15 results about "Skeletal tissues" patented technology

The invention relates to the technical field of medical informatics, in particular to a construction method of an osteoporotic fracture risk prediction model. The method comprises the following steps: acquiring an included angle between a foot and the ground, a step speed and a CT image of a target person in a monitoring process; dividing pixel points in the CT image into a plurality of bone tissue areas; according to the shape distribution characteristics of the edge lines in the bone tissue area, bone characteristic values of the bone structure are obtained; obtaining a posture control factor of each gait according to the included angles between the left and right feet of the target person in each gait and the ground; determining an abnormal posture index of each gait in combination with the posture control factor and the corresponding step speed; obtaining a control disorder coefficient of each time period according to the numerical distribution characteristics and the change characteristics of all the posture control factors in each time period; and determining an osteoporosis evaluation value by integrating the bone characteristic value and the disorder control coefficient of the skeleton structure. The accuracy of the bone comprehensive evaluation result of the target person is improved.

The invention discloses a skeleton tissue subdivision and reconstruction method based on an SAM series model. The method comprises the following steps: converting image data into a format supported by the model; generating an optimized feature map in the convolutional network; performing feature slicing operation on the feature map, calibrating slices and reconstructing the slices into a complete feature map; inputting the feature map into a detection head to generate a candidate box and a confidence score, embedding prompt information into a segmentation decoder, and fusing the prompt information with the feature map to generate a segmentation mask; storing the feature result of the current frame in a memory bank; the prompt information is coded into an embedded mode, and after the prompt information is fused with the feature map, segmentation masks related to the prompt are generated; and formatting the target detection result, adjusting the size of the segmentation mask to be aligned with the input image, and storing the detection and segmentation result as a specified format file. According to the method, the bone tissue can be efficiently segmented, and boundaries can be accurately distinguished under the condition that the upper and lower bones are similar in shape and close in position.

A method for ultrasound stimulation of musculo-skeletal tissue structures includes generating a plurality of acoustic spatial-temporal modes comprised of a sinusoidal-complex, wherein the sinusoidal-complex has a modulation envelope that enhances spatial-temporal measurement accuracy at a site of a multi-layered biological tissue structure, and a pulse repetition frequency and duty cycle that are osteogenic at the site of the multi-layered biological tissue structure, beam steering the acoustic spatial-temporal modes to the site of the multi-layered biological tissue structure to promote tissue healing, and producing bi-modal stress levels in the multi-layered biological tissue structure that are sufficient to generate bone fracture healing.

The invention belongs to the technical field of passive filling materials for medical instruments, and discloses hydroxyapatite core-spun microspheres for injection filling and a preparation method of the hydroxyapatite core-spun microspheres. The hydroxyapatite core-spun microsphere is composed of inner-layer hydroxyapatite and an outer-layer coating material, the brittleness and roundness of the surface of the hydroxyapatite microsphere can be improved, the inflammatory reaction and granuloma occurrence rate of an injection site can be reduced, more importantly, the risk that the hydroxyapatite microsphere is gathered and fused with surrounding skeleton tissue can be improved, and safety is improved.

A suture transfer device and method of use provides the suture transfer device to facilitate passage of suture through a channel bored through a bone. The suture transfer device may also be installed upon a surgical drill. The device extends through bone tissue providing a temporarily installed suture passage with an overall cylindrical configuration and a linear trough, the device can be included on a bone drill during the drilling process, with the device deployed within the drilled channel within the bone upon completion of the drilled channel in the bone, providing smooth passage of one or more sutures during tissue repair through the linear trough, the device further 10 removed upon completion of the surgery without disruption of the suture or sutures. Kits are also provided.

A first waveform comprising a force response of a skeletal tissue undergoing a tetanic contraction during a first time period is obtained. One or more transformed waveforms are generated from the first waveform. The one or more transformed waveforms include at least one transformed waveform which encodes a rate of change of the first waveform over the first time period. Change points are identified within the one or more transformed waveforms. The change points occur at a plurality of time points within the first time period. A kinetic contractility vector is generated from the first waveform based on a comparison of values of the first waveform determined at the plurality of time points. The kinetic contractility vector characterizes the kinetic response of the skeletal tissue over the first time period. An effect is determined based on the kinetic contractility vector.

The present invention relates to an implantable device configured to deliver, to an injured bone site, components for revascularisation and bone repair, the device comprising: a first osteoconductive scaffold component adapted to hold and deliver to the injured bone site, growth factors for inducing cellular events that initiate healing; and comprising a second osteoconductive scaffold component adapted to hold and deliver to the injured bone site, viable autologous osteogenic and / or angiogenic cells, and wherein the device also comprises a third scaffold component adapted to promote bone cell proliferation and vascularity, whereby the scaffold components provide a stable mechanical environment for promoting bone cell proliferation and vascularity. The present invention also relates to a method of manufacture of the implantable device.

The invention provides a bone slice three-dimensional positioning adaptive adjustment method and device in combination with big data, and relates to the technical field of positioning adjustment, and the method comprises the steps: building a bone tissue three-dimensional model of a surgical site; calling historical operation case data to perform feature extraction and training, and constructing a bone slice positioning prediction model; inputting the bone tissue three-dimensional model into a bone slice positioning prediction model, and screening out an optimal position and an optimal angle; determining a bone sheet lifting shape design scheme; manufacturing a bone sheet lifting entity according to the bone sheet lifting shape design scheme, and performing implantation simulation in the virtual environment to obtain a bone sheet simulation implantation result; and the space interference state of the bone slice lifting entity is collected in real time and is dynamically adjusted. The technical problem that accurate matching of the bone structure of the patient is further affected due to the fact that changes of the bone form and damage characteristics cannot be effectively handled in the prior art can be solved, and the technical effect of improving the matching accuracy of the bone sheet and the bone structure is achieved.

The present invention relates to nanoparticles capable of crossing biological barriers. In particular, it refers to lipid nanoparticles configured to cross the blood-brain barrier, target skeletal tissues and effectively penetrate the skin barrier. The invention also encompasses compositions and applications thereof.

The invention relates to a joint prosthesis and a preparation method thereof, the joint prosthesis comprises a 3D printing joint prosthesis, the 3D printing joint prosthesis comprises a prosthesis joint and a prosthesis handle connected with the prosthesis joint, and the surface of the prosthesis joint is sprayed with polyether-ether-ketone. After the surface of the 3D printed joint prosthesis reaches the preheating temperature, polyether-ether-ketone powder is sprayed to the surface of the prosthesis joint through flame spraying, a firm, hard and compact polyether-ether-ketone coating with a crystal structure is formed on the surface of the prosthesis joint, mutual contact of the bone joint surfaces is facilitated, and the joint surface of the joint is protected; and meanwhile, the biocompatibility of the medical metal can be utilized for the non-sprayed part. In the actual use process, the contact surface is the contact between the polyether-ether-ketone and the cartilage, the friction factor is reduced to about 0.235, and the smoothness of the contact surface is greatly improved. And meanwhile, the polyether-ether-ketone has a water lubrication characteristic, is beneficial to the flow of interstitial fluid on the surface, has better lubricity than a medical metal surface, and is more beneficial to the surface contact between the implant and an original bone tissue.

The invention discloses a reconstruction method and device for an orthopedic case image. The method comprises the following steps: determining that a skeleton of the orthopedic case image meets a reconstruction requirement according to diagnosis requirement information; according to the diagnosis demand information, calling an edge detection algorithm to identify a bone tissue contour and a focus tissue contour of the orthopedic case image, and intercepting the image to obtain a tissue contour image; determining focus feature severity based on tissue feature parameters of bone tissues in the tissue contour image, and rendering the tissue contour image according to the focus feature severity to obtain a tissue rendering image; and obtaining a gray value parameter according to the tissue rendering image, and carrying out pixel enhancement processing on the tissue of the tissue rendering image to obtain an orthopedic reconstructed image. The lesion feature severity is determined based on the tissue feature parameters of the image, and the image is reconstructed according to the lesion feature severity, so that a doctor can intuitively determine the lesion condition of the patient according to the image color and brightness, and the diagnosis efficiency of the doctor is improved.

This invention discloses a method and apparatus for reconstructing orthopedic case images. The method, after determining that the skeleton in the orthopedic case image meets the reconstruction requirements based on diagnostic needs information, uses an edge detection algorithm to identify the contours of the skeletal tissue and lesion tissue in the orthopedic case image and extracts the image to obtain a tissue contour image. Based on the tissue feature parameters of the skeletal tissue within the tissue contour image, the severity of the lesion features is determined, and the tissue contour image is rendered according to the severity of the lesion features to obtain a tissue rendering image. Finally, grayscale parameters are obtained from the tissue rendering image, and pixel enhancement processing is performed on the tissue in the tissue rendering image to obtain the orthopedic reconstructed image. This invention determines the severity of lesion features based on the tissue feature parameters of the image and reconstructs the image according to the severity of the lesion features, allowing doctors to intuitively determine the patient's lesion condition based on image color and brightness, thereby improving the doctor's diagnostic efficiency.

The invention relates to an orthodontic anchor screw (100) for extra-alveolar skeletal anchorage comprising a threaded shank (10) configured to be screwed into a bone tissue and a head (20), which, in use, protrudes from the bone tissue and comprises an engagement portion (24) for orthodontic traction and / or thrust elements. A through opening (25) is formed in said engagement portion (24) for orthodontic traction and / or thrust elements, wherein said through opening (25) extends substantially along a direction (Y) orthogonal to a longitudinal axis (X) of the anchor screw (100) and comprises a section (25B) having a polygonal cross section, for stably receiving an orthodontic sector.

The present invention relates to the technical field of medical informatics, and specifically relates to a method for constructing an osteoporosis fracture risk prediction model. The method includes: obtaining the angle between the foot and the ground, the walking speed, and the CT image during the monitoring of the target person; dividing the pixel points in the CT image into multiple bone tissue regions; obtaining the bone mass characteristic values of the bone structure according to the shape distribution characteristics of the edge lines in the bone tissue regions; obtaining the posture control factor of each gait according to the angle between the left and right feet of the target person and the ground in each gait; combining the posture control factor and the corresponding walking speed to determine the posture abnormality index of each gait; obtaining the control disorder coefficient of each time period according to the numerical distribution characteristics and change characteristics of all the posture control factors within each time period; and determining the osteoporosis evaluation value by comprehensively considering the bone mass characteristic values of the bone structure and the control disorder coefficient. The present invention improves the accuracy of the comprehensive bone mass evaluation result of the target person.