The invention discloses a semiconductor structure, a forming method and a mask, and the method comprises the steps: providing a substrate, wherein the substrate comprises a first device region, a pseudo device region, a second device region and a third device region which are sequentially arranged along a first row, and a third device region, a second device region, a pseudo device region and a first device region which are sequentially arranged along a second row. The first device region, the pseudo device region, the second device region and the third device region in the first row are in central symmetry with the first device region, the pseudo device region, the second device region and the third device region in the second row respectively According to the embodiment of the invention, a first shielding layer exposes the first device region and the pseudo device region, and the exposed area of the first shielding layer is large, so that the process window of the first shielding layer is large, the process difficulty of forming the first shielding layer is reduced, and the overlay precision of the first shielding layer is improved.