The invention discloses an air energy jet flow micro inflow type cosmetic instrument. The instrument comprises a mesogun shell, an injector, a key switch, a control cabinet, a driving mechanism installed on the mesogun shell and a liquid medicine injection mechanism. The control cabinet comprises an equipment cabinet, and an air compressor and a controller which are arranged inside the equipment cabinet; the driving mechanism comprises a gear motor, a lead screw, a nut, a nut connecting block, a push block and a baffle, the nut connecting block is connected with the nut through a peripheral positioning column, the push block is detachably connected with the nut connecting block through a clamping hook, an injector abutting portion is arranged at the upper portion of the push block, a liquid medicine outlet of the injector is connected with the liquid medicine injection mechanism, and compressed air of the air compressor is connected with the power input end of the liquid medicine injection mechanism. The compressed air is used for pushing the liquid medicine for high-speed motion to form spray steam, liquid medicine permeates the shallow layer subcutaneous tissue in a non-invasion mode, liquid medicine absorption of human skin is promoted, no damage is caused to the human body, the injection amount of the liquid medicine and the injection treatment area can be controlled, and the better treatment effect is achieved.