The invention discloses a spherical-like fruit picking robot based on machine vision and a fruit picking method thereof. The spherical-like fruit picking robot comprises a picking device, a collecting device, a driving device, a console and a telescopic hose, the picking device comprises a mechanical arm base, a base rotating motor, a mechanical arm device, an end effector, an internal visual sensor, a large fruit shearing device, a small and medium fruit clamp and an external visual sensor, the end effector is connected with the collecting device through the telescopic hose, and the picking robot controls the picking device, the driving device and the collecting device to work through the console so as to complete fruit picking operation. According to the fruit picking robot, efficient picking of spherical-like fruits such as apples, pears, oranges, lemons, grapefruits, durians, kiwi fruits and grapes which grow and are distributed sparsely can be achieved, the cost performance of the picking robot is greatly improved, the fruit picking cost is reduced, and the fruit picking quality is greatly improved.