The invention discloses a hub main nut screwing and bearing pre-tightening force measuring machine. The machine comprises a front sealing plate, a rear sealing plate, an operating handle, a protecting hood, a guide post, a suspension device, a nut screwing shaft, a gear, a revolution measurement rotating shaft, a first servo motor, a second servo motor, a special sleeve and a revolution measurement wrench; and the screwing of hub main nut and detection of bearing pre-tightening force can be simultaneously realized through one hub main nut screwing and bearing pre-tightening force measuring machine and various schemes for screwing and measurement are simultaneously provided for a user to select, so that the machine is easy and convenient to operate, has high assembly precision, uniform torque, and high measurement accuracy, is time-saving and labor-saving, achieves automatic unmanned operation and saves labor cost.