The invention relates to a thioxanthone photo-initiation group modified hyperbranched LED resin and a preparation method thereof, wherein the thioxanthone photo-initiation group modified hyperbranched LED resin takes TMP as a core and a hyperbranched unit as a shell, and contains a plurality of functional active groups, a plurality of thioxanthone photo-initiation groups and a plurality of branched chain bulk alkane groups. The thioxanthone photo-initiation group modified hyperbranched LED resin has the characteristics that 1) energy migration and intermolecular reaction in a polymer chain are easier, and the self-initiation efficiency is high; 2) the distance between a photoactive group and a main chain is shortened, and the photosensitivity is improved; 3) the system compatibility is excellent; 4) the thioxanthone photo-initiation group modified hyperbranched LED resin has characteristics of high solid content, low viscosity, pigment bearing performance and storage stability; and 5) the defects caused by a small-molecule photoinitiator are overcome. The hyperbranched LED resin prepared by the invention has excellent flexibility, adhesive force, chemical resistance, heat resistance, aging resistance, oil resistance, wear resistance, pollution resistance and impact strength, is odorless in coating, and is used for LED colored floor coating materials, LED woodware coating materials, LED alloy coating materials, LED circuit board ink and LED plastic coating materials.