106results about How to "Easily determine" patented technology

Use of lipid conjugates in the treatment of disease

The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels. The surprisingly manifold pharmacological properties of the PL-conjugates allow for the invention, disclosed herein, of novel methods for the treatment of a diverse range of disease states, including obstructive respiratory disease, including asthma; colitis and Crohn's disease; central nervous system insult, including blood brain barrier compromise, ischemic stroke, and multiple sclerosis; contact dermatitis; psoriasis; cardiovascular disease, including ischemic conditions and prophylaxis for invasive vascular procedures; cellular proliferative disorders, including anti-tumor vasculogenesis, invasiveness, and metastases; anti-oxidant therapy; hemolytic syndromes; sepsis; acute respiratory distress syndrome; tissue transplant rejection syndromes; autoimmune disease; viral infection; and hypersensitivity conjunctivitis. The therapeutic methods of the invention include administration of phosphatidylethanolamine bound to carboxymethylcellulose, heparin, hyaluronic acid, polyethylene glycol, and hemaccel. Disclosed herein are also new compounds comprised of phospholipid moieties bound to low molecular weight monomers and dimers, including mono- and disaccharides, carboxylated disaccharides, mono- and dicarboxylic acids, salicylates, bile acids, and fatty acids.

Three-dimensional image display apparatus and method

A three-dimensional image display apparatus is provided that can integrate and visualize 3D measurement data obtained from a stereo image with an image of a measuring object to which stereoscopic texture is applied. The apparatus includes: an orientation section 24 for finding relationship as to corresponding points in a stereo image of a measuring object 1 based on the position and the tilt at which the stereo image was photographed; a three-dimensional coordinate data section 31 for obtaining three-dimensional coordinate data on the corresponding points of the measuring object 1 based on the relationship as to the corresponding points found by the orientation section 24; a model forming section 32 for forming a model of the measuring object 1 based on the three-dimensional coordinate data on the corresponding points; an image correlating section 34 for correlating the stereo image of the measuring object stored in the stereo image data storage section 12 and the model formed by the model forming section 32, using the relationship as to the corresponding points found by the orientation section 24; and a model display section 35 for displaying an image of the measuring object 1 to which stereoscopic texture is applied, using the stereo image correlated with the model by the image correlating section 34.

Knowledge-forming apparatus and parameter-retrieving method as well as program product

A device that is capable of easily determining discrimination knowledge suitable for recognizing a normal/abnormal state of an object to be inspected in an inspecting and diagnosing apparatus is provided with: a parameter-retrieving unit that retrieves various parameter sets used for calculating feature amounts, a feature-amount operation unit that calculates a plurality of feature amounts based upon the respective parameter sets that have been retrieved by the retrieving unit in association with learning data that includes given normal data and abnormal data, a primary evaluation unit that outputs the effectiveness of each of the parameter sets as evaluated values based upon the results of the operation of the feature amounts calculated by the feature-amount operation unit, an optimal solution candidate output unit that, based upon the results of the primary evaluation found by the primary evaluation unit, outputs the results of a plurality of parameter sets having a high primary evaluated value as a plurality of optimal solution candidates, a discrimination knowledge forming unit that forms a plurality of discrimination knowledge based upon the optimal solution candidates output from the optimal solution candidate output unit, a secondary evaluation unit that evaluates on each of the discrimination knowledge that have been formed in the discrimination knowledge forming unit and an optimal solution output unit that, based upon the results of the secondary evaluation, outputs the discrimination knowledge having a high evaluated value as an optimal solution.
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