The invention belongs to the field of computer vision, and discloses a three-dimensional model deformation algorithm based on quasi-conformal mapping. The method comprises the following steps of firstly, parameterizing a three-dimensional model to a two-dimensional plane disc by utilizing the quasi-conformal mapping, secondly, adopting a quasi-common iterative algorithm to calculate the mapping between the two planes, and obtaining a deformed two-dimensional model, and finally, restoring the deformed two-dimensional model into a three-dimensional model meeting constraint conditions as much aspossible by adopting a 2D-to-3D model restoration algorithm. According to the present invention, the problems that an existing model is low in utilization rate, the number of control points needing tobe operated by a deformation algorithm is large, the model processing effect on skeletons is poor, the differential coordinate deformation technology is sensitive to rotation, and the direct deformation on a three-dimensional model is difficult, are solved. Compared with a traditional mapping method, the method is simple, and keeps more local details of the source mode. The method is suitable forthe three-dimensional model deformation based on a single image, and is suitable for the deformation of a model with any boundary. The method can be applied to the fields of animation, cosmetic surgery, medicine, geometric modeling and the like.