The invention discloses a wolfberry drip irrigation cultivation method achieving double-layer cross straw covering, and belongs to the technical field of water saving drip irrigation cultivation in arid and semi-arid regions. According to the water saving drip irrigation method, aiming at soil and climate characteristics in the arid and semi-arid regions, by adopting the measures of wolfberry cutting seedling treatment, efficient furrow rainwater collection, drip irrigation cultivation in a furrow, drip irrigation system optimization and double-layer cross covering of crushed wheat straw and corn straw, the rainfall and irrigation water utilization rate is increased, and invalid waste of the water resource is reduced. Compared with a traditional wolfberry flood irrigation cultivation method, the total output is increased by 15.13%, the super fruit rate is increased by 13.6%, a C-class fruit rate is lowered by 4.6%, and the dry fruit average hundred-grain weight is increased by 14.44%;the protein content is increased by 2.53%, the polysaccharide content is increased by 10.42%, and the carotenoid content is increased by 45.169 mg / 100 g.