67 results about "Enone" patented technology

The invention belongs to the technical field of organic matter preparation, and particularly relates to a preparation method of 2-pentylcyclopentyl-2-ketene. According to the method, methanol is used as a solvent, sulfonic acid type resin doped with lewis acid is used as a catalyst to catalyze the isomerization reaction of 2-pentylidene cyclopentanone, the catalyst and the methanol solvent can jointly promote the isomerization reaction of 2-pentylidene cyclopentanone, and the catalytic efficiency is high, so that the reaction yield is remarkably increased, and the catalyst cost is reduced; in addition, a fixed bed reactor continuous production mode is adopted, waste salt is prevented from being generated when the acid catalyst is quenched by processes such as HCl / HBr / p-toluenesulfonic acid, and methanol is used as a solvent, so that the byproduct dimethyl ether is simply separated from water and the solvent methanol. In addition, when the sulfonic acid type resin doped with the lewis acid is used for catalyzing the isomerization reaction of 2-pentylidene cyclopentanone, the stability is high, and the service life is long.

The invention provides a preparation method of polar polyolefin, and belongs to the technical field of polyolefin. The preparation method comprises the following steps: in an inert atmosphere, under the action of a catalyst and a cocatalyst, copolymerizing C2-C6 olefin and an alkylated polar monomer in an organic solvent to prepare polar polyolefin, wherein the alkylated polar monomer is prepared by the following steps: dissolving an alkylating reagent in an organic solvent, adding a polar monomer, and mixing and stirring to obtain the alkylated polar monomer; the polar monomer comprises at least one of halogenated alpha-olefin, alpha-olefine acid, alpha-enol, alpha-olefine aldehyde, alpha-olefine ester and alpha-olefine ketone. The polar monomer is pre-protected by adding the alkylating reagent, so that effective copolymerization of C2-C6 olefin and the polar monomer is realized, and the performance of polyolefin is favorably improved.

The application provides a reverse Markovnikov hydroamination reaction of trifluoromethyl enone under catalyst-free and base-free conditions, uses a sulfonhydrazide compound with good functional group tolerance as a nitrogen source, realizes the introduction of a nitrogen-containing functional group in a green and environment-friendly manner, and synthesizes a series of alpha-sulfonhydrazine-alpha-hexafluoroisopropyl-substituted carbonyl compounds. The method has the characteristics of no transition metal participation, mild conditions, wide substrate universality and the like.

The application belongs to the technical field of chemical synthesis, and particularly relates to a synthesis method of 2-aryl-2-cyclohexanedione enol ester compounds. The method uses a transition metal complex as a catalyst, and uses a phenyl boronic acid compound and an iodine onium compound as raw materials, first synthesizes a 3-hydroxy-2-aryl-2-cyclohexenone compound, and then synthesizes the 2-aryl-2-cyclohexanedione enol ester compound through acylation. The reaction condition is mild, no additional additives (such as alkali-sodium acetate, expensive silver salt-silver acetate, etc.) need to be added, the C-C bond can be efficiently and quickly constructed, the 2-aryl-2-cyclohexanedione cyclization derivative is obtained, the reaction operation is simple, the reaction time is short, the method has high efficiency and high safety, the substrate range is wide, the functional group tolerance is good, the method conforms to the concept of green chemistry and high atomic economy, and is very suitable for large-scale industrial production.

The application relates to the technical field of chemical synthesis, and particularly discloses a method for constructing cycloalkanol by nickel-catalyzed asymmetric hydrogenation of tri-substituted enone, and a chiral alcohol prepared by the method. The method uses alpha, beta-unsaturated ketone with different molecular structures as a substrate to construct chiral alcohol with double chiral centers, hydrogen is added to reduce the enyl group first, and then hydrogen is added to reduce the carbonyl group. In the case that the hydrogen on the carbon in the conjugated ring is replaced by different substituents, good reduction effect can be obtained. The catalyst has simple preparation mode and stable performance, and good chiral selection effect and conversion rate can still be obtained under the condition of high substrate / catalyst.

The invention discloses a method for separating and preparing megastigmatrienone isomers, and belongs to the technical field of isomer separation and preparation. The technical problem to be solved is that in the prior art, mg-level separation preparation of a megastigmatrienone single-configuration isomer cannot be rapidly realized. The key point of the technical scheme is as follows: the method comprises the following steps: (1) mixing megastigmatrienone with methanol to obtain a mixed solution; (2) separating the mixed solution by adopting a reversed-phase preparative chromatography to obtain an isomer of megastigmatrienone; wherein the chromatographic conditions in the reversed-phase preparative chromatography in the step (2) are as follows: a chromatographic column is a reversed-phase semi-preparative chromatographic column, the sample size is 100-800 [mu] L, the flow velocity is 0.1-0.8 mL / min, the detection wavelength is 308 nm, an eluent is methanol-THF-H2O in a ratio of 37.5: 7.5: 55, and isocratic elution is performed.

This invention discloses a high-adhesion optical adhesive for extreme conditions, its preparation method, and its application, belonging to the field of optical adhesive technology. It comprises the following components in parts by weight: 20-30 parts of 2-methyl-6-methylene-1,7-octadien-3-one, 15-25 parts of 1,4-butanediol dimethacrylate, 15-25 parts of tetraethylene glycol dimethacrylate, 5-10 parts of α-methacrylic acid, 5-10 parts of hydroxyethyl methacrylate, 2-5 parts of vinyltriethoxysilane, 0.1-0.5 parts of 1-hydroxycyclohexylphenyl ketone, 0.1-0.5 parts of 2-hydroxy-2-methyl-1-phenyl-1-propanone, and 0.3-0.5 parts of 1-[9-ethyl-6-(2-methylbenzoyl)-9H-carbazole-3-yl]acetone-1-(O-acetyloxime). The optical adhesive of the present invention has excellent bonding performance and can prevent the bonded components from debonding and causing cohesive failure at the bonding joint in humid, steamy, or chemical solvent environments.

A first aspect of the invention relates to a mixture comprising 2,4- toluene diamine and 2,6-toluene diamine and comprising less than 10 weight-ppm of an amino methyl cyclohexenone compound of formula (I) based on the total weight of the mixture being 100 weight-%. In a second aspect, the invention is directed to a method for controlling a hydrogenation process for preparing toluene diamine (TDA) from dinitrotoluene (DNT), said TDA having a boiling temperature range BTRTDA with a lower boiling temperature limit value TTDA(L) and an upper boiling temperature limit value TTDA(U). A third aspect relates to a mixture comprising at least 2,4- toluene diamine and 2,6-toluene diamine obtained or obtainable from the method according to the second aspect. A fourth aspect of the invention is directed to a use of the mixture according to the first aspect of the invention or of the mixture of the third aspect of the invention for the preparation of toluene diisocyanate (TDI). In a fifth aspect, the invention relates to a process for preparing toluene diisocyanate (TDI) comprising: (I) Providing a mixture according to the first aspect of the invention or of the mixture of the third aspect of the invention; and (II) Phosgenation of the mixture provided in (I), thereby obtaining TDI.

The present application relates to a kind of high 4-HBC mycobacterium genetic engineering bacteria and its construction method, and its application in the microbial fermentation preparation 22-hydroxy-23, 24-bis-norcholesta-4-en-3-ketone of 4-HBC.The high 4-HBC mycobacterium genetic engineering bacteria is constructed as follows: with mycobacterium as chassis, kshA1, kshA2, kstD1, kstD2, kstD3 gene is knocked out in turn, hsd4A gene is knocked out, ltp3, ltp4 gene is overexpressed, and the high 4-HBC mycobacterium genetic engineering bacteria is obtained.The genetic engineering bacteria provided in the present application can produce 4-HBC, greatly improve the production efficiency of steroidal drugs, help to improve the conversion rate of substrate, reduce production cost, and reaction condition is mild, environment-friendly, suitable for vigorous popularization and application, with higher economic benefit and social benefit.

This invention discloses a method for the kinetic resolution of oxaspirone via organocatalytic hydrogenolysis. Using chiral phosphate CPA as a catalyst, Hantzsch ester as a hydrogen source, and racemic oxaspirone 2,4-dien-6-one rac-1 as a substrate, a series of axially chiral biaryl phenolic compounds 2 are synthesized via asymmetric hydrogenolysis, and the central chiral oxaspirone 1 is recovered. This invention offers advantages such as simple and practical operation, readily available raw materials, high resolution coefficient, and good enantioselectivity. Some of the axially chiral biaryl products have structures similar to axially chiral cannabinol, possessing potential medicinal value.

This invention discloses a method for the catalytic hydrolysis of 3,3'-oxybis(cyclohexane-2-en-1-one) using carbon materials. Under the action of a bio-carbon-supported potassium-magnesium oxide catalyst rich in strongly basic sites, 3,3'-oxybis(cyclohexane-2-en-1-one) undergoes a hydrolysis reaction to produce 1,3-cyclohexanedione. The raw material 3,3'-oxybis(cyclohexane-2-en-1-one) is a byproduct of the resorcinol process for preparing 1,3-cyclohexanedione, and is inexpensive and readily available. The catalytic hydrolysis of 3,3'-oxybis(cyclohexane-2-en-1-one) to produce 1,3-cyclohexanedione achieves value-added processing of byproducts from the CHD industry, reduces solid waste generation, lowers the production cost of 1,3-cyclohexanedione, and has significant socio-economic benefits.

The present invention relates to a process for the preparation of Halogenated Alkenone Ethers of Formula (1) from a compound of Formula (2) using an iodide- based catalyst which enables superior process performance in terms of throughput, yield, and product purity when compared to the prior art, in addition to making the process more environmentally friendly by enabling the use of environmentally benign, inexpensive inorganic bases - in lieu of environmentally damaging organic bases, as were used in the prior art.

The application discloses a synthetic method of preparing a plant source cholesterin key intermediate 20-formyl-pregn-4-ene-3-ketone. The method takes plant source 21-hydroxy-20-methyl-pregn-4-ene-3-ketone, also known as bisnorol or BA, as raw material, and oxidizes BA into aldehyde through a phase transfer catalyst under oxygen environment. The preparation method has the advantages of high yield, mild reaction condition, fast reaction time, cheap and recyclable solvent, relatively simple operation and the like, solves the problems of high production cost and serious pollution in the prior art, has high industrial production value and good agricultural application prospect, and provides a new method for synthesizing medicinal auxiliary materials of plant source cholesterin. The reaction formula is as follows.

The present application relates to the technical field of organic synthesis, in particular to a synthesis method of polysubstituted pyrazole compounds, which comprises adding aryl diazonium salt 0.6 mmol, enone 0.9 mmol, 0.5 ml of acid and 0.3 mmol of electrolyte into a 10 ml three-necked bottle, and then adding 6 ml of solvent to dissolve; using a carbon rod as an anode and a platinum plate as a cathode, stirring the reaction, monitoring the reaction process by using thin layer chromatography, after the reaction is completed, extracting the mixture with ethyl acetate; drying the organic layer of the mixture with anhydrous sodium sulfate, rotary evaporating the solvent under reduced pressure, purifying the residue by column chromatography, and obtaining the target product; the method uses aryl diazonium salt as a double synthetic substrate under mild electrochemical conditions, continuously generates two free radicals by electrochemical reduction of aryl diazonium salt, directly synthesizes a series of polysubstituted pyrazole compounds, directly and orderly constructs polysubstituted pyrazole compounds without transition metal or external redox agent, is environment-friendly, efficient and high in atom economy.

The present invention relates to a chiral iridium hydride complex comprising a) a chiral (P, N)-ligand and b) a stabilized ketene ligand of formula (I), wherein R1 is selected from the group consisting of hydrogen, a C1-C500-alkyl group, a C2-C500-alkenyl group, a C1-C500-alkoxy group, a C2-C500-alkenyloxy group, a C1-C500-alkylamino group, a C2-C500-alkenyl amino group, a di-(C1-C500-alkyl) amino group, a di-(C2-C500-alkenyl) amino group, a N-(C1-C500-alkyl)-N-(C2-C500-alkenyl) amino group, a C3-C8-cycloalkyl group, a C3-C8-cycloalkyloxy group, a C3-C8-cycloalkylamino group, a N-(C1-C500-alkyl)-N-(C3-C8-cycloalkyl) amino group, and a pharmaceutically acceptable salt thereof; a C6-C14-aryl group, which may be substituted as further defined in the specification; r1a is selected from hydrogen, C1-C6-alkyl, C1-C6-alkylcarbonyl, or R1a and R1 together with the carbon atom to which R1a is attached and the carbonyl to which R1 is attached form a C5-C7-cycloalkanone ring wherein the C5-C7-cycloalkanone ring is unsubstituted or substituted by 1 to 4 substituents independently selected from C1-C6-alkyl and benzylidene, wherein the benzylidene group is unsubstituted or substituted by 1 to 5 substituents independently of one another selected from the group consisting of halogen, a C1-C500-alkyl group, a C1-C500-alkoxy group, a C1-C500-haloalkyl group, and a C1-C500-haloalkoxy group; r2 is selected from hydrogen, a C1-C500-alkyl group, a C1-C500-alkoxy group, a C1-C500-alkylamino group, a di-(C1-C500-alkyl) amino group, a C3-C8-cycloalkyl group, a C3-C8-cycloalkyloxy group, a C3-C8-cycloalkylamino group, an N-(C1-C500-alkyl)-N-(C3-C8-cycloalkyl) amino group, a C6-C14-aryl group, which may be substituted as further defined in the specification; and arrow represents a bond attached to an iridium atom; the present invention relates to chiral iridium hydride complexes, and to a method for producing optically active 4-substituted 1, 2, 3, 4-tetrahydroquinolines by enantioselective hydrogenation of the corresponding 4-substituted 1, 2-dihydroquinolines in the presence of such chiral iridium hydride complexes.

The invention discloses a detoxification agent as well as a preparation method and application thereof, the preparation method comprises the following steps: (1) crushing cleaned and dried shrimp shells and / or crab shells, soaking with hydrochloric acid, centrifuging to obtain a first precipitate, and finally washing and drying the first precipitate to obtain a first dried substance; (2) performing firing, grinding, ultrasonic treatment and centrifugal treatment on the first dried substance to obtain a second precipitate, and then washing and drying the second precipitate to obtain a second dried substance; and (3) performing firing, ultrasonic treatment and centrifugal treatment on the second dried substance to obtain a third precipitate, and then washing and drying the third precipitate to obtain the detoxification agent. The detoxification agent disclosed by the invention can be used for efficiently removing harmful substances such as zearalenone and / or benzo [a] pyrene and the like.

The invention discloses a compound and a preparation method thereof, a perovskite solar cell, a power utilization device and a power generation device, the compound is used for an electron transport layer of the perovskite solar cell, the compound comprises a fullerene pyrrolidine group and an R group connected with the fullerene pyrrolidine group, the R group comprises an alkane group and a halogen group, and the halogen group is a halogen group. The alkyl group is at least one of an ether group, a sulfonyl group, a phosphoryl chloride group, a halogen ether group, a ketene group, an amide group and an amino ester group. The invention provides a new material capable of being used for an electron transport layer, and the perovskite solar cell containing the electron transport layer of the compound provided by the invention has the photoelectric conversion efficiency basically equal to or better than that of a perovskite solar cell with an electron transport layer formed by an electron transport material in related technologies. The compound has a relatively high oil-water distribution coefficient, and is beneficial to preparation of large-size perovskite solar cells.

This invention relates to the field of asymmetric catalytic hydrogenation, specifically to a method for preparing chiral chromone or chromane carboxylic acid compounds. The method involves preparing a chiral catalyst from a nickel compound and ligands. By controlling the combination of the nickel compound-ligand-solvent, enantioselective hydrogenation of the conjugated C=C bonds of the substrate chromone carboxylic acid compound is achieved, yielding the semi-reduced product chiral chromone carboxylic acid; or, further, the carbonyl group is reduced, and carbonyl reduction and dehydroxylation reactions are carried out at room temperature under trifluoroacetic acid and triethylsilane conditions to obtain the fully reduced product chiral chromane carboxylic acid. The catalytic system of this invention is simple to construct, and the selectivity can be controlled by the solvent system. It maintains high conversion and excellent enantioselectivity even under high S / C conditions, making it suitable for the efficient preparation of chiral chromone / chromane skeletal carboxylic acid compounds.

The invention discloses 6, 7-dihydrocyclopenta [b] pyridine-5-ketone and a synthesis method and application thereof.The method comprises the steps that a compound 1, namely 1, 3-cyclopentanedione, is added into an organic solvent I, ammonium acetate is added, the temperature is increased to 70-160 DEG C under inert gas protection, stirring reaction is conducted for 4-10 hours, after raw materials are consumed up, reaction liquid is subjected to first-time aftertreatment, and after the reaction liquid is subjected to second-time aftertreatment, a compound 2, namely 1, 3-cyclopentanedione is obtained; the compound 2 is 3-aminocyclopentyl-2-ketene; and adding the compound 2 obtained in the previous step, namely 3-aminocyclopentyl-2-ketene, into an organic solvent II, then adding p-methyl phenyl sulfonic acid hydrate, malonaldehyde and sulfate, heating to 60-150 DEG C under the protection of inert gas, stirring for 8-20 hours, and after the raw materials are completely consumed, carrying out secondary post-treatment on the reaction liquid to obtain a target compound 3, namely 6, 7-dimethoxy-2-(3-aminocyclopentyl-2-ketene). The invention relates to 2, 7-dihydrocyclopenta [b] pyridine-5-ketone.

The invention relates to a selective hydrogenation reduction method of a non-conjugated ketene compound, which comprises the following steps: in a nitrogen atmosphere, mixing a ketene compound shown as a formula (I), a hydrogen source, a catalyst, a ligand, a reducing agent and an organic solvent, and stirring at room temperature for 8-24 hours to obtain a reaction solution; and performing column chromatography separation and purification on the reaction liquid to obtain the alkyl ketone compound as shown in the formula (II). According to the method, iodoethane or bromoethane is used as a hydrogen source, and compared with the prior art, the method has the advantages of higher yield, mild reaction conditions, good selectivity, no need of high-pressure hydrogen, no pungent smell and environmental protection.

This invention provides a composition effective in suppressing the deterioration of citral flavor. [Solution] A citral flavor-suppressing composition containing one or more compounds selected from the group consisting of 8-methyl-4-methylenenona-7-en-2-one and 4,8-dimethylnona-3,7-dien-2-one as an active ingredient. Preferably, it contains at least 8-methyl-4-methylenenona-7-en-2-one. Alternatively, preferably, the unpleasant flavor is due to p-cresol and / or p-methylacetophenone.

This invention relates to a method for synthesizing squaric acid, the method comprising the following steps: (1) reacting alkyl vinyl ether, trichloroacetyl chloride, and zinc to obtain 2,2-dichloro-3-alkoxycyclobutanone; (2) subjecting 2,2-dichloro-3-alkoxycyclobutanone to chlorination with chlorine to obtain 2,2,4,4-tetrachloro-3-alkoxycyclobutanone; (3) subjecting 2,2,4,4-tetrachloro-3-alkoxycyclobutanone to elimination reaction with a base to obtain 2,4,4-trichloro-3-alkoxycyclobuten-1-one; and (4) subjecting 2,4,4-trichloro-3-alkoxycyclobuten-1-one to hydrolysis to obtain the squaric acid. The synthesis method provided by this invention avoids the use of the prohibited raw material perchloro-1,3-butadiene and has lower energy consumption, meeting the needs of green and clean production.

The present invention provides an estetrol synthesis process, and relates to the technical field of steroid compound synthesis processes, and the method comprises the following steps: taking estrone as an initial raw material, firstly carrying out 3-site hydroxyl protection, and then carrying out an oxidative dehydrogenation reaction in the presence of a metal catalyst and in an oxygen atmosphere to prepare a key intermediate ketene, then 17-site carbonyl reduction, 17-site hydroxyl protection, 15, 16-site double bond dihydroxylation, 3-site protecting group removal and hydrolysis reaction are sequentially carried out, and finally the target product estetrol is obtained. The method adopts metal catalysis to directly oxidize to construct cycloenone, effectively avoids the problem of poor stability of partial intermediates in the prior art, has the advantages of simple process, short reaction steps, greenness, environmental protection and the like, and is suitable for industrial production.

The invention discloses ketene reductase and a method for preparing (R)-4-propyl-dihydrofuran-2-ketone by using the ketene reductase, the amino acid sequence of the ketene reductase has at least 95%, 96%, 97%, 98% or 99% identity compared with the amino acid sequence shown in SEQ ID NO: 1, and at least one or more amino acid residue differences of W106, Y72, T29, P286, T28, P26 and homologous sites thereof exist. When the ketene reductase disclosed by the invention is used for preparing (R)-4-propyl-dihydrofuran-2-ketone, the reaction time is relatively short, the conversion rate of a substrate is relatively high, and the ee value of (R)-4-propyl-dihydrofuran-2-ketone is relatively high, so that the ketene reductase is more efficient and suitable for industrial production.

The invention discloses ketene reductase and a method for preparing (R)-4-propyl-dihydrofuran-2-ketone by using the ketene reductase. Compared with an amino acid sequence as shown in SEQ ID NO: 1, an amino acid sequence of the ketene reductase has at least 95%, 96%, 97%, 98% or 99% of identity; and at least any one or more of differences of amino acid residues I67, C25 and Y27 and homologous sites thereof exist. According to the method, 5-hydroxy-4-n-propyl-2 (5H)-furanone is used as a substrate, the ketene reductase is used for enzyme catalysis to prepare the product (R)-4-propyl-dihydrofuran-2-ketone, the substrate is wide in source and low in price, hydroxyl does not need to be removed in advance in the catalytic reaction, one-pot reaction can be achieved, the total reaction time is short, and the synthesis efficiency of the product is high.

The application discloses a high-performance water-based acrylate floor latex emulsion and a preparation method and application thereof. The emulsion is prepared from raw materials containing the following components in parts by weight: 150-250 parts of soft monomers, 150-200 parts of hard monomers, 5-15 parts of functional monomers, 1-5 parts of crosslinking monomers, 10-40 parts of cyclic alkenyl ketone monomers, 6-11 parts of emulsifiers, 5-7 parts of pH buffers, 7-15 parts of initiators and 0.1-1.0 parts of catalysts. The water-based emulsion provided by the application has excellent bonding performance, strong peeling force, no drumming and no edge lifting after lamination, and can meet the demand of high-end floor glue paving industry.

This invention provides a method for synthesizing milobalin benzylsulfonic acid, comprising the following steps: a chiral enone undergoes a condensation reaction with cyanoacetate in the presence of ammonium acetate to obtain an unsaturated cyano ester; next, the unsaturated cyano ester undergoes a condensation reaction with nitromethane to obtain a nitro ester; the nitro ester is then deesterified at high temperature to obtain a chiral nitro nitrile, which is then reduced to a chiral amino nitrile; subsequently, the chiral amino nitrile is hydrolyzed to obtain the free base of milobalin; finally, the free base of milobalin is salted with benzylsulfonic acid to obtain milobalin benzylsulfonic acid. This invention stereospecifically constructs a chiral cyclobutane quaternary carbon center to obtain a chiral nitro ester with a single stereoconfiguration, avoiding the chiral isomer waste generated by chiral isomer resolution, eliminating the need for chiral column separation or chiral resolution, significantly reducing production costs, and simultaneously avoiding the environmental pollution caused by residual heavy metal titanium in the product and solid waste heavy metal titanium.

The present disclosure provides engineered enone reductase enzymes (EREDs), polypeptides having ERED activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing ERED enzymes are also provided. The present disclosure also provides engineered ketoreductase enzymes (KREDs), polypeptides having KRED activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing KRED enzymes are also provided. The present disclosure further provides compositions comprising the ERED and KRED enzymes and methods of using the engineered ERED and KRED enzymes. The present disclosure finds particular use in the production of pharmaceutical compounds.

Disclosed is a photosensitive resin composition comprising 20 to 60 parts by mass of an olefinic compound monomer, 20 to 60 parts by mass of an acrylate-based prepolymer, and 1 to 5 parts by mass of a photopolymerization initiator, the acrylate-based prepolymer comprising a rigid prepolymer having a functionality of 3 to 5 and a flexible prepolymer having a functionality of 2, the rigid prepolymer with the functionality of 3-5 and the flexible prepolymer with the functionality of 2 comprise one or a combination of more of epoxy acrylate, urethane acrylate and polyester acrylate, and the mass ratio of the rigid prepolymer with the functionality of 3-5 to the flexible prepolymer with the functionality of 2 is 0: 1-0.8: 1; the photopolymerization initiator comprises an oxime ester compound and a ketene compound, and finally the photosensitive resin composition which is wide in spectral response, high in curing speed and low in curing shrinkage rate and improves the curing depth regulation and control precision, the elongation at break and the tensile strength is obtained.