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4 results about "Optical mapping" patented technology

Optical mapping is a technique for constructing ordered, genome-wide, high-resolution restriction maps from single, stained molecules of DNA, called "optical maps". By mapping the location of restriction enzyme sites along the unknown DNA of an organism, the spectrum of resulting DNA fragments collectively serves as a unique "fingerprint" or "barcode" for that sequence. Originally developed by Dr. David C. Schwartz and his lab at NYU in the 1990s this method has since been integral to the assembly process of many large-scale sequencing projects for both microbial and eukaryotic genomes. Later technologies use DNA melting, DNA competitive binding or enzymatic labelling in order to create the optical mappings.

Space intelligent non-planar reflection generation method based on surface normal guidance

The invention provides a space intelligent non-planar reflection generation method based on surface normal guidance. Extracting multi-layer visual representation from an original RGB image containing a non-planar reflection medium scene, and identifying a non-planar reflection area by combining brightness distribution of the original RGB image and a spatial symmetry relation; analyzing non-linear deformation features of textures in the non-planar reflection area, and predicting pixel-level three-dimensional surface normal vectors and confidence distribution in combination with multi-layer visual representation to construct a surface normal graph; determining a line-of-sight vector based on a camera imaging model, and executing geometrical optical mapping operation on the line-of-sight vector, the surface normal graph and the confidence distribution to construct a reflection offset field; extracting an intermediate semantic feature representation corresponding to the non-planar reflection region, and generating a pre-distortion reflection feature representation according to the reflection offset field and the intermediate semantic feature representation; and injecting the pre-distortion reflection feature representation, the multi-layer visual representation and the initial reflection area mask into a generative model for image reconstruction, and generating a non-planar reflection image.
Owner:BEIJING FEIDU TECH CO LTD

Photon temperature measurement method and system based on single microcavity double optical comb reading

PendingCN122505425AOptical mappingRadio frequency signal
This invention provides a photonic temperature measurement method and system based on single-microcavity dual-optical-comb readout, relating to the field of photonic sensing technology. The method includes: acquiring a dual-path soliton optical comb propagating in reverse within a single microcavity; inputting the combined beam of the dual-path soliton optical comb into a temperature sensing unit to acquire radio frequency (RF) signal data and corresponding standard temperature data of the temperature sensing unit at different temperatures; determining the center wavelength data of the resonant mode of the temperature sensing unit based on the RF signal data; linearly fitting the average value of the standard temperature data and the center wavelength data of the resonant mode to obtain the thermo-optical mapping relationship of the temperature sensing unit; the thermo-optical mapping relationship is used to measure the temperature of the object under test via optical signals. The photonic temperature measurement method and system based on single-microcavity dual-optical-comb readout provided by this invention establishes a stable quantitative mapping relationship between optical signal wavelength and temperature, achieving both a wide measurement range and high measurement speed in scenarios with rapid temperature changes.
Owner:NATIONAL INSTITUTE OF METROLOGY CHINA

Artificial intelligence trained with optical mapping to improve detection of cardiac arrhythmia sources

ActiveUS12676235B2Optical mappingCardiac arrhythmia
Disclosed are various embodiments of methods, components and systems configured to determine a location of a source of cardiac arrhythmia in a patient's heart. In some embodiments, to determine a source location, electrogram signals are acquired from a region of the patients' heart using a first set of electrodes; and then a pre-trained artificial intelligence (AI) model is applied to predict the location of the cardiac arrhythmia source by using the signals. Importantly, pre-training of the AI model comprises acquiring electrogram signals from explanted human hearts, the signals are generated by a second set of electrodes assembled into an electrode array that covers at least a part of the explanted human heart, and acquiring co-registered functional and / or structural imaging data in the part of the explanted human heart covered with the electrode array, wherein the functional and / or structural imaging data provide location of at least one source of cardiac arrhythmia.
Owner:AVTONOMNAYA NEKOMMERCHESKAYA OBRAZOVATELNAYA ORGANIZATSIYA VYSSHEGO OBRAZOVANIYA SKOLKOVSKIJ INST NAUKI I TEKHNOLOGIJ +1

Electro-optical mapping system and method for electronic intelligent model

The invention provides an electronic intelligent model-oriented electro-optical mapping system and method, and the system comprises a semantic feature extraction module which is used for carrying out the semantic feature coding of an input image, text or multi-modal data, and outputting a semantic feature representation representing the calculation capability of an electronic intelligent model; the optical parameter generation module is used for generating optical calculation parameters for driving the optical calculation module according to the semantic feature representation under the condition of introducing a physical constraint condition of the target optical calculation module; and the optical calculation module is used for executing optical calculation based on the optical calculation parameters so as to reproduce the corresponding calculation capability of the electronic intelligent model in a function or calculation behavior level and realize mapping of the electronic intelligent model to the optical calculation system. According to the application, the efficient mapping and reliable deployment of the electronic intelligent model to the optical computing system can be realized without directly mapping the complete digital weight of the electronic model.
Owner:SHANGHAI JIAOTONG UNIV