The invention discloses a manufacturing method of a CuNi90/10 alloy socket welding flange. The manufacturing method comprises the following steps that S1, die manufacturing is conducted, specifically,an outer die and a punch are manufactured according to the boundary dimension of the CuNi90/10 alloy socket welding flange; S2, heating and blank making are conducted, specifically, a CuNi90/10 alloyingot is heated to a forging temperature, the temperature is kept for a certain period of time according to the diameter of the ingot, and the ingot is forged on a forging hammer into a blank capableof being put into the outer die; S4, die preheating is conducted, specifically, the die manufactured in the step S1 is preheated in a heating furnace, and the blank manufactured in the step S2 is putinto the outer die for die pressing until a die cavity is filled with CuNi90/10 alloy; S5, punching is conducted, specifically, blind hole punching and through hole punching are sequentially conducted on the die-pressed CuNi90/10 alloy through the punch; and S6, cooling is conducted, specifically, after die forging, the CuNi90/10 alloy material is withdrawn from the die cavity, cooling treatmentis conducted on the CuNi90/10 alloy material, and then the CuNi90/10 alloy socket welding flange is obtained through turning. The manufacturing method is reasonable and effective, and has the advantages of raw material saving, small cutting amount, low production cost, high performance of manufactured products and the like.