36 results about "Molecular logic gate" patented technology

The invention discloses a molecular logic gate construction method based on interaction between cyanine dyes and metal ions. The method comprises the following steps: taking a cyanine dye solution as a template; taking Tris-HCl buffer solutions with different pH values and metal ion solutions as two parallel input signals, and taking the normalized result of absorbance of cyanine dye H-aggregates between 510 nm-520 nm or absorbance of J-aggregates between 650 nm-665 nm as output signals; setting a threshold value to be 0.03-0.3; and when the normalized result is larger than the threshold value, output being 1, and when the normalized result is smaller than the threshold value, output being 0, so that basic Boolean logic gates of an "OR" gate, a " NOR " gate and an "AND NOT " gate are constructed. The constructed molecular logic gates are good in circuit performance, high in sensitivity, large in switch ratio and easier to distinguish; the threshold value can reach 0.3; the output signals are easy to detect; and dependence on detection instruments is small, and detection can be realized through an absorption spectrometer.

The development of the first solution-phase molecular assembly comprising over 100 molecular logic gates, which more than quadruples the complexity performed by any previous system. “MAYA-II” is a second generation molecular automaton capable of playing a complete game of tic-tac-toe against a human opponent, and encompasses 76 permissible game plays. MAYA-II is more user-friendly than MAYA-I, as it signals both players move in a two-color output system and imposes no constraints on the position of the human player's first move. MAYA-II is constructed from three classes of stem-loop controlled deoxyribozyme-based logic gates that are allosterically modulated by input oligonucleotides to produce fluorescent output signals.

The present invention proposes a four-input factorial addition molecular circuit design method based on DNA chain replacement, the steps of which are: write out the factorials corresponding to two binary numbers, and list ten kinds of factorial sums of two binary numbers according to random combinations The truth table of the factorial addition operation circuit is constructed; the four-input factorial addition operation circuit is transformed into a dual-track logic circuit containing only logical AND gates and logical OR gates by adopting the dual-track idea, and DNA molecular logic gates are designed by using DNA molecules and four-input factorial is constructed. For the molecular circuit of addition operation, the correctness of the output results is verified by Visual DSD simulation software, the complex dynamic behavior of the four-input factorial addition operation molecular circuit is analyzed, and its dynamic behavior is verified. The invention provides a basic theoretical basis for constructing more complex logical operation circuits in the future, promotes the development of biological computers, and thus improves the reliability of biological computer logic circuits.

The invention discloses a pH fluorescence sensor based on a cadmium-containing coordination compound, and a preparation method thereof, and belongs to the field of chemical technology. The chemical formula of the cadmium-containing coordination compound is [Cd(2,4'-tmbpt)<2>(5-OH-bdc)]*5H<2>O. The preparation method comprises following steps: a mixture of Cd(CH<3>COO)<2>*2H<2>O, 5-hydroxy-isophthalic acid, 2,4'-tmbpt,NaOH, and water is sealed and heated in a reaction still provided with a polytetrafluoroethylene lining; after reaction, the temperature in the reaction still is reduced to room temperature at a cooling speed of 10 DEG C / h so as to obtain a colorless crystal which is the pH fluorescence sensor based on the cadmium-containing coordination compound. According to the preparation method, pH fluorescence sensing performance of the cadmium-containing coordination compound, and application research of the cadmium-containing coordination compound in the field of molecular logic gate are disclosed for the first time; repeatability is high; yield is high; product performance is stable; sensitive pH sensing properties are achieved; it is convenient to observe the change of fluorescence intensity; and molecular logic gates with INH functions can be obtained via design.