The invention discloses a polyimide composite material-fluororubber material combined seal which is composed of a metal outer framework (1), a metal inner framework (2), a metal framework pressing ring (3), a fluororubber sealing ring (4), a carbon steel spring (5), a polyimide sealing ring (6) and a spring piece (7). The sealing device is mainly characterized in that the fluororubber sealing ring (4) and the carbon steel spring (5) are combined to seal oil, the carbon steel spring (5) provides corresponding holding force for the fluororubber sealing ring (4), the polyimide sealing ring (6) is made through a machining process and combined with the spring piece (7) to seal gas, and the spring piece (7) improves the following performance of the polyimide sealing ring (6). Through the combination of different materials and different structure seals, a sealing product can seal grease and high-pressure air at the same time, and the sealing performance is maintained at a reasonable level for a long time. The sealing device is stable in working condition, reliable in sealing performance, long in service life, convenient to install, good in universality and interchangeability, capable of adapting to working conditions of high temperature, high speed, dry grinding and the like, and particularly suitable for the severe environment where a sealing shaft jumps randomly and other conditions with the harsh sealing requirement.