The invention provides wine cubes and belongs to the field of food processing. The wine cubes are formed mainly by sticky rice, oriental stephania roots, lalang grass rhizomes, areca nuts, herbs of pilose gerbera, herbs of ceylon leucas, ardisia crenata sims, Illicium simonsii, crneate lespedeza, licorice, radix asparagi, chrysanthemums, ginseng, the piper wallichii, longhairy antenoron herbs, Christina loosestrife, kudzu vines, licorice roots, paris polyphylla and red wheat. The invention further discloses a preparation method of the wine cubes. The piper wallichii has the good effects of strengthening yang and tonifying yin, dispelling wind and removing obstruction in the meridians, expelling wind-damp and treating waist-leg weakness, then the oriental stephania roots, the lalang grass rhizomes, the areca nuts, the herbs of pilose gerbera, the herbs of ceylon leucas, the ardisia crenata sims, the Illicium simonsii, the crneate lespedeza, the licorice, the radix asparagi, the chrysanthemums, the ginseng, the piper wallichii, the longhairy antenoron herbs, the Christina loosestrife, the kudzu vines, the licorice roots, the paris polyphylla and the red wheat are added, and in this way, the prepared wine cubes are rich in nutrient and free of toxic and side effects by the adoption of the pure natural raw materials.