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3 results about "Electropherogram" patented technology
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An electropherogram (or electrophorogram) is a record or chart produced when electrophoresis is used in an analytical technique, primarily in the fields of molecular biology or biochemistry. In the field of genetics, an electropherogram is a plot of DNA fragment sizes, typically used for genotyping such as DNA sequencing. Such plots are often achieved using an instrument such as an automated DNA sequencer. Such electropherograms may be used to determine DNA sequence genotypes, or genotypes that are based on the length of specific DNA fragments.
Method for analyzing sample comprising hemoglobin A2 by capillary electrophoresis
Provided is a method for analyzing a sample comprising hemoglobin A2 by capillary electrophoresis using an alkaline aqueous solution comprising a cationic polymer, which is the analysis method including the following steps: 1) obtaining an electropherogram of the sample by capillary electrophoresis; 2) specifying a detection time Tx of an X peak; 3) specifying a detection time Ta2 of an HbA2 peak; 4) specifying a detection time Ty of a Y peak; 5) calculating a correction coefficient from a relative relationship of the detection time Tx, Ta2, and Ty; 6) calculating a ratio of an HbA2 peak area to a total peak area or a ratio of a Y peak area to the total peak area in an electropherogram; and 7) correcting the ratio of the HbA2 peak area or the ratio of the Y peak area with the correction coefficient.
Owner:ARKRAY INC
A method for detecting endogenously synthesized immunoglobulins in the central nervous system based on MALDI-TOF MS
The application belongs to the technical field of in-vitro detection, and particularly relates to a detection method of endogenous synthesis immunoglobulin in central nervous system based on MALDI-TOF MS. The application provides a kit for detecting and typing immunoglobulin in a sample and a method for detecting immunoglobulin in a sample, and solves the problems of low detection method flux, complicated experimental process, long time consumption, high experience requirement for detection personnel, and result interpretation being easily affected by electropherogram background of isoelectric focusing electrophoresis combined with immunofixed oligoclonal band electrophoresis (OCB) technology. The detection method provided by the application is more accurate, simpler to operate and easier to realize automation, has no subjective problems of manual interpretation, has lower detection cost, has higher detection flux, and is easier to popularize in clinical diagnosis and treatment.
Owner:RONGZHI BIOTECHNOLOGY CO LTD +1
Cancer risk prediction method based on capillary electrophoresis fragment characteristics of cell-free DNA
The present invention relates to methods for determining the concentration of cell-free DNA (cfDNA) from capillary electropherogram and calculating the proportion of short fragments from mono-nucleosomes. In some embodiments, the determination of cfDNA concentration and mono-nucleosome short fragment proportion, optionally in combination with a panel of screened protein biomarkers, can be used to achieve efficient and cost-effective early detection of multiple cancer types.
Owner:H & H WORKS LTD +1