The invention belongs to the technical field of packaging equipment, and particularly relates to a vacuum sealing machine. The vacuum sealing machine comprises a shell and a sealing cover connected tothe shell and capable of turning over relative to the shell, wherein a processing space allowing a packaging bag to stretch in is defined between the shell and the sealing cover, an exhaust assemblyis arranged in the shell, and an exhaust pipe capable of extending out of the shell and entering the processing space is arranged in the exhaust assembly; and a heating strip is arranged on the position, in the processing space, of the shell, a lower sealing strip is arranged on the position, in the processing space, of the shell, the lower sealing strip is located at the front end of the heatingstrip, the exhaust pipe passes through the upper end of the lower sealing strip when extending out of the shell, and an upper sealing strip aligned with the lower sealing strip is arranged on the position, in the processing space, of the lower end of the sealing cover. The vacuum sealing machine can carry out vacuum sealing treatment on any packaging bag.