Carrier aggregation (CA) may cause interference between operation on two or more carriers within a user equipment (UE). This interference can degrade signal quality on one or more of the carriers involved in the carrier aggregation, which may be referred to as "desensing" one or more carriers. One or more isolating buffers may be coupled at a down-conversion mixer at a point where the down-conversion mixer receives a signal from a transmission line for isolating the transmission line from other transmission lines. The isolating buffer may reduce the effect of interference between multiple transmission lines carrying different carriers during carrier aggregation (CA) operation. The isolating buffers may be used in an RF transceiver supporting both 5G sub-7 GHz and 5G mmWave wireless networks and carrier aggregation across sub-7 GHz and mmWave bands.