43 results about "Spherical cell" patented technology

Provided are: a polishing pad, which improves the problem of scratches that are produced in cases where conventional hard (dry) polishing pads are used, which has having excellent polishing rate and polishing uniformity, and which is applicable not only to primary polishing but also to final polishing; and a method for producing the polishing pad. A polishing pad for semiconductor device polishing, which comprises a polishing layer having a polyurethane polyurea resin molded body that contains generally spherical cells. This polishing pad for semiconductor device polishing is characterized in that: the polyurethane polyurea resin molded body has a closed cell ratio of 60-98%; the ratio of the loss modulus (E") to the storage modulus (E'), namely loss modulus/storage modulus (tan delta) of the polyurethane polyurea resin molded body is 0.15-0.30; the storage modulus (E') is 1-100 MPa; and the polyurethane polyurea resin molded body has a density (D) of 0.4-0.8 g/cm<3>.

The invention relates to a method for growing cell embryos of Dendrobium huoshanense, which comprises the following operating steps: (1) inducing sterile in-vitro cuttings; (2) inducing embryonic calli; (3) inducing somatic embryos; and (4) performing synchronous propagation of somatic embryos to obtain a large amount of cell embryos of Dendrobium huoshanense. In the method, morphological lower ends of the jointed stem segments of the sterile in-vitro cuttings are used as explants, the oxidation-reduction potential of the induction culture medium is controlled, exogenous hormone is not required to be added to induce the embryonic calli of Dendrobium huoshanensem, and the exogenous hormone is prevented from being enriched into complete plants through somatic cells and endangering health of human body. By controlling ambient humidity, embryonic calla are grown into somatic embryos, the consistency of spherical cell embryos is over 90 percent, and the survival rate of regenerated plants is over 85 percent. In the invention, the process is simple and not limited by time and seasons, and industrial automatic production of g cell embryos of Dendrobium huoshanense and in-vitro cuttings of Dendrobium huoshanense can be carried out in door for satisfying needs for production and planting.

Provided are a novel foam which has a uniform fine-cell structure and is excellent in toughness and heat resistance, and a production method therefor. Also provided is a functional foam which includes the above-mentioned foam and has imparted thereto various functions. The foam includes spherical cells, in which: the spherical cells each have an average pore diameter of less than 20 μm; the foam has a density of 0.15 g/cm³ to 0.9 g/cm³; and the foam is crack-free in a 180° bending test. The functional foam includes the foam.

Provided is a novel composite sheet, including a substrate and a foamed layer which is provided on at least one surface side of the substrate, at a low cost in an environment-friendly manner, in which the composite sheet includes a foamed layer having a uniform fine-cell structure, the average pore diameter of each of spherical cells of the foamed layer can be precisely controlled to a small one, the control range of the density of the foamed layer is wide, the control range of the thickness of the foamed layer is wide, and the composite sheet can express an excellent mechanical strength and is preferably excellent in toughness and heat resistance. The composite sheet includes a substrate; and a foamed layer which is provided on at least one surface side of the substrate, in which: the foamed layer has spherical cells, an average pore diameter of each of the spherical cells being less than 30 μm; and the foamed layer has a density of 0.1 g/cm³ to 0.9 g/cm³.

In a cylinder block, at least one member disposed around a bore is made of a metal matrix composite including a ceramic compact having a three-dimensional mesh structure comprised of a plurality of spherical cells and a plurality of communicating pores for allowing adjacent spherical cells to communicate with each other, with the plurality of spherical cells filled with a metal.

A polishing pad for polishing a semiconductor device and manufacturing method therefor, the polishing pad comprising a polishing layer having a polyurethane-polyurea resin foam containing substantially spherical cells, wherein an M-component of the polyurethane-polyurea resin foam has a spin-spin relaxation time T2 of 160 to 260 μs, the polyurethane-polyurea resin foam has a storage elastic modulus E′ of 1 to 30 MPa, the storage elastic modulus E′ being measured at 40° C. with an initial load of 10 g, a strain range of 0.01 to 4%, and a measuring frequency of 0.2 Hz in a tensile mode, and the polyurethane-polyurea resin foam has a density D in a range from 0.30 to 0.60 g/cm³. The polishing pad remedies the problem of scratches occurring when a conventional hard (dry) polishing pad is used, which is excellent in polishing rate and polishing uniformity, and can be used for primary polishing or finish polishing.

Provided are a polishing pad which remedies the problem of scratches occurring when a conventional hard (dry) polishing pad is used, which is excellent in polishing rate and polishing uniformity, and which can be used for not only primary polishing but also finish polishing, and a manufacturing method therefor. The polishing pad is a polishing pad for polishing a semiconductor device, comprising a polishing layer having a polyurethane-polyurea resin foam containing substantially spherical cells, wherein the polyurethane-polyurea resin foam has a hard segment content (HSC) in a range from 26 to 34%, and has a density D in a range from 0.30 to 0.60 g/cm³, the hard segment content (HSC) being determined by the following formula (1):

HSC=100×(r−1)×(Mdi+Mda)÷(Mg+r×Mdi+(r−1)×Mda)  (1).

A process for producing a ceramic molding having a three-dimensional network structure with a plurality of spherical cells and a plurality of through holes present in dividing walls between the spherical cells, includes: a step of obtaining an aggregate of coated particles in which a plurality of ceramic particles are attached to the surface of spherical synthetic resin particles; a step of arranging the aggregate of coated particles in closest packed form within a mold; a step of filling gaps in the aggregate of coated particles with a ceramic so as to give a shaped product; a step of releasing the shaped product from the mold; a step of thermally decomposing the spherical synthetic resin particles of the shaped product so as to form the spherical cells and form the plurality of through holes in dividing wall-forming sections that are present between adjacent spherical cells; and a step of sintering the ceramic particles and the ceramic so as to form the dividing walls.

The invention relates to a microsphere with multiple magnetic nano cores@gaps@porous shell structures and a preparation method thereof. The microsphere structure is characterized in that a porous hollow shell contains a plurality of magnetic nano cores. In the preparation method, iron (III) is taken as the single iron precursor, the spherical cell wall of unicellular algae is taken as the precursor of porous microsphere wall, the substances in the algae cells are used to replace chemical reagents to carry out reactions, and a hydrothermal method with mild conditions is performed to prepare the microsphere with multiple magnetic nano cores@gaps@porous shell structures. The preparation method is simple; a microsphere, which has a complicated structure composed of a porous hollow shell and a plurality of magnetic cores, can be produced without a template; the preparation process is green and environment-friendly; no organic reagent is added, and the obtained microsphere has the advantages of excellent magnet-response performance and large loading space.

The invention discloses a 3D microcavity impedance sensor for real-time monitoring of activity and proliferation ability of cells and preparation method. The 3D microcavity impedance sensor is firstlymanufactured by adopting a micro-nano processing technology; 3D spherical cell culture is conducted on tumor cells; 3D spherical cells are inoculated into a trapezoidal microgroove structure in the microcavity impedance sensor, are attached to counter electrodes on the side wall of the microgroove and cause the reduction of the transfer efficiency of electrons on the electrode surfaces, so that the impedance values of the electrodes rise and are increased with diameter increase of proliferation spheres of the 3D spherical cell, and after an anti-tumor drug acts on the 3D spherical cells to cause apoptosis, the impedance values of the electrodes are decreased, and the activity and proliferation ability of the 3D spherical cells are monitored by calculating the change rate of the impedancevalues of the 3D spherical cells. The constructed microcavity impedance sensor can monitor the activity and proliferation ability of 3D spherical cells with high throughput in real time for a long time.

The invention discloses a culture method of AD293 spherical cell cluster. The culture method comprises the following steps: (1) preparing a suspension culture medium: preparing the following components: a serum-free culture medium, fetal calf serum, a serum replacement, a non-essential amino acid solution, epidermal growth factor, transforming growth factor, and methyl cellulose, and evenly mixing and dissolving the components mentioned above to obtain a suspension culture medium; (2) preparing AD293 cells: using a DMEM culture medium with 10% of fetal calf serum to revive AD293 cells in a cell culture flask, and carrying out cell passage; (3) culturing the cells: adding AD293 cells obtained in the step (2) and suspension culture medium obtained in the step (1) into a shake flask, then placing the shake flask on a shaking bed, and culturing the cells for 48 to 72 hours at a temperature of 37 DEG C to obtain AD293 spherical cell clusters. Compared with the cells cultured by spherical suspension micro carriers, the cell density of obtained AD293 cell clusters is increased by 10 times or more.

The invention relates to a preparation method of a double-layer cell ball. The invention aims at providing a preparation method of the double-layer cell ball, comprehensively and truly reflecting the survival environment of in-vivo cells, and visually reproducing the interaction between two kinds of cells under certain conditions. The technical schemes for achieving the aims are as follows: the preparation method of the double-layer cell ball comprises the steps of: a. separately culturing two different kinds of cells; b. preparing a single cell suspension from one kind of the cells; c. controlling the single cell concentration in a bottle at 1*10<5>-1*10<6> cells/ml; d. standing the single cell suspension in a 37 DEG C incubator containing 5% of CO2 for 1-4 hours; e. carrying out rotation culture on the single cell suspension for rolling the single cell suspension into balls, and changing the single cell suspension once every 10-14 hours; and f. preparing a single cell suspension of the other kind of cells, and adding the single cell suspension to the culture liquid containing the cell balls obtained in step e, continuing rotation culture so that the two kinds of cells in a tube form a spherical cell mass with a clear boundary and a double-layer structure, and changing the suspension once every 10-14 hours. The preparation method of the double-layer cell ball provided by the invention is mainly used for three-dimensional culture of cells.