The invention discloses a punching device of a cosmetic bottle. The punching device comprises guide wheels, a level gauge, a box body, supporting legs, a mounting platform, a heat dissipation fan, a camera, noise reduction blocks, LED (Light Emitting Diode) lamps, noise reduction holes, retractable rods, a punching machine, fixing clamps and a dust collector, wherein the guide wheels are arranged on the bottom surface of the box body and the supporting legs are arranged in the box body; the mounting platform is arranged at the tops of the supporting legs; a slide rail is arranged on the mounting platform; the fixing clamps are arranged in the slide rail and the heat dissipation fan is arranged on one side of the mounting platform; a timer is arranged on an outer wall of the box body; vent holes are formed in a side wall of the box body; the camera is arranged on the mounting platform; the retractable rods are arranged on an inner wall of the top of the box body; the punching machine is arranged at the bottom ends of the retractable rods; the LED lamps are arranged on the inner wall of the top of the box body; the noise reduction blocks are arranged on the inner wall of the box body; the noise reduction holes are formed in the noise reduction blocks; and the box boxy is internally provided with the dust collector. With the adoption of the punching device of the cosmetic bottle, injuries on eardrums and body health of workers are reduced, and power generated by punching is collected in time, so that the body health of people are not influenced; and the punching device of the cosmetic bottle is simple in structure, convenient to use and good for popularization.