The invention discloses a spray for treating rheumatalgia. The spray is prepared by raw materials, namely, Oleum terebinthinae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Radix Saposhnikoviae, Radix Angelicae Pubescentis, Notopterygium incisum, Viscum album, Sanguis Draconis, Radix Angelicae Dahuricae, Asarum sieboldii, Carica Papaya, borneol, camphor, Artemisia lactiflora Wallex DC, Herba Abri, Leaf of argyi wormwood, Cortex Cinnamomi Cassiae, Pericarpium Zanthoxyli, Radix Achyranthis Bidentatae, Harms Manyprickle Acanthopanax, Caulis Piperis Kadsurae, Bungarus Parvus, Zaocys dhumnades, Semen Brassicae, Fructus Evodiae, rhizoma atractylodis, Milkvetch Root and Rhizoma Atractylodis Macrocephatae, which are all mixed in the proportion 1 : 1 and then brewed in yellow wine 1-10 times quantity of the total mixed drugs or sorghum liquor with more then 60 degrees for ten days. The invention has the efficacies of expelling rheumatism, dispelling cold-evil, promoting blood circulation by removing blood stasis, removing swelling and relieving pain, nourishing the stomach and invigorating the spleen, reinforcing the kidney and strengthening the bones, dredging meridians and collaterals and freeing channels, supplementing qi and nourishing blood, recovering and nourishing yin and strengthening antiviral ability and immunity of the human body.