287 results about "Cyclobutanes" patented technology

A process for preparing a polymer comprising sulfonating a perfluorocyclobutane polymer with a sulfonating agent to form a sulfonated perfluorocyclobutane polymer, wherein the sulfonating agent comprises oleum or SO₃ is provided. A process for preparing proton exchange membranes and fuel cells comprising the proton exchange membrane are also provided.

This invention enables forming a photo-alignment film having a large LC anchoring strength in an IPS type liquid crystal display device. An alignment film is adapted to have a two-layer structure including a photo-alignment film and an alignment film with enhanced film strength. The photo-alignment film is formed of a precursor of polyamide acid ester, 80 percent or more of which is polyamide acid ester including cyclobutane. The alignment film with enhanced film strength is formed of a precursor of polyamide acid. After irradiating the substrate with ultraviolet light for photo-alignment, the substrate is heated. Thus, it is possible to achieve a high LC anchoring strength of the alignment film as the whole for photo-alignment, without degrading the mechanical strength of the alignment film with enhanced film strength.

The radiolabeled non-natural amino acid 1-amino-3-cyclobutane-1-carboxylic acid (ACBC) and its analogs are candidate tumor imaging agents useful for positron emission tomography and single photon emission computed tomography due to their selective affinity for tumor cells. The present invention provides methods for stereo-selective synthesis of syn-ACBC analogs. The disclosed synthetic strategy is reliable and efficient and can be used to synthesize a gram quantity of various syn-isomers of the ACBC analogs, particularly, syn-[¹⁸F]-1-amino-3-fluorocyclobutane-1-carboxylic acid (FACBC) and syn-[¹²³I]-1-amino-3-iodocyclobutane-1-carboxylic (IACBC) acid analogs.

The invention relates to a method for preparing a lobaplatin trihydrate by using oxalate, diaminomethyl cyclobutane oxalate, potassium chloroplatinite and potassium iodide are taken as raw materials, and the method comprises the following steps: firstly replacing the potassium chloroplatinite to potassium iodoplatinite, neutralizing the oxalic acid in diaminomethyl cyclobutane under alkaline condition, enabling the diaminomethyl cyclobutane to be freed, and then reacting the diaminomethyl cyclobutane with K2PtI4 (potassium iodoplatinate) for synthesizing a diiodide; enabling the diiodide to carry out replacement reaction with silver nitrate to generate silver iodide precipitate, enabling reactants after filtering out the precipitate to carry out ion exchange with anion exchange resin, then synthesizing a lobaplatin anhydride with lactic acid, re-crystallizing the anhydride in water/acetone mixed solution, and finally obtaining a lobaplatin trihydrate product. The raw materials used in the method have stable performances, the reaction is fuller and more complete, and the yield of the lobaplatin trihydrate is high.

The invention provides liquid crystal alignment agents for photo-alignment, liquid crystal photo-alignment layers, and liquid crystal displays using the same. The liquid crystal alignment agents contain tetracarboxylic dianhydride mixture including cyclopentane tetracarboxylic dianhydride, which is reacted with specific diamine to obtain polyamide acid or its derivatives. The liquid crystal alignment agents are applied to form a photo-alignment film with excellent alignment property and high light transmittance, because of light sensitivity of the chemical change caused by illumination. In addition, the photo-alignment film is applied in liquid crystal displays, the electrical characteristics required by liquid crystal alignment film is satisfied, the voltage maintaince ratio is high, the iron amount is little, the remained charge amount is little, etc.

Provided is a liquid crystal alignment film which suppresses afterimages caused by AC drive in an IPS- or FFS-driven liquid crystal display element, and which exhibits fast relaxation of residual charges accumulated by DC voltage. Also provided is a liquid crystal aligning agent suitable for use in a photo-alignment process in order to obtain the liquid crystal alignment film. The liquid crystal aligning agent suitable for use in a photo-alignment process comprises: at least one polymer (component (A)) selected from polyamic acid and imidized polyamic acid polymers obtained by reacting a tetracarboxylic dianhydride provided with a specific structure having a cyclobutane backbone, and a diamine compound that has at least one diamine selected from the group having the structures represented by formulae (D-1) and (D-2), and that has an amino group protected by a thermally cleavable group which is replaced by hydrogen at heating; at least one polymer (component (B)) selected from polyamic acid and imidized polyamic acid polymers obtained by reacting a tetracarboxylic dianhydride and a diamine compound which contains a diamine having a nitrogen-containing aromatic heterocycle such as pyridine; and an organic solvent.

The invention relates to a liquid crystal aligning agent, a liquid crystal aligning film and a liquid crystal display element. The invention provides a liquid crystal aligning agent which is provided with an excellent pretilt angle property by an optical alignment method, and can form a liquit crystal aligning film which does not result in poor display performance even when drived continuously for a long time. The liquit crystal aligning agent contains: (A) polyamide acid A, which is obtained by allowing tetracarboxylic dianhydride to react with diamines containing a diamine with a photoreactive structure; (B) polyamide acid B, which is obtained by allowing at least one tetracarboxylic dianhydride selected from a group composed of 1, 2, 3, 4-cyclobutane tetracarboxylic dianhydride, pyromellitic dianhydride to react with at least one diamine selected from a group composed of 2, 2'-dimethyl-4, 4'-diaminobiphenyl, p-phenylenediamine, 4, 4'-diaminodiphenylmethane, 4, 4'-diaminodiphenyl ether (with the polyamide acid A excluded).

The multicomponent mixed work medium throttling refrigerating agent applicable to 200-240 k temp. zone includes four groups of substances, respectively are: first group includes tetrafluoromethane, nitrogen trifluoride or mixture; second group includes ethylene, ethane, fluoroform, xenon, fluromethane, perfluoroethylene, fluoroethylene, perfluoroethane or their any two, three and several kinds or mixture of all them; fourth group includes 1-butylene, isobutane, 2-methyl butane, 1-pentene, 3-methyl-1-butylene, 2-methylpentane, 2-butylene, cyclobutane, isobutylene, n-butane, pefluorobutane, n-pentane, perfluoropentane or their two, three, several kinds ormixture of all the them; and third group includees propylene, propane, perfluoropropane, 1,1,1-trifluoroethane, 1,1,-bifluoroethane.

The present invention provides Mannich base derivatives of N,N′-dimethyl secondary diamine polymers including Mannich base derivatives of methylamine-terminated poly-(N-methylazetidine) and Mannich base derivatives of methylamine-terminated poly-(N-methylazacycloheptane). Amine curing agent compositions and amine-epoxy compositions containing Mannich base derivatives of N,N′-dimethyl secondary diamine polymers are also disclosed.

The invention provides a novel preparation method of Apalutamide. According to the novel preparation method, 2-fluoro-4-bromo-N-methyl benzene methanamine amide, 1-amino cyclobutyl carboxylate hydrochloride, and the like are taken as initial raw materials, and substitution reaction is carried out so as to obtain 1-((3-fluoro-4-(methyl carbamyl)phenyl)amino) cyclobutane-1-carboxylic acid, wherein synthesis yield is higher than 70%, and purity is higher than 97.2%; then esterification is carried out so as to obtain 1-((3-fluoro-4-(methyl carbamyl)phenyl)amino) cyclobutane-1-carboxylic ester, wherein synthesis yield is higher than 83%, and purity is higher than 97.8%; and at last, ring closing reaction with 2-cyan-3-trifluoromethyl-5-isothiocyano pyridine is carried out so as to obtain Apalutamide, wherein yield is higher than 68%, and purity is higher than 98.1%. The preparation method possesses following advantages: the raw materials are easily available; technology is simple; operationis convenient; yield is high; and cost is low.

The present invention discloses one kind of multicomponent mixture work medium suitable for fractional condensation type heat pump circulation system. The mixture work medium or mixed refrigeratant consists of two components, including one low boiling point component and one high boiling point component. The low boiling point component is one or several selected from difluro methane, trifluoro ethane, fluoro ethane, propylene, propane, pentafluoro ethane, etc. The high boiling point component is one or several selected from isobutane, n-butane, butene, isobutene, octafluoro isobutene, octafluoro cyclobutane, etc.

The invention provides a preparation method of lobaplatin and lobaplatin trihydrate. Trans-diamine methyl cyclobutane reacts and synthesizes with chloroplatinite in water at the atmosphere of inert gas to generate dichloride, wherein the trans-diamine methyl cyclobutane and the chloroplatinite are taken as raw materials, and the water serves as a solvent; replacement reaction is performed on the dichloride and silver nitrate, so that silver chloride sediments are generated after filtration; filter liquor reacts with L-lactic acid and/or L-lactate under a certain pH value condition so as to generate the lobaplatin; then water/acetone recrystallization is performed on the lobaplatin, so that high-purity lobaplatin trihydrate is obtained. The preparation method provided by the invention includes few reaction steps, and is short in reaction time, high in reaction efficiency, easy and convenient to operate and suitable for industrial production.

The invention relates to furan dicarboxylic acid copolyester and a preparation method thereof. The furan dicarboxylic acid copolyester has a structural formula as shown in a following formula (1), wherein x, y and z are integers of 10-90. The preparation method comprises the following steps: (1) mixing a dibasic acid or ester of the dibasic acid, dihydric alcohol and an esterification catalyst, and performing an esterification reaction in an inert atmosphere so as to obtain a first intermediate product, wherein the dibasic acid comprises furan dicarboxylic acid, and the dihydric alcohol includes ethylene glycol, 1,4-cyclohexane dimethanol and 2,2,4,4-tetramethyl-1,3-cyclobutane dimethanol; (2) performing a pre-polycondensation reaction on the first intermediate product under vacuum conditions so as to obtain a second intermediate product; and (3) performing a polycondensation reaction on the second intermediate product under vacuum condition so as to obtain the furan dicarboxylic acidcopolyester. The preparation method is simple, and the obtained furan dicarboxylic acid copolyester has excellent heat resistance, transparency and mechanical properties at the same time, and can be used for manufacturing baby nursing bottles, children toys, cups, kitchen utensils, electronic appliances and other products.

The invention relates to a radiation ray sensitive composition, a colour filter and a liquid crystal display used to form a coloured coat. The radiation ray sensitive composition used to form a coloured coat is characterized in that the composition contains (A) a pigment, (B) dispersant of which at least one of acid value and ammonia value is more than 0, (C) alkali soluble resins, (D) a multifunctional monomer, (E) optical polymerization initiator and (F) a polymer with repeated unit content of oxacyclobutane more than 70%. Even at a post-baking temperature of less than 200 DEG C, radiation ray sensitive composition used to form a coloured coat can form pixels and a black matrixes which are good in acid resistance to wide range of solvent and have good tightness with base plates.

A transparent polyimide film, prepared from a copolymerized polyamide acid according to a chemical cyclization method, is provided. The copolymerized polyamide acid requires at least a semi-aromatic polyamide acid, and the semi-aromatic polyamide acid is formed by reacting cyclobutane-1,2,3,4-tetracarboxylic dianhydride (CBDA) and 2,2′-bis(trifluoromethyl)diaminodiphenyl (TFMB). The molar number of dianhydrides of the semi-aromatic polyamide acid is more than 20% of the total molar number of anhydrides of the copolymerized polyamide acid, so that the transparent polyimide film has a light transmittance greater than 80%, a chroma b* less than 5, and a CTE less than 35 ppm/° C.