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43results about How to "Reduce Optical Interference" patented technology

Method and apparatus for detection of vulnerable atherosclerotic plaque

Methods for the detection of inflammation associated with vulnerable atherosclerotic plaque to prevent heart attack and stroke are disclosed. The methods are also applicable to detection of infection, cancer, wounds or auto-immune disease in the body. Certain embodiments of the new methods provide a way of predicting the level of vulnerability of an atherosclerotic plaque to rupture or thrombus formation by assessing via fiber optic NIR spectrophotometry the status of two or more parameters associated with inflamed atherosclerotic plaque in a vessel of a living patient. From these measurements such conditions as low pH, hypoxia, low glucose, oxidative stress or compounds abundant in vulnerable plaque such as oxidized LDL cholesterol and oxidized metabolites of NO, significant active macrophage population, thin plaque cap, as well as senescence and/or apoptosis of smooth muscle or endothelial cells are determined with the assistance of a suitably programmed microprocessor. By considering together the status of some or all of these conditions with respect to successive sites along a vessel wall, particular plaques which are at significant risk of rupturing or thrombosing can be distinguished from “normal” vessel wall and from “intermediate” and relatively stable or “lower risk” plaques. Sites having more of the indicator conditions would be considered most in need of prompt intervention, and certain combinations of parameter levels would be suggestive of relatively stable plaque.
Also disclosed is a multi-parameter catheter and analytical processing assembly for use in the methods.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

ph fluorescent sensing film and method for detecting ph two-dimensional dynamic distribution of basic sediment

The invention discloses a pH fluorescent sensing film which comprises a film base material and is characterized in that fluorescent dyes of CPIPA (Chloro Phenyl Imino Propenyl Aniline) and fluorandiol 10-GN are uniformly mixed together, and the two fluorescent dyes are fixed on the surface of the film base material by virtue of a chemical embedding method. On the basis of the pH fluorescent sensing film, the invention also discloses a method for detecting pH two-dimensional dynamic distribution of basic sediment, wherein the pH fluorescent sensing film is put into the sediment, spectral information of the two dyes is obtained by virtue of an imaging device under the illumination of exciting light, and distributional characteristics of the pH of the sediment are obtained by virtue of R and B passage fluorescent ratio quantification. According to the sensing film disclosed by the invention, the CPIPA and the fluorandiol 10-GN which has a reference effect and a brightening effect are mixed together to form a fluorescent indicator, and the sensing film has high detection sensitivity and high spatial resolution and is sensitive to respond pH changes. The method adopts a plate electrode technology to realize real-time and in-situ acquisition of pH two-dimensional and dynamic distribution information of the basic sediment by reducing optical interference by virtue of fluorescent ratio quantification.
Owner:NANJING INST OF GEOGRAPHY & LIMNOLOGY

X-ray sensor and manufacturing method thereof

The invention relates to an X-ray sensor and a manufacturing method thereof. The X-ray sensor comprises a sensing substrate and a lead glass substrate, wherein the sensing substrate is provided with a plurality of sensing units; the lead glass substrate comprises a first surface and a second surface which are opposite; the first surface is fixed on the sensing substrate and a plurality of grooves which correspond to the plurality of sensing units one by one are formed in the second surface; the lead glass substrate also comprises a first reflecting layer, scintillator fluorescent powder and a second reflecting layer; the first reflecting layer is arranged on the side walls of the plurality of grooves; the plurality of grooves are filled with the scintillator fluorescent powder; and the second reflecting layer is arranged on the second surface. According to the X-ray sensor provided by the invention, the damage of an X ray to the plurality of sensing units can be effectively blocked through a method of adding lead glass between the scintillator fluorescent powder and the plurality of sensing units; and furthermore, the lead glass has relatively high penetration rate and a high refractive index, so that optical interference caused by light scattering can also be effectively reduced.
Owner:AU OPTRONICS KUNSHAN CO LTD +1

Photo-Electric Conversion Element Array, Integrated Apparatus Of The Same, Mounted Structures Of Them, And Optical Information Processing Apparatus

A photoelectric conversion element array having a plurality of photoelectric conversion elements (emitting optics 4, receiving optics 5) arranged in an array, and the photoelectric conversion elements 4, 5 are arranged alternately at different positions so that every second one is aligned on the same line in the direction of array. A mounted structure of photoelectric conversion element array, having the emitting optics array and the receiving optics array in the photoelectric conversion element array of this invention, arranged on an interposer substrate 9 so as to oppose therewith, and these arrays are mounted on the interposer substrate 9 through the external connection terminals 7. An optical information processing apparatus 1 having the photoelectric conversion element array of the present invention, and an optical wave guide 3 opposed to the respective optics of the photoelectric conversion element arrays. These configurations not only allow high-density integration of optical interconnects, but also reduce optical interference or crosstalk due to the photoelectric conversion element, and can thereby provide a photoelectric conversion element array allowing efficient propagation of light, an integrated apparatus thereof, a mounted structure of them, and an optical information processing apparatus.
Owner:SONY CORP

Photo-electric conversion apparatus with alternating photoelectric conversion elements

A photoelectric conversion element array having a plurality of photoelectric conversion elements (emitting optics 4, receiving optics 5) arranged in an array, and the photoelectric conversion elements 4, 5 are arranged alternately at different positions so that every second one is aligned on the same line in the direction of array. A mounted structure of photoelectric conversion element array, having the emitting optics array and the receiving optics array in the photoelectric conversion element array of this invention, arranged on an interposer substrate 9 so as to oppose therewith, and these arrays are mounted on the interposer substrate 9 through the external connection terminals 7. An optical information processing apparatus 1 having the photoelectric conversion element array of the present invention, and an optical wave guide 3 opposed to the respective optics of the photoelectric conversion element arrays. These configurations not only allow high-density integration of optical interconnects, but also reduce optical interference or crosstalk due to the photoelectric conversion element, and can thereby provide a photoelectric conversion element array allowing efficient propagation of light, an integrated apparatus thereof, a mounted structure of them, and an optical information processing apparatus.
Owner:SONY CORP
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