89 results about "Electromagnetic stimulation" patented technology

Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and / or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and / or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and / or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and / or electrophereis can also be used with the disrupting agents.

An electromagnetic stimulation device which is comprised of a plurality of overlapping coils which are able to be independently energized in a predetermined sequence such that each coil will generate its own independent electromagnetic field and significantly increase the adjacent field. The coils are co-planar and are disposed in an ergonomic body wrap, which is properly marked to permit an unskilled patient to locate the body wrap, on a particular part of the body, of the patient so that the stimulation coils will maximize the electromagnetic stimulation on the selected nerves, muscles, and / or body tissues near the treated area. The device can be used to treat medical conditions including: muscular atrophy, neuropathic bladder and bowel, musculoskeletal pain, arthritis, as well as possible future applications in the prevention of deep vein thrombosis and weight reduction.

An electromagnet coil comprising Litz wire windings and power leads without break or interruption is cooled by a perfluorinated liquid by sensible and phase change heat transfer in a closed system. The electromagnet coil may be housed in a pentagonal or hexagonal pressure vessel to allow high packing densities in an array or helmet configuration. The helmet is then lowered over a human cranium for transcranial electromagnetic stimulation. The Litz wire windings reduce the power and voltages required for operation, yet allow production of over 2 T of accurately directed magnetic pulses for direct nerve or neuron stimulation. The perfluorinated liquid maintains the temperature of the helmet to less than 35-40° C., ensuring a comfortable temperature device for a human test subject. A utility cable connects the helmet to an external cooling unit and an external power supply.

A device for, and method of restoring kidney function, the method including the steps of: (a) providing a device including: (i) a conducting coil, and (ii) a signal generator, operatively connected to a power supply, for providing a plurality of electrical impulses to the coil; (b) disposing the conducting coil proximate to a kidney of a patient, and (c) delivering the electrical impulses conducting to the conducting coil, so as to produce an electromagnetic field, the electromagnetic field acting so as to stimulate the kidney and at least partially restore kidney function.

Current treatment options for Overactive Bladder and Urinary Incontinence include exercise and behavioral modifications, pharmacological therapies, surgical intervention, and neuromodulation. Although each of these treatments is used in the treatment of individuals with these conditions, each has severe limitations. Building on the limitations of existing therapies, and with the distillation of lessons learned from the field of pulsed electric stimulation, the present invention employs Low Frequency Induction Therapy for the delivery of an effective, cost efficient, noninvasive alternative to available treatment options. The device of the present application allows for consistent, user-friendly modulation of the pudendal nerve and the sacral plexus, via pulsed electromagnetic stimulation of the posterior tibial nerve, on an outpatient basis. The device has two primary components: a programmable Logic Controller (LC), which generates the required current, and a Conductive Wrap (CW), through which the current is channeled in generating the pulsed electromagnetic fields.

Current treatment options for Overactive Bladder and Urinary Incontinence include exercise and behavioral modifications, pharmacological therapies, surgical intervention, and neuromodulation. Although each of these treatments is used in the treatment of individuals with these conditions, each has severe limitations. Building on the limitations of existing therapies, and with the distillation of lessons learned from the field of pulsed electric stimulation, the present invention employs Low Frequency Induction Therapy for the delivery of an effective, cost efficient, noninvasive alternative to available treatment options. The device of the present application allows for consistent, user-friendly modulation of the pudendal nerve and the sacral plexus, via pulsed electromagnetic stimulation of the posterior tibial nerve, on an outpatient basis. The device has two primary components: a programmable Logic Controller (LC), which generates the required current, and a Conductive Wrap (CW), through which the current is channeled in generating the pulsed electromagnetic fields.

A body orifice remodeling device includes a cylindrical handpiece having a defined length which is adapted to be inserted into the body orifice and an elongated monopolar electrode mounted outside on the circumference of the cylindrical handpiece and extending substantially along the length of the handpiece. A source of radio frequency (RF) energy in the handpiece is configured to generate RF energy to the elongated monopolar electrode; and a source of electromagnetic stimulation energy (EMagS) in the handpiece is configured to generate (EMagS) energy.

A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.

The electromagnetic stimulation device contains at least a positive electrode and at least a negative electrode. An insulating gap having width of a first distance is maintained between the positive and negative electrodes. The positive and negative electrodes are at least at a second distance away from a nerve to be stimulated. A preset voltage is applied to the positive and negative electrodes so that a low-power, low-temperature, high-frequency electromagnetic field covering and stimulating the nerve is produced between the positive and negative electrodes. By the stimulation of the low-power, low-temperature, high-frequency electromagnetic field, the nerve's threshold is increased, the nerve's transmission capability is reduced, and therefore the nerve pain is effectively eased.

The invention provides a finished automobile electromagnetic stimulation reverse modeling method. The method includes the following steps that views in various directions are obtained according to shot pictures of an automobile body, modeling software is imported, a curved surface partitioning technology is utilized to divide the finished automobile body into curved surface blocks with continuous curvatures , and all the curved surface blocks are spliced and sewn to form a finished automobile model; the finished automobile model is simplified; mesh generation is conducted on the simplified model; the generated finished automobile mesh model is imported into the electromagnetic stimulation software for conducting stimulation analysis on finished automobile electromagnetic performance. According to the finished automobile electromagnetic stimulation reverse modeling method, the finished automobile electromagnetic stimulation model is established under the condition that a sample automobile is possessed, so that automobile electromagnetic performance stimulation analysis operation does not need to depend on finished automobile original automobile data any longer; when the finished automobile original automobile data are not available, expensive three-coordinate scanning does not need to be conducted on the sample automobile, the pictures obtained by simple and feasible shooting are used as data sources for conducting reverse modeling, on the premise that accuracy of the model is guaranteed, cost of finished automobile reverse modeling is greatly reduced, the modeling workload is effectively reduced, and time needed for modeling is effectively shortened.

Methods, devices and systems for Transcranial Magnetic Stimulation (TMS) are provided for synchronous, asynchronous, or independent triggering the firing multiple of electromagnets from either a single power source or multiple energy sources. These methods are particularly useful for stimulation of deep (e.g., sub-cortical) brain regions, or for stimulation of multiple brain regions, since controlled magnetic pulses reaching the deep target location may combine to form a patterned pulse train that activates the desired volume of target tissue. Furthermore, the methods, devices and systems described herein may be used to control the rate of firing of action potentials in one or more brain regions, such as slow or fast rate rTMS. For example, described herein are multiple electromagnetic stimulation sources, each of which are activated independently to create a cumulative effect at the intersections of the electromagnetic stimulation trajectories, typically by means of a computerized calculation.

The invention relates to a preparation method of the intelligent self-lubricating composite material containing the electromagnetic trigger microcapsules. The intelligent self-lubricating composite material comprises a conductive polymer matrix and the electromagnetic trigger microcapsules. According to the invention, the release of core-material active substances by the microcapsules are remotelyregulated and controlled through external electromagnetic stimulation, and self-repairing of lubrication and corrosion resistance of the conductive polymer composite material is realized. Compared with existing self-lubricating composite materials, the composite material provided by the invention has continuously variable electric current and magnetic field intensity which are triggered by electromagnetic stimulation, so that tunable stimulation response is realized. The intelligent composite material system and a self-repairing / self lubricating strategy thereof provided by the invention havelarge application potential and market value in the fields of self-lubricating bearings, anti-corrosion coatings, battery electrode materials and the like.

The invention relates to a probe for deep brain electromagnetic coupling stimulation and electric signal detection, and belongs to the technical field of infrared / terahertz. The probe comprises a probe tubular structure and a probe end seal. The probe tubular structure is sequentially composed of a probe shell, a polycarbonate insulating sleeve layer, a brass sleeve layer, a polycarbonate base layer, a silver film and a silver iodide film from the outer side to the inner side. The brass sleeve layer extends out of the probe tubular structure to form a probe tip; an optical fiber lens is embedded in the probe tip; and the tip of the probe tip is sealed with cycloolefin resin. The probe provided by the invention not only can couple a high-frequency electromagnetic signal into a specific target in the brain of a higher animal, but also can cling to nerve cells of the target to carry out real-time electric signal detection on the stimulation effect. The deep brain electromagnetic stimulation probe can provide an efficient, minimally invasive and high-targeting stimulation mode and can accurately detect the action potential of a functional area to finally achieve more effective deep brain electromagnetic stimulation and detection.

A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.