the multiple groups of treatment assemblies are movably arranged in the treatment hood and are used for carrying out head electromagnetic treatment on the patient; according to the invention, the self-adaptive wearing assembly is arranged, so that the head therapeutic apparatus can automatically adapt to patients with different head circumferences, and the convenience and universality of therapeutic operation are improved; by arranging the four groups of treatment assemblies with adjustable positions, a user can quickly switch treatment areas through simple operation according to the specific uncomfortable position of the head, so that the operation convenience is improved, and electromagnetic stimulation can directly act on a focus.
Owner:SHIYAN CITY PEOPLES HOSPITAL (PEOPLES HOSPITAL AFFILIATED TO HUBEI UNIV OF MEDICINE)

Apparatus and method for fat and cellulite reduction using RF energy in combination with magnetic muscle thermostimulation (EMS)

A system for cosmetically treating a patient's skin or body with one or more EMS coils and / or RF electrodes mounted on a planar holder; a hydrogel containing gel pad, the gel pad being positionable between the holder and the skin tissue; wherein the gel pad being of a material that is biocompatible and conducts RF and / or EMS energy when EMS energy is applied from the one or more EMS coils; a programmable controller to activate the one or more EMS coils; the programmable controller, after the planar holder is applied to the skin tissue, being configured to activate one or more of the plurality of EMS coils to provide treatment in the form of stimulation to the skin tissue.
Owner:BIOS SRL

Cooling device for stimulation unit of electromagnetic stimulation apparatus

In a cooling device for a stimulation unit of an electromagnetic stimulation apparatus, the stimulation unit includes a coil assembly, the cooling device includes a casing having an accommodating space for accommodating the coil assembly and a flexible bag, the casing includes a front cover which is a disk structure, the coil assembly is fixed to a side of the front cover by an encapsulant, the periphery of the front cover is provided with multiple first fixed parts; a rear cover, which is a cover structure having a bottom and a circular lateral portion, an edge of the circular lateral portion is fixed with multiple second fixed parts opposite the first fixed parts; and the flexible bag is filled with a coolant. After the rear cover and the front cover are installed, the flexible bag provides a cooling effect to the coil assembly through convection or conduction.
Owner:ADDON TECH LTD

System and method for restoring color perception to the blind

A system and method are disclosed for causing or enhancing the perception of color in a blind or visually impaired person. The system may comprise: an electromagnetic stimulation device associated with the blind or visually impaired person; and a visualization device for receiving an image and detecting a color of an object in the image, wherein the electromagnetic stimulation device is configured to stimulate the blind or visually impaired person based on a parameter of electromagnetic stimulation that varies based on the color detected by the visualization device. The method may comprise: varying a parameter of electromagnetic stimulation of an electromagnetic stimulation device, associated with an eye of the blind or visually impaired person, based on which color is detected by a visualization device that is used in conjunction with the electromagnetic stimulation device; and stimulating the eye with the electromagnetic stimulation device according to the parameter of electromagnetic stimulation.
Owner:UNIV OF SOUTHERN CALIFORNIA

Wearable electromagnetic stimulation waistband for rehabilitation after neural intervention operation

The invention relates to the technical field of medical apparatus and instruments, and discloses a wearable electromagnetic stimulation waistband for rehabilitation after neural intervention, the wearable electromagnetic stimulation waistband for rehabilitation after neural intervention comprises a fixing band, and by arranging an adjusting mechanism and a connecting mechanism, when the tightness of the waistband needs to be adjusted, the adjusting mechanism can adjust the tightness of the waistband; a U-shaped rod is pulled upwards to drive a transverse plate to move upwards and compress a fixing spring, meanwhile, a clamping block at the bottom of the transverse plate is separated from a rectangular groove in a circular plate, locking on a rotating rod is relieved, then a rotary knob is rotated to drive the rotating rod to rotate, the rotating rod drives a winding drum to rotate, and therefore an adjusting belt wound around the outer side of the winding drum is folded and unfolded, and after the adjusting belt is adjusted to the proper tightness degree, the adjusting belt is fixed. The U-shaped rod is loosened, the clamping block is clamped into the rectangular groove in the circular plate again under the elastic action of the fixing spring, adjustment is completed, the purpose of conveniently adjusting the waistband according to the patient is achieved, the electromagnetic mechanism is detached by arranging a limiting frame, the electromagnetic mechanism and the fixing mechanism, and the purpose of conveniently detaching and cleaning is achieved.
Owner:榆林市中医医院

The main body of the stimulation coil

1. Name of this design product: Body of the stimulation coil. 2. Purpose of this design: This product is used in the field of medical devices, and its overall purpose is to regulate the target points of the subject during the process of receiving electromagnetic stimulation. 3. The key design features of this product are the solid line drawings. 4. The picture or photo that best illustrates the key design points: Design 1 3D diagram 1. 5. Design 1 is designated as the basic design. 6. Other situations requiring explanation: In the drawings of this design, the dashed lines indicate the parts that are not claimed.
Owner:BEIJING GALAXY CIRCUMFERENCE TECH CO LTD

Devices, systems and methods for treating back pain with EMS

Devices, systems, and methods for treating lower back pain (e.g., chronic lower back pain) with electromagnetic stimulation are disclosed. A device for treating lower back pain can have a seat portion, a backrest portion, and an electromagnetic stimulation coil operatively associated with the backrest portion. The electromagnetic stimulation coil can be positioned to apply electromagnetic stimulation to a spine of a patient while the patient is seated on the seat portion.
Owner:THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS

System and method to induce epigenetic changes to the cells and tissue of the eye and orbit

Methods, systems, and apparatus for causing changes to cells or tissue within or adjacent to an eye. The system includes an external RF coil configured to transmit RF signals. The system also includes a wearable device configured to be removably disposed on the eye, the wearable device including a plurality of internal radiofrequency (RF) coils configured to receive the RF signals from the external RF coil and a plurality of stimulating electrodes configured to electromagnetically stimulate a portion of the eye or an area adjacent to the eye, causing changes to cells or tissue within or adjacent to the eye.
Owner:UNIV OF SOUTHERN CALIFORNIA

Targeted nucleus and cortex paired transcranial electromagnetic combined stimulation system

PendingCN120204634AElectrotherapySensorsPaired stimuliElectro stimulation
The invention provides a targeted nucleus and cortex paired transcranial electromagnetic combined stimulation system, which comprises a deep layer-cortex paired combined regulation and control module used for obtaining a deep nucleus-cortex paired combined stimulation strategy; the individualized navigation engine module is used for carrying out transcranial electromagnetic stimulation individualized positioning on the deep nuclei and the cortex target spots based on a pairwise combined stimulation strategy and the individual imaging data of the deep nuclei and the cortex target spots to obtain target spot parameters; the deep electrical stimulation synchronous electroencephalogram acquisition module is used for acquiring a cortex evoked potential incubation period; the individualized sequential pairing stimulation technology module is used for obtaining transcranial electromagnetic stimulation time interval parameters; and the multi-device linkage software platform module is used for realizing time sequence synchronous regulation and control of the transcranial electromagnetic stimulation device and other devices and completing paired transcranial electromagnetic combined stimulation of the targeted nuclei and the cortex. According to the method, the time-space parameters are accurately controlled, so that the tTIS and the TMS can act synergistically.
Owner:BEIJING INST OF TECH

Electromagnetic stimulation apparatus and booster device thereof

An electromagnetic stimulation apparatus with a booster device using first and second current direction limiting elements and first and second energy storage elements to generate electromagnetic stimulation. The first current direction limiting element and the first energy storage element are electrically connected to an power supply in series, the first current direction limiting element is connected to the second current direction limiting element in parallel, and the second current direction limiting element is connected to the second energy storage element in series. The first and second current direction limiting elements are electrically connected or disconnected to switch the current direction and charge the first and second energy storage elements respectively at different periods. When charging the second energy storage element, the external power supply and the first energy storage element connected to the second energy storage element in series provide a cross-voltage doubling that of the first energy storage element.
Owner:ADDON TECH LTD

Device to electromagnetically stimulate new organic cell proliferation

An apparatus for proliferation of organic tissue by exposure to electromagnetic field is disclosed that comprises an electromagnetic patch 101 comprising one or a plurality of electromagnetic coils 103 each generating an electromagnetic field; and a battery powered drive unit 102 which supplies signals to the electromagnetic coils for applying a particular dosage of electromagnetic field to a target tissue region. The electromagnetic patch 101 is specifically customised to an individual subject user and to an individual body portion and tissue region of said individual user. The drive signal sequence is individually tailored to the electromagnetic patch for delivering a particular dosage programme of electromagnetic field for the particular subject user.
Owner:EMDA LTD

Ultrasonic electromagnetic stimulation therapeutic instrument

1. The name of the design product: ultrasonic electromagnetic stimulation therapeutic instrument. 2. The use of the design product: for the auxiliary treatment of cardiovascular and cerebrovascular diseases, soft tissue contusion, and nervous system disease rehabilitation. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view 1.
Owner:GUANGDONG YINQUE MEDICAL TECH CO LTD

Pulsed electromagnetic fields to treat neurotrophic keratitis

A system for applying electromagnetic stimulation to a periocular region of an eye to treat neurotrophic keratitis, includes: an electromagnetic field generator producing a time-varying magnetic field with a pulse duration of about 200 microseconds to about 400 microseconds, a rate of change of about 10,000 Tesla per second to about 20,000 Tesla per second, and a pulse rate of about 1 Hz to about 50 Hz; and a positioner configured to align the output of the electromagnetic field generator with the cornea, enabling treatment that enhances nerve regeneration and epithelial integrity.
Owner:EPITECH MEDICAL INC

Low-intensity pulse electromagnetic stimulation system and method for accelerating human lumbar vertebra recovery

The invention discloses a low-intensity pulse electromagnetic stimulation system and method for accelerating human lumbar vertebra recovery, and belongs to the technical field of biomedical engineering. A monitoring module is designed to collect lumbar vertebra multi-segment bioelectrical impedance data, an impedance distribution map is constructed through a control module, differentiated stimulation parameters are distributed, impedance deviation is calculated through a feedback adjustment module comprising an independent hardware processing unit, a correction instruction is generated, and finally independent pulse output is adjusted through an execution module. The method has the advantages that by integrating multi-source impedance data to construct the atlas and introducing pure hardware feedback, the pain points of blind attenuation of dosage and high software closed-loop delay of traditional equipment are thoroughly solved, multi-segment space targeted regulation and control and sub-millisecond dosage locking of the lumbar vertebra are realized, and intelligent support is provided for lumbar vertebra rehabilitation.
Owner:ZHENGZHOU RAILWAY VOCATIONAL & TECH COLLEGE

Comprehensive equipment for perfusion and dispersion treatment of benign breast diseases

ActiveCN224193940Uplay a dredging roleachieve therapeutic effectElectrotherapyPressure infusionMammary ductLactiferous duct
The utility model discloses a comprehensive device for perfusion and dispersion treatment of benign breast diseases, which comprises an electromagnetic pulse treatment device body, an infrared light breast cup, a thermal therapy breast cup, a breast perfusion device and an injection pump, and the released electromagnetic pulse is transmitted to the mammary gland through an electromagnetic pulse transmission device mounted on the electromagnetic pulse output end, so that the mammary gland is electromagnetically stimulated. According to the utility model, after the medicine is injected into the mammary gland through the injection equipment, the acupoints in the breast are stimulated to expand the catheter in the mammary gland through the effects of infrared light and electromagnetic pulse and the acupoints under the mammary gland of the human body and the theory of traditional Chinese medicine, so that the effect of dredging the mammary gland is achieved; therefore, the perfused medicine can be quickly dispersed into the whole breast, the effect of treating a lesion part in the breast by the medicine is achieved, and the treatment effect of a lesion body of the perfused medicine is better.
Owner:XUZHOU GUANGKE NEW-TECH DEV CO LTD

Double-network semi-cross chain stacking bionic cartilage magnetoelectric gel, preparation method and application thereof

The application relates to the field of biomedical engineering and specifically relates to a double-network semi-crossed chain stacking biomimetic cartilage magnetoelectric gel, a preparation method and application thereof. The biomimetic cartilage magnetoelectric gel is prepared by adding 0.5-2 parts of superparamagnetic ferroferric oxide nanoparticles, 2-8 parts of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and 2-8 parts of sodium alginate into 100 parts of a solvent, wherein the solvent is prepared according to a proportion of water:N,N-dimethylformamide:dichloromethane=4-6:1-2:2-4. The biomimetic cartilage magnetoelectric gel has good biocompatibility and a functional environment of biomimetic cartilage, can release electromagnetic stimulation to promote cell proliferation and migration, promote chondrocyte induced differentiation, provide mechanical bearing and support for the repair of damaged cartilage, promote the generated new cartilage tissue to have transparent cartilage characteristics similar to normal cartilage tissue, is superior to an AFe group induced by simple magnetic stimulation and a VA group induced by simple piezoelectric stimulation, and has a wide application prospect.
Owner:LANZHOU UNIV