The invention relates to the field of wastewater treatment, and particularly relates to a disposal method of pyrolysis comprehensive wastewater of solid waste. The disposal method comprises the following steps of first carrying out oil separation and precipitation treatment, gas-liquid blowing off treatment, advanced oxidation treatment and coagulation and precipitation treatment on high-pollutant-concentration pyrolysis condensation water which contains many aromatic compounds in sequence then mixing the high-pollutant-concentration pyrolysis condensation water with oven-drying and squeezing water, fume treatment wastewater, sanitary sewage and ground flushing water, which are subjected to primary precipitation treatment, finally, carrying out anaerobic treatment, facultative aerobic treatment, aerobic treatment, secondary precipitation treatment, the advanced oxidation treatment and secondary coagulation and precipitation treatment on formed comprehensive wastewater in sequence, and making the comprehensive wastewater meet a discharge requirement. By using the disposal method of the pyrolysis comprehensive wastewater of the solid waste, which is provided by the invention, the investment cost and the running cost of the wastewater can be effectively decreased; meanwhile, the integral shock-resistance ability is improved; moreover, the disposal method comprises multiple technical chains; requirements on yielding water of different grades and different standards can be met; the applicability is higher.