1results about How to "Overcome misjudgment" patented technology

The invention relates to the technical field of biological medicine, and discloses a multi-modal data analysis method for drug screening safety evaluation. By setting experiment duration and sampling intervals, multi-modal data such as genes and metabolites are collected from a drug treatment group and a control group at multiple time points, dimension standardization is performed on the two groups of data based on statistical characteristics of the control group, a comprehensive state vector is constructed, state changes of adjacent time points are utilized to form a discrete time differential component and a state evolution function, and a state evolution function is established. The method comprises the following steps: generating two groups of theoretical trajectories through initial state iteration, comparing the theoretical trajectories with actual observation at each time point to evaluate a multi-dimensional error, performing double accumulation in time and state dimensions to obtain a toxicity index of a drug treatment group and a baseline toxicity index of a control group, and calculating a dimensionless safety score for drug grading according to the relationship between the toxicity index and the baseline toxicity index. Therefore, the limitation of dependence on a single index or a single time point is overcome, and the multi-modal data fusion and full-cycle toxicity quantification capabilities are improved.