18results about How to "Precision editing" patented technology

The invention discloses a forward security encrypted data controllable editing method in a cloud environment, and belongs to the field of cloud computing. The method specifically comprises the steps that firstly, a cloud simulation environment is built and initialized; the trusted authorization mechanism calculates an encryption key # imgabs0 # of a data owner and a secret key # imgabs1 # or # imgabs2 # of a user or an editor, then the owner operates an Encrypt algorithm to encrypt given plaintext data msg, an original ciphertext ct is obtained and uploaded to a cloud server, and the user accesses through an edge node or the cloud server. The editor obtains the original ciphertext ct from the edge node or the cloud server, then carries out controllable purification on the original ciphertext ct to obtain a purified ciphertext ct ', and uploads the purified ciphertext ct' to the cloud server for user access; when a certain ciphertext is not purified any more, puncture is executed locally according to the message of the ciphertext, a purified key # imgabs3 # is obtained, and finally, when malicious purification occurs, the trusted authorization mechanism executes a tracking algorithm to obtain the owner identity of the original ciphertext ct or the editor identity of the purified ciphertext ct '. According to the method, the safe and controllable data editing and sharing requirements in the cloud environment are met.

The invention relates to the technical field of three-dimensional reconstruction, and provides a data synthesis method and a training method for monocular three-dimensional reconstruction based on synthesized data, and the method comprises the steps: 1, rendering a picture containing a specific object into a plurality of pictures I corresponding to the object at different angles; step 2, obtaining a mask m of the object based on the picture I, and 3, guiding the picture generation model to generate a new picture which conforms to the text description and retains the structural information of the specific object by utilizing the picture I by utilizing the mask m and the additionally input text description. According to the method, a large number of 3D models and picture pairs are generated through different viewpoints, styles and background conditions, a rich training data set is provided, and the generalization ability of the monocular three-dimensional reconstruction model can be remarkably improved through the diversity. By randomly applying disturbance within a certain angle range of a plurality of viewpoints (R, T), the adaptive capacity of the model to different camera poses is improved, and the robustness of monocular three-dimensional reconstruction is enhanced.

The invention relates to the technical field of grass carp (Ctenopharyngodon idella), in particular to a method for knocking out a grass carp SMYD3 gene and application of the grass carp SMYD3 gene. The nucleotide sequence of the gRNA is as shown in SEQ ID NO: 1. The method comprises the following steps: synthesizing gRNA of a target gene through in-vitro transcription, then mixing the gRNA with Cas9 protein, introducing the mixture into an animal pole in a grass carp fertilized egg single-cell period by adopting a microinjection mode, and hatching to obtain the grass carp F0 generation with the target gene mutation. According to the application, the knockout of the grass carp gene is efficiently realized, and an effective technical means is provided for developing grass carp breeding and gene function research.

The invention provides an image editing method and device based on text guidance, equipment and a medium. The method comprises the following steps: inputting an input picture, a source cue word and a target cue word into a model; an input picture is subjected to noise addition through an inversion process to form a noise picture, then the noise picture enters a reconstruction branch and an editing branch, and a cross attention graph of the reconstruction process of the reconstruction branch is injected into the editing branch to maintain the structure and content of the picture; a contrast attention focusing strategy is adopted in the inversion process, and attention is adaptively and accurately guided to an editing area according to attention leakage conditions of different degrees; then, a mask-guided hybrid sampling technology is used in an editing branch to provide different conditional guidance for an editing area and a non-editing area so as to ensure that change and retention in the image are balanced and integrated, only the area needing to be edited is modified in the editing process, unnecessary editing of the non-editing area is prevented, and the editing efficiency is improved. And the phenomenon of excessive editing is prevented.

The invention discloses a parking space editing method, device and equipment based on data synthesis and a medium, and the method comprises the steps: obtaining a parking space image and a label file thereof, and carrying out the semantic segmentation of the parking space image through a semantic segmentation model, and obtaining a parking space line mask; eliminating a parking space line in the parking space image based on the parking space line mask to obtain a target parking space image; modifying the line type or color of the parking space line mask to obtain a target parking space line mask; and performing data fusion on the target parking space line mask and the target parking space image to obtain a new parking space image, and modifying the tag file according to the attribute of the parking space line in the target parking space line mask. According to the method, the accurate parking space line contour can be obtained through the semantic segmentation technology, the parking space lines can be edited accurately, then the parking space lines are edited according to requirements to obtain different types of parking space lines, and the label of the original parking space image can be reused, so that the labeling cost and time for editing and generating new data are greatly reduced.

The embodiment of the invention is suitable for the technical field of images, and provides a face editing method and device, electronic equipment and a storage medium, and the method comprises the steps: extracting a first semantic mask and a second semantic mask in a to-be-edited face image; the first semantic mask comprises sub-masks corresponding to multiple semantic attributes respectively; the second semantic mask does not comprise a target sub-mask corresponding to the target semantic attribute needing to be edited; inputting the first semantic mask, the second semantic mask and an editing requirement corresponding to the target semantic attribute into a mask generation model for redrawing to obtain a third semantic mask; the mask generation model is used for reserving information corresponding to non-target semantic attributes in a third semantic mask based on the second semantic mask; and performing face editing on the to-be-edited face image based on the third semantic mask and an editing requirement to obtain an edited face image. By adopting the method, the refinement degree and controllability of face editing can be improved.

The invention relates to a PDMS-based valve assembly rapid creating and editing system establishing method, which comprises the following steps of: designing a grade library presetting unit, and narrowing a grade library selection range of a hand valve grade, an instrument valve grade and an accessory grade through a grade library presetting mode; the fitting principle establishing unit is used for setting a valve group fitting matching mode; establishing a valve selection unit for selecting a target valve type; the valve group positioning unit is used for editing the direction of a valve group, realizing automatic matching creation of valves and components thereof, predefining an element grade range and pre-screening valve types; automatically judging an end face connection form; all elements are accurately combined; and the direction of the valve group is accurately edited. The method and the device are used for realizing rapid creation and accurate positioning of valves and accessories thereof in process engineering pipeline modeling.

The application provides a three-dimensional face editing and system based on neural radiance field decoupling, which performs geometric editing on a three-dimensional face through a semantic mask according to random noise, performs three-dimensional consistent style migration on a material in a case where a reference image is given, and finally outputs a three-dimensional face that can be locally geometrically edited and overall style edited, so as to solve the problems of low generation quality, difficult training, difficult geometric control, difficult material decoupling control and ineffective style migration of the prior art.

The present application relates to the field of genetic engineering, in particular to a pig cell model of NF2 gene mutation and a construction method and application thereof. The construction method comprises the following steps: 1) designing and synthesizing pegRNA and Nick sgRNA according to the pig NF2 gene; 2) constructing a vector: taking an sgRNA expression plasmid as a skeleton, inserting pegRNA into a BbsI enzyme cutting site of the plasmid to construct a pCL108PE1 vector; taking the sgRNA expression plasmid as the skeleton, inserting Nick sgRNA into the BbsI enzyme cutting site of the plasmid to construct a pCL108NICK1 vector; 3) electrotransferring cells: simultaneously electrotransferring PE protease plasmid, the pCL108PE1 vector and the pCL108NICK1 vector into pig cells; 4) obtaining the pig cell model of NF2 gene mutation: culturing the electrotransferred pig cells, screening out positive clone cells and obtaining the pig cell model of NF2 gene mutation.

This application presents a gRNA probe library, its preparation and design methods, a method for targeting genes, and a nucleic acid imaging method. This application combines gRNA probes containing modified groups with nucleases, enabling dynamic observation of DNA and RNA by binding to target genomic sequences or RNA transcripts in living cells. By utilizing fluorescently labeled crRNAs, tracrRNAs, and sgRNAs, this application achieves real-time imaging of repetitive and non-repetitive sites, establishing a powerful gene imaging toolkit. Furthermore, the gRNA probe library prepared in this application will be applied to CRISPR systems for gene editing, transcriptional regulation, gene targeting, and delivery.

The invention relates to the technical field of dental medicine, in particular to a tooth model abrasion degree editing method and device, equipment and a storage medium. The method comprises the following steps: acquiring a tooth model; the tooth model is initialized, target data of the tooth model are determined, and the target data comprise an initial abrasion degree characteristic value of the tooth model; determining a target abrasion degree characteristic value input by a user; constructing a deformation parameter according to the target data and the target abrasion degree characteristic value; and according to the deformation parameters, performing deformation processing on the tooth model through a grid-based Laplace deformation method. According to the method, deformation parameters of Laplacian transformation are constructed by calculating an initial abrasion degree characteristic value of a tooth model and combining a target abrasion degree characteristic value input by a user in real time, that is, the tooth model conforming to the target abrasion degree characteristic value is generated in a grid-based Laplacian transformation mode; accurate and fast editing of the abrasion degree characteristics of the tooth model is realized.

The invention belongs to the technical field of preparation of nano composite materials, and particularly relates to a tungsten-doped Prussian blue nano composite material, a preparation method and application. The tungsten-doped Prussian blue nano composite material prepared by a one-pot hydrothermal method by taking polyvinylpyrrolidone as a reducing agent and a stabilizer and tungsten hexachloride, citric acid and potassium ferricyanide as reactants has excellent ROS (reactive oxygen species) removal capability and can protect intestinal epithelial cells and treat IBD (infectious bursal disease), and hydrogel is further taken as a carrier to prepare a colon-targeted delivery material. The W-PB is protected to be accurately delivered to the colon, the hydrogel is disintegrated to release the W-PB under the subsequent alkaline environment, and then W ions are further released, so that responsive release of the colon is achieved, and systemic toxicity of the W ions is avoided.

The invention relates to the technical field of image inversion, and provides a diffusion probability model-based image inversion method, which comprises the following steps of: firstly, carrying out noise addition on a real image based on a deterministic noise addition algorithm of a denoising diffusion implicit model to generate an implicit vector; secondly, regarding a text embedding vector generated by corresponding text description as an optimizable variable; then, inputting the text embedded vector and the implicit vector into a stable diffusion model together, and performing a denoising process based on a denoising algorithm of a denoising diffusion implicit model to obtain a reconstructed image; and finally, adopting a root-mean-square error between the reconstructed image and the real image as an optimization loss function, and optimizing a text embedding vector through a gradient descent algorithm so as to realize high-precision reconstruction of the real image.

This disclosure relates to a cleaning control method, apparatus, device, medium, and program product for a robotic vacuum cleaner. According to an example of this disclosure, the method includes: displaying an initial work area map in a user interface; in response to receiving a shape editing instruction for an ultrasonic carpet area, editing the shape of the ultrasonic carpet area according to the editing method indicated by the shape editing instruction to obtain a target work area map; and sending the target work area map to the robotic vacuum cleaner for cleaning based on the target work area map. This disclosure enables flexible and accurate editing of the shape of the ultrasonic carpet area in the robotic vacuum cleaner's work area map according to user-triggered shape editing instructions, improving the accuracy of the ultrasonic carpet shape and thus enhancing the subsequent cleaning effect of the robotic vacuum cleaner.

The present invention provides a sgRNA for targeted knockout of bovine mammary epithelial cell TARDBP gene and a cell line constructed thereof. The sgRNA includes sgRNA1 and sgRNA2, and the nucleotide sequences of the sgRNA are shown in SEQ ID NO:1 and SEQ ID NO:2, respectively. The sgRNA of the present invention can accurately guide the Cas9 protein to target and cut the bovine mammary epithelial cell TARDBP gene, and the expression vector cell conversion rate obtained by constructing the sgRNA is high, which greatly improves the success rate of knocking out the bovine mammary epithelial cell TARDBP gene, and obtains the TARDBP gene knockout mammary epithelial cell line. In order to facilitate the study of the function and mechanism of the TARDBP gene in milk fat secretion and milk production of dairy cows, a cell model is provided, which lays the foundation for dairy cow biological breeding.

The application provides a T cell receptor and application thereof, and particularly relates to a T cell receptor (TCR) capable of specifically recognizing a glioblastoma-associated antigen and application thereof, wherein the glioblastoma-associated antigen can form a complex with HLA-A*0201 and be presented to the surface of a glioblastoma cell. The T cell of a patient is reformed into a cytotoxic T cell (TCR-T) specific to the GB-associated antigen. When the gene-edited TCR-T cell is input into the patient, the TCR-T cell specific to the GB-associated antigen is activated by specific recognition when encountering the antigen complex on the tumor cell, thereby expanding in the patient and achieving the effect of treating the tumor by killing the tumor cell. The application provides a new way for treating glioblastoma.

The present application relates to the technical field of genetic engineering, and more particularly to a super mini gene editor and application thereof. The present application first performs an engineering operation of simplifying the functional domain of a TnpB editor, and systematically develops a new super mini editor of 380-400 AA. The super mini new editor of the present application can efficiently realize precise and efficient editing from mammalian cells to living animals, and has great application value.

The invention relates to the technical field of dental medicine, in particular to a buccal width editing method and device of a dental model, equipment and a storage medium. The method comprises the following steps: acquiring a tooth model; the tooth model is initialized, target data of the tooth model are determined, and the target data comprise an initial buccal width feature value of the tooth model; determining a target buccal width characteristic value input by the user; constructing a deformation parameter according to the target data and the target buccal width characteristic value; and according to the deformation parameters, performing deformation processing on the tooth model through a grid-based Laplace deformation method. According to the method, an initial buccal width characteristic value of a tooth model is calculated, and a target buccal width characteristic value input by a user in real time is combined to construct a deformation parameter of Laplacian transformation, that is, the tooth model conforming to the target buccal width characteristic value is generated in a grid-based Laplacian transformation mode; accurate and fast editing of the buccal width features of the tooth model is realized.