The invention provides a dendrobium nobile mooncake and a making method thereof, and relates to the technical field of food. The dendrobium nobile mooncake comprises the following components: weak strength flour, syrup, edible oil, dendrobium nobile juice, dendrobium nobile powder, pericarpium citri reticulatae, tea leaves, alkaline water, shelled melon seeds, sesame, walnuts, cashew kernels, almonds, peanut kernels, preserved fruits, white gourd sugar, glutinous rice flour, dendrobium nobile wine, soy sauce, edible salt, white sugar, honey, scallions, pepper powder, barbecued pork, dried meat floss, eggs and water. The dendrobium nobile mooncake is oily but not greasy, has a rich aroma, endless aftertaste, high nutritional value, and good health care effect. In addition, the invention further provides the making method of the dendrobium nobile mooncake, and the making method comprises the following steps of cake crust material preparation, cake filling material preparation, dendrobium nobile mooncake making and finished product packaging. The method is simple in process, and the made dendrobium nobile mooncake is complete in color, aroma and taste, capable of promoting appetite, high in nutritive value and good in health care effect.