The invention discloses a toy packaging bag sealing machine which structurally comprises supporting base rods, universal wheels, a maintenance cover plates, a power machine base, an assembly connection plate, a sealing base plate, a sealing machine table, a control panel, a lifting pump rod, a heat sealing transmission line plate and a heat sealing plate. The power machine base is in a cuboid shape, the maintenance cover plates are connected to the front and rear ends and the left and right ends of the power machine base in an embedded fastened mode, the supporting base rods and the universalwheels are perpendicularly locked and connected to the four corners at the bottom end, the assembly connection plate is in a cuboid shape, horizontally locked and connected to the middle of the frontand rear sides of the top end of the power machine base, and electrically connected with the power machine base, the sealing machine table is perpendicularly locked and connected to the left side of the top end and electrically connected with the sealing machine table, the sealing base plate is fastened and connected to the right side of the top end, the sealing machine table is in an inverted L shape, and the short edge is located on the upper side of the right end. When a user uses the toy packaging bag sealing machine, by means of a wire winding and lifting mechanism composed of wires, gears, springs, clamping rods and the like arranged on the equipment, separated installation of a power table and the machine table is achieved, placing safety and stability of machine table are ensured during separated installation of the equipment, and use is more convenient.