The invention relates to a boost phase generalized standard miss distance analysis guidance method. The method comprises steps that 1, boost phase guidance problem modeling is carried out, including standard ballistic movement modeling, guidance correction first-order perturbation modeling and terminal constraint modeling; 2, boost phase standard ballistic regular perturbation solution modeling is carried out; 3, boost phase standard ballistic zero-order item analysis solution on the basis of regular perturbation is carried out; 4, boost phase standard ballistic first-order item analysis solution on the basis of regular perturbation is carried out; and 5, boost phase optimal guidance instruction solution on the basis of the standard miss distance is carried out. Through the method, zero-incidence is taken as boost phase ballistic standard control, analysis solution is carried out by employing a regular perturbation method, and thereby an analyzed standard miss distance is acquired; an optimal control method is employed to solve a guidance instruction of the correction standard miss distance, and thereby a non-linear analysis optimal guidance method satisfying boost phase task demands is acquired.