A structured testing method (200, 300, 388) and device (18) for diagnosis or treatment support of a chronic disease patient (12) are disclosed. The device (18) implements a medical usage and/or question based structured collection process (70) that provides at least one or more parameters (220, 222, 224, 226, 228, 230, 232, 237, 238, 240), said parameters (220, 222, 224, 226, 228, 230, 232, 237, 238, 240) define at least one entry criterion (226), event schedule (222), at least A compliance criterion (224) and at least one exit criterion (228). Entry criteria (226) establish conditions that need to be met before obtaining biomarker data (256) from patient (12). Each event (237) in the event schedule (222) may include a delivery time (238), instructions (230) for carrying out the event (237), a request for information from the patient (12) (240), an At least one or more of a request (240) for an action and a request (240) for collection of at least one type of biomarker data (256) from the patient (12). Adherence criteria (224) are used to qualitatively assess whether events (237) delivered against event schedules (222) provide acceptable data (256, 170, 145) to address medical usage and/or issues, and exit criteria (228 ) establishes the conditions that need to be met before the structured collection process (70) exits.