211results about How to "Release completely" patented technology

The invention discloses a depressurized extraction method for cutting through a roof or a floor of a coal seam by an abrasive water jet, which comprises the following steps: a. drilling a bedding drill hole to set depth on the roof or the floor of a coal-rock mass or a hard layer by using a drilling machine through a drill stem and a slotting drill bit; b. delivering a high-pressure abrasive water jet of which the pressure is 25-30MPa to the slotting drill bit through the drill stem, wherein the drill stem rotates in situ; forming a radial slit on the hole wall of the bedding drill hole, wherein the slit penetrates the roof or the floor of the coal-rock mass or the hard layer and a soft layer; c. enabling the drill stem to rapidly retreat for 1.5-3m so as to form a new slit; d. repeating the step c until a plurality of radial slits are formed on the bedding drill hole, and moreover, reserving a safety rock pillar of at least 5m at the slit located at the position of the orifice of the bedding drill hole at a certain distance from the orifice; e. retreating the drill stem and the slotting drill bit and sealing the hole; and f. extracting gas by a gas extraction system. The depressurized extraction method for cutting through the roof or the floor of the coal seam by the abrasive water jet has the beneficial effects that the drill hole does not have potential safety hazards and is easy to form; a hole sealing effect is good; the time of reaching the standards of extraction is short; the production efficiency is high; and the extraction is safe.

The present invention discloses a kind of slow releasing enteric soluble coated tablet containing hyperzine A and its preparation process. Enteric soluble coating technology is adopted to overcome the bad effect of lower pH in stomach on the diffusion of medicine in skeleton tablet to ensure the stable, slow and complete release of medicine. The slow releasing tablet contains hyperzine A as reversible anticholinesterase and has one layer of enteric soluble polymer film coating outside the skeleton slow releasing layer. The active medicine component may be also various pharmaceutically acceptable acid salts of hyperzine A. Each tablet contains hyperzine A I n10-500 microgram and has sustained release time of 20 hr.

The invention provides a preparation method of a sustained-release preparation containing felodipine. The invention is characterized in that the felodipine and bond are dissolved in ethanol absolute solution or water solution containing more than 60 percent ethanol, then are fixed with matrix sustained-release necessities and filling agent and finally are moistened and granulated by the ethanol absolute solution or the water solution of ethanol. The invention also provides the sustained-release preparation prepared by the method and usage in preparation of medicine for treating hypertension.

The invention discloses an edible condiment packing bag. The edible condiment packing bag comprises components in percentage by weight as follows: 55%-80% of starch, 5%-20% of algal polysaccharide, 8%-20% of plant fiber, 0.1%-10% of a reinforcing agent and 7%-12% of water. A preparation method of the edible condiment packing bag comprises the steps of burdening, glue solution preparation, glue cultivation, blank preparation, drying, shell forming through drawing and the like. The packing bag has the characteristic that the packing bag is easily dissolved in hot water and releases content and the flavor of food is not influenced after the packing bag is dissolved; the packing bag has better mechanical strength, can meet the requirement of packing bags for large-scale industrial automated filling, has good environment tolerance and content storage performance by the aid of humidity resistance, oil resistance and oxygen barrier performance, has good universality and wide application range, can be used for packing edible content such as solid, grease or dehydrated condiment, functional food, health care products and the like and has the advantages of convenience in use, no waste, no pollution to the content, environmental protection and the like.

The invention relates to technique for improving an electric heating element, in particular to nano far infrared negative ion carbon crystal conductive paper and a method for making the same. The conductive paper resolves the problems of the uneven heat generation, the existence of heat spot and the excessive temperature difference existing in prior electric heating products and is used for electric heating elements for anti-static electricity and making of heating electric hot plates. The conductive paper comprises the following components in percentage by weight: 70 to 96 percent of paper pulp, 2 to 20 percent of nano carbon fiber, 1 to 5 percent of nano far infrared negative ion powder and 1 to 5 percent of dispersing agent. In the invention, by using paper pulp, nano carbon fiber, nano far infrared negative ion powder and dispersing agent as materials and undergoing steps of pulping, pulp beating, pulp mixing, papermaking, drying and scrolling, etc., the conductive paper is made; in the process of pulp beating, the pulp mixing step is made; the pulp mixing step is as follows: nano carbon fiber and dispersing agent and nano far infrared negative ion powder are evenly added in the paper pulp. The invention possesses of functions of the emission of far infrared rays and the release of negative ions at the same time and can effectively and completely release electric charges, thereby having effects of purification and disinfection and making human bodies healthier.

The present invention relates to a ranolazine hydrochloride delayed-release preparation and its preparation method. Said ranolazine hydrochloride delayed-release preparation contains 25-95 wt% of ranolazine hydrochloride and one or several kind of medicinal inert auxiliary materials, including delayed-release matrix, adhesive, disintegrating agent, diluent, lubricating agent, flow aid or moistening agent.

The invention relates to a recombinant human Endostatin porous sustained-release microsphere for injection, and a preparation method thereof, in particular to an injection-use porous sustained-release microsphere which takes a biodegradable polymer of lactic acid and hydroxyacetic acid as a matrix and comprises recombinant human Endostatin and a pore-forming agent, and a preparation method thereof.

The invention relates to a cefuroxime axetil odor-masking pellet and a preparation method thereof. The cefuroxime axetil odor-masking pellet consists of an uncoated pellet containing the cefuroxime axetil and an odor-masking layer coating outside the uncoated pellet. The cefuroxime axetil odor-masking pellet overcomes the defect of bitter taste of the prior cefuroxime axetil tablets, and provides a novel cefuroxime axetil preparation which masks bitter taste, releases medicament rapidly and has stable quality.

The invention provides a compound preparation of pioglitazone hydrochloride and metformin hydrochloride bilayer osmotic pump controlled release tablets. The compound preparation structurally comprises the following parts from inside to outside in sequence: a tablet core comprising a drug layer and a digestive layer, an insulation coating layer, a controlled release coating film with drug release holes, a rapid pioglitazone hydrochloride release layer and an unnecessary attractive coating. The invention also provides a preparation method of the compound preparation of pioglitazone hydrochloride and metformin hydrochloride bilayer osmotic pump controlled release tablets. The preparation method comprises the following steps of: (1) preparing the drug layer; (2) preparing the digestive layer; (3) tabletting the tablet core; (4) coating insulation coating layer; (5) coating the controlled release coating; (6) punching the coated tablet: (7) coating the rapid pioglitazone hydrochloride release layer; and (8) coating the attractive coating.

The invention discloses a biological enzyme demulsification method for extracting soybean oil and fat by an aqueous enzymatic method and belongs to vegetable oil and fat extraction technologies. The method includes the following steps of (1) smashing puffed soybeans, mixing the smashed soybeans with water to obtain a mixed liquor, adding alkaline protease in the mixed liquor to perform an enzymolysis reaction, and after the enzymolysis, performing a centrifugal separation to obtain free oil, an emulsion, a hydrolysate and residues; (2) adding water and phospholipase in the emulsion obtained from the step (1) to stir to perform the enzymolysis reaction to obtain a reaction solution; and (3) adding alcohol in the reaction solution obtained from the step (2) to perform an ultrasonic processing, and then performing the centrifugal separation to obtain the soybean oil and fat. The biological enzyme demulsification method for extracting the soybean oil and fat by the aqueous enzymatic method has the advantages that the required processing equipment is simple, the demulsification time is short, the method is environment-friendly, and the demulsification rate is high.

The invention discloses a production process and a production device of a urea formaldehyde slow-release synergistic fertilizer. The process includes urea formaldehyde solution preparation, granulation, post-processing and other steps. The device includes a urea formaldehyde reaction tank; the urea formaldehyde reaction tank is connected with a buffer tank through a urea formaldehyde pump, and the buffer tank is successively connected with a granulator, a dryer, a cooler, a screening machine, a coating machine and a packaging machine. The production process and the production device have the advantages that the process material is high in ball forming rate, and the liquid phase is less, so that the drying load is relieved, the productivity is improved, and energy consumption is reduced; and the urea formaldehyde slow-release synergistic fertilizer obtained through the process can meet nutrient demands of crops at different growth periods with one time fertilization, has quick-acting, intermediate-acting and long-acting nitrogen nutrients, can achieve the purpose of sustained or controlled release, is complete in nutrients, high in fertilizer efficiency, obvious in yield increasing effect and stable and lasting in fertilizer efficiency, has a soil improving effect, and also has the advantages of low water content, high particle strength, green environmental protection, and no residue.

The invention discloses a low-carbon and low-NOx sintering method based on reasonable distribution of fuel. According to the low-carbon and low-NOx sintering method based on reasonable distribution offuel, a lower fuel layer is mainly fed with new fuel which is high in burning speed, relatively low in heat value and low in nitrogen content, an upper fuel layer is fed with fossil fuel which is lowin burning speed and high in heat value, flue gas with high in CO content in an intermediate air bellow of a sintering machine is circulated to a sintered material surface at the same time, and latent heat of the flue gas is fully utilized for further supplementing heat to the upper fuel layer. According to the low-carbon and low-NOx sintering method based on reasonable distribution of fuel, thecharacteristics that the sintering speed changes from low to high from the upper fuel layer to the lower fuel layer, and heat storage changes from low to high, the difference between the burning speedof the new fuel and the fossil fuel, and the difference between the heat value of the new fuel and the fossil fuel are effectively coupled, the CO latent heat in the fuel gas is efficiently utilized,and at the same time of increasing sintering yield and improving quality indexes, solid fuel consumption of each ton of sinter is reduced by 2kgce to 4 kgce, CO emission is reduced by 30% to 50%, NOxemission is reduced by 40% to 60%, and low-carbon and low-NOx sintering is implemented.

The invention provides a multicomponent sustained-release preparation and a preparation method thereof. An isolation layer is arranged between a sustained-release part and a quick release part in the sustained-release preparation to effectively isolate the interaction of a sustained-release tablet core and an external quick release coat, the external quick release part is quickly released completely, the isolation layer is quickly dissolved when meeting an aqueous medium, and the release of the sustained-release tablet core is not influenced. The technology can be applied to compound sustained-release preparations as required.

The invention provides a direct real-time quantitative fluorescent PCR method of a layered packaging tape indicator. Hot-start DNA polymerase and PCR amplification reaction liquid are both packaged in a PCR amplification tube in layers. Nucleic acid lysis liquid and a sample to be detected are added when the method is used so that real-time quantitative fluorescent PCR can be carried out. By means of the method, the virus quantity lower to 20IU/ml can be detected, and the preferential detection range is 30-2*10<9>IU/ml. Detection results are not limited by the professional level of operators and experiment conditions in a laboratory, and the method has the advantages of being easy, convenient and quick to operate.

The invention discloses a method for measuring the content of a hydrogen element in a nuclear-grade zirconium material. The method comprises the following steps: 1, cutting the nuclear-grade zirconium material into 0.1-0.3g of a solid test sample; 2, firstly, pickling the solid test sample for 5-30s so as to remove an oxygen enrichment layer on the surface of the solid test sample and hydrogen and other gas elements adsorbed in the machining process, subsequently washing the pickled test sample for 10-50 seconds by using acetone, subsequently putting the test sample into an oven to be dried at 50-60 DEG C, and removing a contaminated layer on the surface of the test sample so as to ensure the cleanness of the test sample; 3, putting the test sample pretreated in the step 2 into a hydrogen measuring instrument so as to measure the content of the hydrogen in the solid test sample by using the hydrogen measuring instrument. By adopting the method, the defects of the conventional measuring method are overcome, and requirements of practical detection on the nuclear-grade zirconium material are met.

The invention relates to the field of a drug preparation, in particular to a hydrochloric acid bupropion slow release micro pill and a method for preparing the same. The micro pill consists of a drug containing pill core and a slow release coating layer which consists of slow release materials and a pore-forming agent, wherein the weight of the slow release materials against the weight of the drug containing pill core is between 8 and 15 percent, and the weight of the pore-forming agent against the weight of the slow release materials is between 1 and 6 percent. The micro pill does not need to be combined by a plurality of micro pills with different release modes, and only adopts a single micro pill to achieve the good release performance, thereby lowering production cost and simplifying production process.

The invention provides an exosome-compounded collagen biological scaffold with a directional releasing function as well as a preparation method and application thereof. The exosome-compounded collagenbiological scaffold comprises nano collagen and exosomes dispersed in the nano-collagen. The preparation method of the biological scaffold comprises the following steps: separating collagen from animal tissue, carrying out ball milling till the collagen is nanoscale collagen; separating exosomes from culture of bone marrow or umbilical cord mesenchymal stem cells; mixing the exosomes with the collagen, freezing and drying. The preparation method of the biological scaffold is used for dispersing the exosomes in the nanoscale collagen to form a biological scaffold material with a function of directionally releasing exosomes; the targeted repairing and treating effects of the exosomes can be obviously improved; the development tendency of accurate drug administration can be met; the dosage forms are various; the biological scaffold has extensive clinical application values.

The invention relates to a rosuvastatin calcium oral solid preparation and applications thereof. The rosuvastatin calcium oral solid preparation is prepared in tablets and capsules by a solid dispersion technology so as to increase the stability of the preparation, simultaneously enable the medicine to be released slowly and continuously and further effectively avoid the adverse effect caused by peak-valley fluctuation of the blood concentration.