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This invention relates to the field of eccentricity measurement technology, specifically to a puncture needle axis alignment eccentricity measuring device with a handle. It solves the problems of eccentricity measurement relying heavily on manual visual inspection with specialized instruments, resulting in low detection efficiency. Furthermore, the instruments are difficult to adapt to different models and sizes of puncture needles, requiring frequent fixture changes, and the measurement benchmark is difficult to establish accurately, leading to measurement errors. The device includes a base assembly with a rotating component at its top, and a linkage component at the top of each rotating component. A lifting detection mechanism is located inside the linkage component, and a benchmark positioning mechanism is located at the top of the inner side of the lifting detection mechanism. The invention utilizes the output end of a hydraulic cylinder to push up a movable ring, which in turn drives an adjusting rod to rise. This adjusting rod then synchronously raises the benchmark platform, allowing the device to accommodate puncture needles of different lengths.