The invention relates to a moxibustion instrument, in particular to an open fire smoke cleaning moxibustion instrument, which comprises a combustion part, a driving part and an air outlet part, wherein the combustion part, the driving part and the air outlet part are sequentially communicated. The combustion part comprises a combustion chamber body, a heat insulation ventilation layer and a shellbody, wherein the combustion chamber body is arranged in the middle of the combustion part, the heat insulation ventilation layer is arranged surrounding a periphery of the combustion chamber body, aside wall of the combustion chamber body is provided with a hole; the shell body comprises a combustion chamber inner wall and a combustion chamber outer wall, an outer layer of the heat insulation ventilation layer is fixedly attached to the combustion chamber inner wall, and the combustion chamber outer wall is arranged at an outer side of the combustion chamber inner wall. By the adoption of the open fire smoke cleaning moxibustion instrument, substances generated after burning of wormwood are subjected to graded filtration through a precipitation suction chamber, so that wormwood oil is adsorbed on an absorption medium on a filter element, a separation process of smoke and gas is realized, and the open fire smokeless effect is achieved.