113 results about "Circadian process" patented technology

The present invention provides a light emitting device comprising a first light emitting portion that emits white light at a color temperature of 6000K or more and a second light emitting portion that emits white light at a color temperature of 3000K or less, which include light emitting diode chips and phosphors and are independently driven. The present invention has an advantage in that a light emitting device can be diversely applied in a desired atmosphere and use by realizing white light with different light spectrums and color temperatures. Particularly, the present invention has the effect on health by adjusting the wavelength of light or the color temperature according to the circadian rhythm of humans.

Environmental characteristics of habitable environments (e.g., hotel or motel rooms, spas, resorts, cruise boat cabins, offices, hospitals and/or homes, apartments or residences) are controlled to eliminate, reduce or ameliorate adverse or harmful aspects and introduce, increase or enhance beneficial aspects in order to improve a “wellness” or sense of “wellbeing” provided via the environments. Control of intensity and wavelength distribution of passive and active Illumination addresses various issues, symptoms or syndromes, for instance to maintain a circadian rhythm or cycle, adjust for “jet lag” or season affective disorder, etc. Air quality and attributes are controlled. Scent(s) may be dispersed. Hypoallergenic items (e.g., bedding, linens) may be used. Water quality is controlled. Noise is reduced and sounds (e.g., masking, music, natural) may be provided. Passive and active pathogen controls are employed. Controls are provided for the occupant and/or facility personnel, as is instruction, and surveys, including assessing wellness.

This is a new invention, including improvements upon existing inventions, which is safer, simpler to use, less invasive into a user's daily routine and provides a lower cost solution to existing pulsed magnetic field and related vibrational electromagnetic therapy devices. This invention (apparatus) is referred to as an EnergyWave Therapy Device to distinguish it from existing electromagnetic therapy devices. It operates non-invasively on a homeopathic level to improve sleep, encourage natural healing and reduce pain, swelling, and general discomfort. This is accomplished through different embodiments of the apparatus all of which generate Multiple Simultaneous Extremely Low Frequency (MSELF) energy waves which may be any combination of Alternating Polarity Magnetic Fields (APMF), narrowband near-coherent long-wavelength (580 nm to 980 nm) light emitting diodes (LEDs), or electrical vibrations transmitted through the medium of water using carbon rod electrodes. The MSELF vibrations are derived from a quartz crystal with a fundamental frequency less than one-half of one percent from a natural Fibonacci Sequence Number. The apparatus utilizes firmware operating in a microcontroller containing predefined, user selectable therapy programs either emulating natural Circadian Rhythms for sleep and rest, or other therapeutic programs, all of which contain Electromagnetic Field (EMF) dose limitations to prevent any possible overexposure. The microcontroller is also clocked at the same fundamental frequency generated by the Fibonacci Sequence Quartz Crystal. Additionally, the apparatus's unique application of an H-Bridge configuration power-driver with Pulse Width Modulation (PWM) capabilities supports a novel approach to supply two simultaneous therapeutic frequencies to either a copper-trace coil emitter integrated on the main Printed Circuit Board (PCB) or optional external energy emitters. The result is a more effective, lower energy, safer, lower cost, simpler to use, noninvasive, multi-modal, EnergyWave Therapy Device.

A unit dosage form, such as a capsule or the like, for delivering drugs into the body in a circadian release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release drug delivery system is designed to provide a plasma concentration-time profile, which varies according to physiological need at different times during the dosing period, i.e., mimicking the circadian rhythm and severity/manifestation of gastric acid secretion (and/or midnight gerd), predicted based on pharmaco-kinetic and pharmaco-dynamic considerations and in vitro/in vivo correlations.

Systems and methods for treating diseases, addictions and disorders in humans and animals involving synchronizing and tailoring the administration of drug compounds with the body's natural circadian rhythms, in order to counteract symptoms when they are likely to be at their worst. Automated and pre programmable transdermal drug administration system are used. This system can also utilize a pump or pressurized reservoir, and/or a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with micro-fabricated structures commonly referred to as Micro-needles, or heat, or iontophoresis, sonophoresis, or a wide range of chemical permeation enhancers.

This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy utilizing a GCR antagonist, such as ORG 34517. The rapid, sensitive, and inexpensive test can be used to determine patients who have non-normal cortisol production or disordered circadian rhythms as a method for selecting subjects for GCR antagonist therapy for whom it is likely to have beneficial and/or therapeutic effects, and can also be used to monitor changes in cortisol levels in response to treatment.

A unit dosage form, such as a capsule or the like for delivering drugs into the body in a circadian release fashion, is comprising of one or more populations of propranolol-containing particles (beads, pellets, granules, etc.). Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release cardiovascular drug delivery system is designed to provide a plasma concentration-time profile, which varies according to physiological need during the day, i.e., mimicking the circadian rhythm and severity/manifestation of a cardiovascular disease, predicted based on pharmaco-kinetic and pharmaco-dynamic considerations and in vitro/in vivo correlations.

The present invention provides a non-addictive composition for the treatment of sleep disorders and problems including melatonin, valerian root extract, an antioxidant component, and a vitamin complex component. The present invention further provides a non-addictive composition for the treatment of sleep disorders and problems including melatonin, valerian Root Extract, proanthocyanidin, vitamin E, vitamin B₃, vitamin B₆, vitamin B₁₂, L-theanine, and magnesium. The present invention also provides a method for treating sleep disorders or problems of a human including administering a non-addictive composition for the treatment of sleep disorders or problems comprising a melatonin, valerian root extract, an antioxidant component, and a vitamin complex component; and causing the circadian rhythm of the human to be normalized and regulated, causing the sleep patterns of the human to be healthy and normal, and causing reduction of stress and anxiety in the human.

The invention discloses a lighting lamp control device which comprises a remote-control transmission circuit, a master control circuit and a drive circuit, wherein the remote-control transmission circuit transmits adjusting signals for adjusting color temperature and luminance of a lighting lamp; the master control circuit decodes the received signals transmitted by the remote-control transmission circuit and transmits the adjusting signals after responding to the adjusting signals of the remote-control transmission circuit; and the drive circuit controls the duty ratio of output PWM (pulse-width modulation) signals to adjust the luminance of the lighting lamp according to an adjusting signal instruction provided by the master control circuit and realizes color temperature adjustment according to different mixed light proportions. The lighting lamp control device and the lighting system have the advantages that illumination level of a ward can be adjusted according different time periods such as in the morning, at noon and at night, a biological rhythm change process is simulated, and illumination intensity and light source color temperature in different time periods can be set according to circadian rhythm demands, so that the illumination intensity and the light source color temperature of the ward can be naturally changed, an optimal rehabilitation lighting effect needed by a patient is achieved, and rehabilitation efficacy of the ward is improved.

The present invention has been made based on the finding that a compound acting on the ORL-1 receptor as an agonist acts as a non-photic entrainment factor, and advances the circadian rhythm phase, and provides a novel therapeutic agent for a sleep disorder such as circadian rhythm sleep disorder, more particularly, an agent for the prophylaxis and/or treatment of a sleep disorder, which contains an ORL-1 receptor agonist, and a novel compound useful as such agent for the prophylaxis and/or treatment.

Methods and compositions for modulating the circadian rhythm of a subject are provided. In practicing the subject methods, modulation of the circadian rhythm of a subject is achieved by administering to the subject an effective amount of at least one of a glucocorticoid receptor antagonist, a CRH antagonist and an MR agonist. Also provided are kits for practicing the subject methods.

The invention relates to an eye protection desk lamp with a light-emitting diode (LED) light source. The eye protection desk lamp with the LED light source comprises a base, a lamp shade, a connecting body of which the two ends are respectively connected with the base and the lamp shade, a light-emitting body which is arranged in the lamp shade, a driving power supply which is electrically connected with the light-emitting body, and a control device for controlling the driving power supply. The light-emitting body is an LED combined light source and at least comprises a first sub-light source and a second sub-light source, a circadian rhythm-photopic vision (C/P) value of first sub-light source emergent light is more than 2.5, the C/P value of second sub-light source emergent light is less than 2.5, and the control device controls the C/P value of light-emitting light source emergent light to be between the C/P value of the first sub-light source emergent light and the C/P value of the second sub-light source emergent light or to be equal to one of the C/P values. The eye protection desk lamp with the LED light source has the substantial characteristics that: by controlling the intensity of the light of all the sub-light sources of the combined light source, the final total C/P value of the combined light source and the intensity of the light are controlled to change along with the variation of time, the effect of simulating natural light is achieved, and the eye protection desk lamp with the LED light source adapts to the physiological cycle variation of human bodies.

A portable, disposable, and self-contained medical device for the production and delivery of therapeutic light to the blood transmitted through the non-ocular skin surface. The light is generated by a chemiluminescent dye configured to radiate light in the specific wavelength required by a particular phototherapy treatment. The wavelength of light emitted by this planar device is such that some disorders of health requiring phototherapy are effectively treated. Disorders falling into this category include elevated bilirubin jaundice, circadian rhythm anomalies, mood disorders and potentially a reduction in injury or surgically related bruise healing time.

The invention discloses a vehicle-mounted device having a driving complete period fatigue level real-time identification and early warning function. The device mainly comprises the following modules: a cumulative driving duration acquisition module which is used for judging the cumulative operation state duration of the vehicle and determining the cumulative driving duration of the driver; a workload acquisition module which is used for judging the high-speed driving cumulative workload of the driver; a GPS module which is used for accurately judging the current moment information; a circadian rhythm acquisition module which is used for judging the circadian rhythm cumulative degree of fatigue of the current driver through a moment information circadian rhythm table; a fatigue degree value calculation module which obtains the fatigue degree value of the driver of any moment; and an early warning module which is used for giving fatigue early warning information. According to the vehicle-mounted device, fatigue level judgment can be performed on any time period in the driving process so that the traffic accident can be reduced to a certain extent, the hazard caused by the traffic accident can be reduced and driving of the driver and public traveling are enabled to be safer.

The invention discloses a circadian rhythm analysis method and belongs to the technical field of human activity analysis. The method includes the steps that firstly, a three-axis acceleration sensor is used for continuous acquisition and downsampling, and three-axis activity amount data of a user is obtained; secondly, according to the three-axis activity amount data, the time when the user goes to bed and the time when the user gets up are obtained; thirdly, the three-axis activity amount from the time when the user goes to bed to the time when the user gets up is intercepted to serve as a sleep data segment; fourthly, sleep characteristic values in the sleep data segment are obtained through analysis; fifthly, according to the sleep characteristic values, the sleep state of the user in the sleeping process is obtained through judgment; sixthly, according to the sleep state, a corresponding circadian rhythm analysis result is output. According to the technical scheme, the method has the advantages that activity time nodes of the circadian rhythm can be more accurately determined, automatic judgment and analysis of the circadian rhythm can be achieved, and perfect reference and suggestions are provided for people to work and rest regularly and live a routine life.

The invention relates to a method for realizing the low blue light hazard and high circadian rhythm factor light, and an LED light source. The method is advantaged in that the yellow phosphor and thegreen phosphor are excited by a blue chip and a violet chip of different main wavelength ranges to form the light. The method is advantaged in that the obtained light can not only reduce visual fatigue, but also reduce the blue light hazard, can further adjust the circadian rhythm factor, improve students' attention and enhance learning efficiency. According to the method described above, the LEDlight source can form the light with the low blue light hazard and the high circadian rhythm factor in the optical theory, in the structural process, the yellow phosphor, the green phosphor and the encapsulant are mixed, and uniformly coated on surfaces of the blue chip and the violet chip through the centrifugal process to uniformly excite the phosphor, a cup wall of a reflector cup is plated with silver, light reflection is improved, and the light output rate is improved.

The invention discloses an LED light source control system applied to fish tanks. The LED light source control system comprises a light source controller, a plurality of LED projector lamps and a computer, wherein each LED projector lamp comprises a short-wavelength LED chip, the light source controller comprises a microprocessor, a clock unit and a serial communication interface unit, the clock unit and the serial communication interface unit are connected with the microprocessor, the microprocessor is used for storing growth and development parameters of living beings in the fish tanks and adjusting light intensity of the LED projector lamps according to the parameters, and the computer is used for setting the parameters stored in the microprocessor. By the LED light source control system, aquiculture growth efficiency of fish is improved, yield of marketable fish is increased, circadian rhythm, feeding behaviors and gonad development of the can be improved, and green and high-quality protein food is obtained.