The invention relates to a method for removing moisture from chloroethylene or gas mixture with chloroethylene. The method comprises the following steps: sending moisture-contained chloroethylene or gas mixture with chloroethylene from the entrance end into a dryer which is at least filled with macropore silica gel and 5A molecular sieve desiccant; performing adsorption drying under the gauge pressure of 0.30-0.70MPa; obtaining dry chloroethylene or gas mixture product with chloroethylene from the exit end of the dryer, at least heating desiccant in the dryer for desorption and cooling the desiccant to regenerate the desiccant, and performing the next adsorption drying operation repeatedly, wherein the average pore diameter of the silica-gel desiccant is 8.0-10.0nm, the specific surface area is 300-400m<2>/g, the pore volume is 0.8-1.0ml/g and the heat regeneration temperature of the desiccant is 70-150 DEG C. The total moisture content of the gas product dried by the method of the invention is up to (10-100)*10<-6>; and compared with the common drying methods and technologies such as solid caustic soda method, before and subsequent gravity dewatering method and coalescer dewatering and drying method, the method has the advantages of high dewatering accuracy, low operating cost, high recovery rate, more environmental friend and the like.